Stay tuned for our next symposium on GPCRs as Therapeutics Targets on October 11th, 2024. phospho-drug-associated pruritus in a humanized mouse model GPCRs in Cardiology, Endocrinology, and Taste The Genetic Pathophysiology and Clinical Management of the TADopathy, X-Linked Acrogigantism Thrombosis regulation of the glucagon receptor family Technologies for the discovery of G protein-coupled receptor-targeting inflammation, resolution and beyond Exploring GPCR signaling pathway networks as cancer therapeutic targets

The ONE-GO biosensors, designed in a single vector, incorporate a G protein tagged with a YFP acceptor and a G protein detector tagged with an Nluc donor.

Please complete this form to take advantage of this opportunity on a first-come, first-served basis. macrocyclic peptide modulators of the cannabinoid 2 receptor GPCRs in Cardiology, Endocrinology, and Taste

Please complete this form to take advantage of this opportunity on a first-come, first-served basis. Oncology and Immunology Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target

biochemical, cell based, and radioligand binding assays to enable SAR, MOA, lead optimization, and new target

Virtual Screening of a Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target Please complete this form to take advantage of this opportunity. If you've participated in our symposiums, please take a few minutes to complete this survey. GPCRs in Cardiology, Endocrinology, and Taste Orphan GPCR GPRC5C Facilitates Angiotensin II-Induced Smooth Muscle Contraction GPCRs in Neuroscience Evolutionary origins of bitter taste receptors in jawed

research sparked a new era of a comprehensive understanding of GPCR biology, the development of GPCR-targeted drugs, and the exploration of GPCRs as key regulators of physiological processes and therapeutic targets The completion of the Human Genome Project revealed that GPCR genes in the human genome range from approximately approaches, such as structural bioinformatics analysis, have facilitated drug discovery and design targeting bioinformatics, and clinical research has opened new avenues for exploring GPCR biology, developing targeted

Please complete this form to take advantage of this opportunity. If you've participated in our symposiums, please take a few minutes to complete this survey. protein-coupled receptors using a multi-graph convolutional network GPCRs in Cardiology, Endocrinology, and Taste

University courses in the next 12 months -  Only applicable to individual registrations This course will take Take advantage of the early bird registration until April 18th, 2024, to save 25%! Please complete this form to take advantage of this opportunity. If you want to showcase your research, you can submit a poster presentation to our community, take advantage

GPCRs are present in a range of conformations, and the binding of a ligand, as well as interactions with GPCR targeting drugs: orthosteric vs allosteric sites Most of the drugs targeting GPCRs bind to the orthosteric Those include the risk of unintended off-target effects, limited selectivity due to closely related receptor binding sites, the inability to target large and diffuse binding sites activated by peptides or proteins Moreover, they have the potential to enhance target selectivity, which can arise from greater sequence

If you want to showcase your research, you can submit a poster presentation to our community, take advantage autophagy in health and disease GPCR Binders, Drugs, and more Elucidation of active components and target the treatment of prostatitis and benign prostatic hyperplasia GPCRs in Cardiology, Endocrinology, and Taste

If you participated in our symposiums, please take a moment to complete this survey. Insights from Gαi3 research GPCRs in Cardiology, Endocrinology, and Taste The Prostaglandin E2 EP3 Receptor

Industry News Boehringer Ingelheim and Sosei Heptares join forces to develop first-in-class treatments targeting

If you attended our 2023 Symposia, please take a moment to complete this survey. Dr. protein-coupled receptor regulates ischaemia-reperfusion injury GPCRs in Cardiology, Endocrinology, and Taste after myocardial infarction through β1 adrenergic receptor GPCRs in Neuroscience Discovery of potential TAAR1 agonist targeting neurological and psychiatric disorders: An in silico approach Opioid modulation of discovery in endocrinology and metabolism Reviews, GPCRs, and more Butyrate as a promising therapeutic target

If you attended our 2023 Symposia, please take a moment to complete this survey. Dr. GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit. Join Dr. Visualized by Branched In Situ Hybridization Chain Reaction Orphan GPR52 as an emerging neurotherapeutic target

Additionally, if you participated in our Symposia in 2023, please take a moment to fill out this survey GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd small-molecule agonist for the atypical chemokine receptor ACKR3 GPCRs in Cardiology, Endocrinology, and Taste in GPCR Pharmacology: Unraveling the Secrets of Cellular Communication Bowes Biomedical Investigator Takes

Additionally, if you participated in our Symposia in 2023, please take a moment to fill out this survey GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd modulation and G-protein selectivity of the Ca2+-sensing receptor GPCRs in Cardiology, Endocrinology, and Taste

Additionally, if you participated in our Symposia in 2023, please take a moment to fill out this survey GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Join us at the 3rd ghrelin receptor agonist capromorelin in veterinary medicine GPCRs in Cardiology, Endocrinology, and Taste membrane Industry News Launch of GIO Therapeutics, founded by Cumulus Oncology, to develop therapeutics targeting

Take 2 minutes to fill out this survey and let us know what you liked, what you didn’t, and what we can GPCR Partnered Events 3rd GPCRs - Targeted Drug Discovery Summit  Join us at the 3rd GPCRs Targeted Drug Decrypting orphan GPCR drug discovery via multitask learning GPCRs in Cardiology, Endocrinology, and Taste

GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit  We're partnering again with the 3rd GPCRs - Targeted Drug Discovery Summit in Boston on March 5-7, 2024. Study for the Unresolved Inactive Human Adenosine A3 Receptor GPCRs in Cardiology, Endocrinology, and Taste Hepatic Regulator of G protein Signaling 14 Ameliorates NAFLD through Activating cAMP-AMPK Signaling by Targeting rescue option for asthma GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

GPCR Partnered Events March 5 - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit Exciting news! We're partnering again with the 3rd GPCRs - Targeted Drug Discovery Summit in Boston on March 5-7, 2024 Adrenergic Receptor: Insights from Molecular Dynamics Simulations GPCRs in Cardiology, Endocrinology, and Taste ) Ketone bodies as chemical signals for the immune system AI-driven GPCR analysis, engineering, and targeting Addiction Treatment AEF0117 GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

extracellular loops on a soluble scaffold enabled the discovery of antibodies, which recognized native receptor Targeting Morgan Healthcare Conference Isomorphic Labs Announces Strategic Multi-Target Research Collaboration With Novartis Salipro Biotech announces multi-target research collaboration with an additional Top5 crop protection company GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk Conference and Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted

mediated by human neutrophil expressed formyl peptide receptors GPCRs in Cardiology, Endocrinology, and Taste Optimized design and in vivo application of optogenetically functionalized Drosophila dopamine receptors Targeting Advance Novel Gene Therapies GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk Conference and Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted

The GPCR Weekly News will take a holiday break. and enhanced transcriptional outputs at neurokinin receptor-1 GPCRs in Cardiology, Endocrinology, and Taste Trapped-Ion-Mobility Spectrometry Coupled to Time-of-Flight Mass Spectrometry (TIMS-TOF MS) A rapid, tag-free way to purify functional GPCRs tANCHOR fast and cost-effective cell-based immunization approach with Strengthen Neuroscience Pipeline GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

Nouvelle-Aquitaine Region Governor GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk Conference and Exhibition February 11 - 14, 2024 | 2024 BPS Annual Meeting March 5 - 7, 2024 | 3rd GPCRs - Targeted

disease therapy Rational design of highly stabilized and selective adrenomedullin analogs Novel multi-target Receptors Ligands: New Potential Therapeutic Natural Drugs GPCRs in Cardiology, Endocrinology, and Taste complex Deep Learning Dynamic Allostery of G-Protein-Coupled Receptors Industry News Sosei Heptares to take Carmot Therapeutics Enters into Definitive Merger Agreement with Roche New Clinical Trial Explores Novel Target In Parkinson’s Treatment GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

Take a few minutes, and dive into our GPCR coverage! We welcome GPCR paper suggestions! of PLCβ3-catalyzed PIP2 hydrolysis GPCR Binders, Drugs, and more Discovery of Guanfacine as a Novel TAAR1 Pakistan Structural and Molecular Insights into GPCR Function Structural and signaling mechanisms of TAAR1 for drug Sosei Heptares wants back from GSK Novartis drops subpoena request in trade-secret spat with Takeda Discovery and Development GPCR Events, Meetings, and Webinars January 16 - 19, 2024 | 23rd Annual PEP Talk

cannabidiol-dimethylheptyl, but not cannabidiol, on the cannabinoid CB2 receptor GPCRs in Cardiology, Endocrinology, and Taste Engineering Platform for Genetically Encoded Fluorescent Indicators Design of an effective small expression tag Completes Recruitment of Patients Sanyou Bio's Evolution of Bioprocess Enhancement for CHO Cell Lines: A Talk Conference November 20 - 23, 2023 | ASCEPT Annual Scientific Meeting January 16 - 19, 2024 | 23rd Annual PEP Talk February 3 - 7, 2024 | SLAS2024 International Conference and Exhibition March 5 - 7, 2024 | 3rd GPCRs - Targeted