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115 items found for "InterAx Biotech"
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
In this study, we elucidate the tripartite interaction between LPA-signaling, UCA1, and let-7 miRNAs
- RNAi library screening reveals Gβ1, Casein Kinase 2 and ICAP-1 as novel regulators of LFA-1-mediated T cell polarity and migration
endothelial vasculature and migration into both secondary lymphoid organs and peripheral tissues via interactions
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
Docking results revealed that the GPR35-targeting compounds interacted at the key residues for the agonist-initiated
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
differentiation, negative regulation of T cell receptor signaling pathway, neuroactive ligand receptor interaction
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
Furthermore, interacting partners were found via correlation and enriched to explain their antagonistic
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
The fall colors of the leaves are spectacular, and the weekend of science is an intense and interactive
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
These domains form a compact module mediated by robust and evolutionarily conserved interdomain interactions Mutational experiments on residues of interest showed that restoring the Phe-His interaction in the uncleaving
- Ep 50 with Dr. Thomas P. Sakmar
discover a “counterion switch” in visual pigments and to develop strategies to assay receptor-G-protein interactions
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
Differential expression and functional enrichment analyses were performed; protein-protein interaction
- Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity
dual-function CXC chemokine that coordinates chemotaxis of activated T cells and natural killer (NK) cells via interaction
- Ep 107 with Dr. Roger Sunahara
Sunahara lab utilizes biochemical, biophysical and pharmacological methodologies to study GPCR-G protein interactions
- Ep 146 with Dr Michael Feigin
The team found that these drugs could interact with GPR68, which is highly expressed in cancer-associated in mammary epithelial cells, the effect of alprazolam on tumors, and the potential dangers of drug interactions
- Content Guidelines | Dr. GPCR Ecosystem
Review updates: Review updates should reflect a new experience or interaction with the business.
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
GFs were isolated with enzymic digestion and transfected with 30, 50 and 80 μmol/L small interfering RNA-GPRC5A (siGPRC5A) or small interfering RNA-negative control (siNC), regarded as the experimental Moreover, GPRC5A played a role in inflammation regulation by interacting with NF-κB signaling pathway
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
We describe the neuroimmune interactions that underlie the various sensory and autonomic pathologies
- Ep 80 with Dr. Andrew Tobin
Andrew is translating fundamental findings to commercial products is Keltic Pharma Therapeutics Ltd , a biotechnology
- Ep 60 with Dr. Josephine (Pina) Cardarelli
based in South Korea, has recently been named President of GPCR Therapeutics, USA, a newly incorporated Biotechnology
- Ep 73 with Dr. Aylin Hanyaloglu
Her work is currently funded by Biotechnology and Biological Sciences Research Council (BBSRC), Diabetes
- GPCR Retreat 2023 - Part I
oncology research led me to pursue a BSc in Biology & Economics from Carleton University, and an MSc in Biotechnology In my role at Orion Biotechnology, I work at the intersection of science and business, which includes An advocate for trainees at all levels, she served as Service Chairperson and Interim President of the
- Ep 91 with Dr. Oliver Hartley
Oliver Hartley Oliver Hartley is VP for Drug Discovery at Orion Biotechnology . Oliver Hartley on the web LinkedIn Orion Biotechnology Dr.
- Ep 135 with Dr. Katarzyna Marcinkiewicz
following three years on the editorial teams of Nature Structural and Molecular Biology and Nature Biotechnology
- Ep 116 with Dr. Shivani Sachdev
She received her undergraduate degree in Biotechnology from KIIT University in India.
- Ep 15 with Dr. Arun Shukla
He earned his master's degree in biotechnology from Jawaharlal Nehru University in India and it was during
- Ep 112 with Julia Gardner
Last summer, Julia worked at as the first-ever summer intern at Septerna, the GPCR-based biotechnology
- Ep 19 with Dr. Fiona Marshall
of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery and development biotechnology
- Ep 45 with Dr Ralf Jockers
Ralf Jockers Ralf Jockers studied in Cologne and received a Ph.D. in biotechnology and biochemistry from He was the director of the French network of GPCRs (GDR-3545), currently directs the International Research
- Ep 53 with Dr. Timo De Groof
Timo De Groof studied Biochemistry and Biotechnology at the University of Ghent where he graduated in During his master's studies, he specialized in Biomedical Biotechnology and Structural Biology/Biochemistry
- Flash News / DrGPCR
News—your go-to spot for the latest, real-time updates in the world of GPCR research, pharmacology, and biotechnology high-affinity-elr%2B-chemokine-ligands-show-g-protein-bias-over-%CE%B2-arrestin-recruitment-and-receptor-internalization-in-cxcr1