At Harvard, I worked in the labs of Drs. Brian Kobilka at Stanford University at the end of 2017 for postdoctoral work. John Janetzko on the web Stanford University Stanford Medicine Google Scholar Personal Website ResearchGate He then moved to Dan's lab where he met Suzanne and her project. John also discussed the potential complications that arose when his then-girlfriend, now wife, was applying

During his doctoral work in the lab of Prof. Lefkowitz , where his research focused on biased agonism, with the development of approaches to quantify Sudarshan Rajagopal on the web LinkedIn Website Google Scholar LinkedIn Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

Steve’s work is focused on emerging technologies applied to Science, Technology, Engineering, and Mathematics During his time at UC San Diego Steve worked directly with the founding Chair of the Nanoengineering graduating from UCSD he founded Nanome Inc to build Virtual Reality solutions for Scientists and Engineers working Steve McCloskey on the web Website LinkedIn Twitter ResearchGate Medium Orchid Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

dogma is that chemoattractants G protein-coupled receptors (GPCRs) activate β phospholipase C (PLCβ) while Here, we show that chemoattractant/GPCR-mediated membrane recruitment of PLCγ2 constitutes GPCR-mediated The study reveals a molecular mechanism of membrane targeting of PLCγ2 and the signaling pathways by which PLCγ2 plays an essential role in neutrophil chemotaxis. " Authors Xuehua Xu , Xi Wen , Smit Bhimani GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

) exhibits unknown functions in tumors, particularly in non-small-cell lung cancer (NSCLC) METHODS: We We detected the expression of GPR37 in NSCLC tissues and cell lines. Furthermore, we examined the effects of GPR37 on tumor cell apoptosis and invasion. Most importantly, we investigated whether GPR37 affects cisplatin-induced drug resistance in NSCLC. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Abstract " The CC chemokine receptor 6 (CCR6) is a G protein-coupled receptor (GPCR) involved in a wide When CCR6 binds to its sole ligand CCL20, a signaling network is produced. Th17 cells express the CCR6 receptor and inflammatory cytokines, including IL-17, IL-21 and IL-22, which Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

finding that statins inhibit membrane association of G protein γ (Gγ) in a subtype-dependent manner, we We examined the prenylation of carboxy-terminus (Ct) mutated Gγ in cells exposed to Fluvastatin and prenyl Authors Mithila Tennakoon , Waruna Thotamune , John L Payton , Ajith Karunarathne Tags HMG-CoA reductase Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

In this article, we review ITA metabolism and its regulation, discuss its target proteins and mechanisms Authors Dan Ye , Pu Wang , Lei-Lei Chen , Kun-Liang Guan , Yue Xiong Tags IRG1/ACOD1 , cancer , inflammatory Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Abstract "Efficient induction of humoral immune responses depends on orchestrated migration of B cells within lymphoid organs, which is governed by G protein-coupled receptors (GPCRs) responding to chemoattractants GPCRs are phosphorylated by different GPCR kinases (GRKs) at distinct sites on the receptor C termini, which However, the molecular mechanisms by which individual GRKs are selectively targeted to GPCRs have been GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

dedicated to investigating how molecular changes at the nerve synapse might impact integrated behavior and what we might learn from these mechanisms to cure mental illness. CNRS as a Research Fellow in 1987 in the INSERM Laboratory directed by Jean-Charles Schwartz in Paris, where From 91 to 94, he was an assistant professor at Duke University in North Carolina, working with Marc Brunos Giros on the web The Douglas Research Centre McGill University Pubmed Google Scholar LinkedIn

These approaches were invaluable to resolve the crystal structure of the beta2-adrenergic receptor (beta2AR We continue to utilize these data to better understand the basis for receptor-G protein specificity and One example of our recent work surrounds a structure-based effort to develop ligands that specifically We also study non-canonical sites, those outside of the native hormone, or orthosteric, binding sites Roger Sunahara on the web UCSD Profile Google Scholar ResearchGate LinkedIn Dr.

He then completed his Ph.D. at Leeds as well as the University’s Ackroyd, Brotherton, and Brown Scholar the Receptor Biology Section at the Medical Research Council (MRC) -Human Reproductive Sciences Unit within his scientific journey with the award of the highly-valued Odysseus Program Type I Program Grant to work Stuart Maudsley on the web Maudsley Lab LinkedIn Google Scholar ResearchGate Maudsley Lab on Facebook Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

interests in research are primarily directed towards methods that study GPCRs and GPCR signaling, as well Eric Johansen on the web Johns Hopkins University Dr. Grace Mazarura on the web McGill University Dr. Émile Breault on the web Google Scholar ResearchGate Dr. Bassam Albraidy on the web X (Twitter) LinkedIn Dr.

completed her postdoctoral fellowship at UC San Francisco under the guidance of Professor Shaun Coughlin where she worked on the newly discovered protease-activated GPCRs. Carolina in 2000 and then moved to UC San Diego School Medicine, Department of Pharmacology in 2008, where JoAnn Trejo on the web UC San Diego Trejo Lab Wikipedia ​​​​LinkedIn Google Scholar Orcid Twitter UC Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

While the involvement of G-protein-coupled receptors (GPCRs) in cancer is growing, GPCR-based therapies Here, we demonstrate the overexpression of protease-activated receptor 2 (PAR2), a GPCR member in the We show now that knocking down Par2 inhibits ovarian cancer peritoneal dissemination in vivo, pointing Previously we identified pleckstrin homology (PH) binding domains within PAR1,2&4 as critical sites for GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Here, we find that GPR143, an atypical GPCR, controls the endosomal sorting complex required for the interacts with HRS (an ESCRT-0 Subunit) and promotes its association to cargo proteins, such as EGFR, which Through gain- and loss-of-function studies in mice, we show that GPR143 promotes metastasis by secreting Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

list Julia Gardner About Julia Gardner Julia is a senior undergraduate student at Duke University, where Julia has been working as a researcher in Duke's Rajagopal Lab since her first year as an undergraduate Last summer, Julia worked at as the first-ever summer intern at Septerna, the GPCR-based biotechnology Julia Gardner on the web Rajagopal Lab Google Scholar ResearchGate LinkedIn Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

In my role at Orion Biotechnology, I work at the intersection of science and business, which includes To that end, I'm grateful to be working alongside the very talented team at Orion who translate important GPCR research into novel therapies for patients. " Irfan Dhanidina on the web LinkedIn The Org DIBIZ While a postdoctoral fellow, Dr. Slosky’s work has been recognized through several travel and research awards, including the William James

Yamina Berchiche on the web Website LinkedIn Facebook Twitter ResearchGate PubMed Google Scholar Dr. work routines." Maria Waldhoer on the web LinkedIn T witter Pubmed Dr. GPCR About Dr. JoAnn Trejo "Dr. From 1987 to 1994, they were the Director of Biocomputing at The Salk Institute, where they managed institute-wide From 2002 to 2006, they were a Senior Application Scientist at Accelrys, where they were the technical

Caron at Duke University (1994-1997), where he and his colleagues investigated the role of G protein-coupled Stephen Ferguson on the web Carlton University Canada Research Chairs Twitter ResearchGate LinkedIn Dr Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

Here we reported the first comprehensive proteogenomic characterization of natural killer/T-cell lymphoma Authors Jie Xiong , Yu-Ting Dai , Wen-Fang Wang , Hao Zhang , Chao-Fu Wang , Tong Yin , Shu Cheng , Hui-Juan Zhong , Shan-He Yu , Lu Jiang , Sheng-Yue Wang , Hai Fang , Rui-Hong Zhang , Yue Zhu , Hong-Mei Yi , Xu-Feng Jiang , Jia-Yi Chen , Li Wang , Peng-Peng Xu , Sai-Juan Chen , Wei-Li Zhao Tags CCR1 , Epstein-Barr GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

In this study, we examined the role of VIPR2 in cell cycle progression. Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Katarzyna Marcinkiewicz "Katarzyna is a Senior Editor at Nature Communications, which she joined in April She obtained her Ph.D. from Weill Cornell Graduate School of Medical Sciences in New York City, studying Katarzyna Marcinkiewicz on the web LinkedIn Nature The Spectator Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

Elva moved to Canada where she obtained her Ph.D. at the University of Western Ontario, working on the After her Ph.D., she moved to Australia and continues working on GPCRs. Elva Zhao on the web LinkedIn Monash University Pubmed Twitter Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

William Cole at the University of Calgary in 2010 for his Ph.D. where he studied the molecular basis He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and Khaled Abdelrahman on the web University of British Columbia Twitter PubMed Google Scholar Dr.

He completed postdoctoral training at the Weizmann Institute. Jacobson on the web NIDDK Web of Science Google Scholar LinkedIn Twitter Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

He has successfully built numerous global life science, leadership teams, & works closely with both clients Mark believes professional placement should be about matching talented people with companies where they will thrive, “when the match is right, the results are astonishing.” Mark Schmeizl on the web Website LinkedIn Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode