Franziska Heydenreich, Sudarshan Rajagopal, Graham Ladds, Cesare Orlandi and Michel Bouvier. Additionally, if you participated in our Symposia in 2023, please take a moment to fill out this survey GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd GPCRs Summit in Boston on March 5-7, 2024. April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 -

Sudha K Shenoy et al. Franziska Heydenreich, Sudarshan Rajagopal, Graham Ladds, and Michel Bouvier. Additionally, if you participated in our Symposia in 2023, please take a moment to fill out this survey GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd GPCRs Summit in Boston on March 5-7, 2024.

Franziska Heydenreich, Sudarshan Rajagopal, Graham Ladds, and Michel Bouvier We will also have a poster Take 2 minutes to fill out this survey and let us know what you liked, what you didn’t, and what we can We’ll send your contributor articles to our community, keep you updated with GPCR papers, receive support GPCR Partnered Events 3rd GPCRs - Targeted Drug Discovery Summit  Join us at the 3rd GPCRs Targeted Drug Discovery Summit in Boston on March 5-7, 2024.

GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit  We're partnering again with the 3rd GPCRs - Targeted Drug Discovery Summit in Boston on March 5-7, 2024. GPCR at the Endocrine Metabolic GPCRs Summit on April 22-23, 2024, in Birmingham, UK. Dr. Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting NEW March 13 - 15 | 9th German Pharm-Tox Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 -

GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Exciting news! We're partnering again with the 3rd GPCRs - Targeted Drug Discovery Summit in Boston on March 5-7, 2024 Places to Work Certification in 2023 Orion Biotechnology will be presenting at the OBIO 2024 Investment Summit Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit May 16 -

February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

tetraspanins: A universal system for numbering residues and a proposal for naming structural motifs and subfamilies analysis of chemosensory-related gene families in gastropods Unraveling the G protein-coupled receptor superfamily February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

has increasingly focused on cancer, where tumors hijack the chemokine system to provide growth and survival Different reviews have extensively described the success and failure in drug discovery on chemokine receptors Japan and by the FDA for the treatment of mycosis fungoides or Sézary syndrome in adults which are subtypes Subsequent reports characterizing small molecule agonists for CXCR3 further substantiated the notion (Mack et al. 1998), CCR3 is partially restored to the cell surface and partially targeted to lysosomes

We appreciate your continued support and readership. February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

mansoni A Novel Flp Reporter Mouse Shows That TRPA1 Expression Is Largely Limited to Sensory Neuron Subsets February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Conference April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry April 4 - 7, 2024 | American Physiology Summit Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

Discover our comprehensive coverage of GPCRs, We welcome GPCR paper suggestions! Submit your publications to Hello@DrGPCR.com for consideration. This week's highlight: Dr. Subscribe for this month's video featuring Dr. Alix Rouault. Be sure to look at the Classified GPCR News from November 27th to December 3rd, 2023. GPCR Activation and Signaling DANGER Signals Activate G -Protein Receptor Kinases Suppressing Neutrophil

We welcome GPCR paper suggestions! Submit your publications to Hello@DrGPCR.com for consideration. Tobias Langenhan for his papers to highlight suggestions GAIN Domain Unfolding in Adhesion GPCRs Molecular Subscribe now! Don't miss the upcoming episodes of Dr.GPCR Podcast featuring Dr. and Assay Services $3bn sales potential for drug Sosei Heptares wants back from GSK Novartis drops subpoena Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

those who joined any of our symposium sessions, we kindly request a moment of your time to fill out our survey parathyroid hormone (PTH) type 1 receptor biology β-arrestin1 is an E3 ubiquitin ligase adaptor for substrate salt challenge in the Dahl SS rat GPCRs in Neuroscience Neurokinin-2 receptor negatively modulates substance April 1 - 4, 2024 | 19th Annual Drug Discovery Chemistry NEW April 4 - 7, 2024 | American Physiology Summit Meeting April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

You can find more details about the speakers on the Live Talks page, and make sure to mark your calendar Kathleen Caron, as our video guest, subscribe now! GPCR Activation and Signaling Neuronal survival factor TAFA2 suppresses apoptosis through binding to International Conference and Exhibition NEW March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Meeting NEW April 22 - 23, 2024 | Endocrine Metabolic GPCRs May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

β-strand folding of phosphorylation clusters guides GPCR binding to arrestin Dietary dibutyryl cAMP supplementation transcription factor 21 GPCRs in Neuroscience Pregabalin inhibits purinergic P2Y2 receptor and TRPV4 to suppress Heptares Will Receive US$3.75 Million Payment in Multi-Target Partnership Sosei Heptares Announces Submission Amgen noncommittal on oral obesity med until phase 1 data arrive Form and Function - Consequences of subcellular Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

If you're attending the GPCR Retreat, be sure to swing by our booth and snap a photo at our banner! Get the inside scoop by subscribing to our monthly Dr. Signaling The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

the intracellular allosteric site GPCRs represent one of the largest and most vital families of cell surface While this has the potential to enhance GPCR subtype-selectivity, it also presents a significant challenge target selectivity, which can arise from greater sequence variation in allosteric sites among receptor subtypes when compared to the conserved orthosteric region, or from selective cooperativity with a particular subtype This is particularly important when dealing with receptor subtypes that exhibit significant similarity

Sakmar and his team used 'bioluminescence resonance energy transfer to measure cell-surface expression Submit your logo design by Nov 1st on the Logo Contest page. Subscribe to Dr. GPCR Newsletter for more insights! for novel drug discovery Application of bioluminescence resonance energy transfer to quantitate cell-surface Data for AI-designed LSD1 and MALT1 Inhibitors at ESMO 2023 Restoring the function of a human cell surface

Submit a logo design by Nov 1st on the Logo Contest page. No registration is needed to submit your logo design. Subscribe to Dr. activates two G protein-coupled receptors with differential second messengers for diuresis in Drosophila suzukii Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi3 Celebrating Lefkowitz’s 50 Years at Duke Novo Nordisk stops Ozempic kidney trial after early signs of success

Submit a logo design by Nov 1st on the Logo Contest page. No registration is needed to submit your logo design. Subscribe now to Dr. G-protein-coupled receptor Target for Therapeutic Development DKK 25 million to development of databases supporting medical research ‘Define your own success’: Duke leaders talk success, failure at symposium honoring Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

You can submit your logo design by November 1st, and registration is unnecessary to participate. Also, If you attended any of the talks, we'd truly value your feedback through our survey. Subscribe now to gain access to exclusive insights from Dr. GPCR Newsletter! GPCR Activation and Signaling The non-nutritive sweetener sucralose increases β-arrestin signaling at Research Polyphosphate uses mTOR, pyrophosphate, and Rho GTPase components to potentiate bacterial survival

For attendees, kindly spare a moment to complete our survey. If you're already registered, kindly use the provided form to submit your poster abstracts. Abstract submissions close on October 2nd. Submit your logo design by November 1st. You don't need to be registered to participate. Access exclusive insights by subscribing to the Dr. GPCR Newsletter!

conformational selection: Nanobodies have a unique shape that allows them to bind to cavities or clefts on the surfaces Nbs can stabilize specific conformations of proteins, including unstable structural intermediates and substates This Nbs binds to the extracellular surface of the Rhodopsin receptor and stabilizes the photo-activated S., Schnapp, A., Konetzki, I., Sunahara, R. K., Gellman, S. H., Pautsch, A., Steyaert, J., Weis, W.

If you have registered, please submit poster abstracts through this form and the short talk selections Abstract submissions close on October 2nd. Subscribe to the Dr. S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning Prediction of survival Gating Conference April 5 - 10, 2024 | AACR Annual Meeting May 13 - 17, 2024 | 20th Annual PEGS Boston Summit Conference and Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Research Technician II - Surgery

GPCR, was featured as Superluminal Medicines Launches to Drug Protein Conformations in a Flash. Christopher Langmead and colleagues' work on the 5-HT2C receptor as a therapeutic target for substance Submit poster abstracts here; short talks will be selected from Abstracts. Abstract submissions close on October 2, and final registration ends on September 21. Subscribe to the Dr. GPCR Newsletter for more insights!

You can submit your poster abstracts using this form and short talks will be selected from abstracts. Please remember that the early-bird registration deadline ends tomorrow, the abstract submissions deadline Subscribe to Dr. GPCR Newsletter to gain access to further insights! Bacillus thuringiensis Cry4B toxin involves Na+/K+ ATPase GPCR Promiscuity Reshapes Islet Physiology TGR5 supresses Morgan Stanley 21st Annual Global Healthcare Conference CEO Raymond Stevens to Speak at STAT Future Summit

Sudarshan Rajagopal and their lab team study on 'Location bias: A "Hidden Variable" in GPCR pharmacology Submit poster abstracts via this form; short talks will be selected. Early-bird registration deadline is September 8, abstract submissions close on October 2, and final registration Subscribe to Dr. GPCR Newsletter to receive more insights! Conference NEW April 5 - 10, 2024 | AACR Annual Meeting NEW May 13 - 17, 2024 | 20th Annual PEGS Boston Summit

Abstract submission for oral presentations closes at 11:30 pm EST today! Abstract submission for poster presentations closes at 11:30 pm EST on August 30, 2023. Submit poster abstracts using this form; short talks will be selected from submissions. Early-bird registration and abstract submissions close on September 8, and final registration ends on