Search Results
146 items found for "Kallikrein-related peptidases"
- 📰 GPCR Weekly News, February 26 to March 3, 2024
autophagy activation and inhibition of the PKA-Hippo signaling pathway Blockade of vasoactive intestinal peptide
- 📰 GPCR Weekly News, February 5 to 11, 2024
in Cardiology, Endocrinology, and Taste G protein-coupled receptors driven intestinal glucagon-like peptide
- Unlocking the Future of Medicine: Advancements in GPCR Research
quiescence and prevents stem cell loss Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide
- 📰 GPCR Weekly News, April 24 to 30, 2023
a panel discussion at the LSX World Congress Novel living yeast-based dual biosensor for detecting peptide
- A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in...
whichis alsooneofthemostcommonfemalereproductivesystemtumors, but there are few pieces of research related
- 📰 GPCR Weekly News, February 20 to 26, 2023
Gαi-derived peptide binds the µ-opioid receptor.
- 📰 GPCR Weekly News, February 12 to 18, 2024
GPCRs: the Gα-binding-and-activating (GBA) motif Mechanisms of biased agonism by Gαi/o-biased stapled peptide
- Molecular targets of psychedelic-induced plasticity
in human studies and contextualize them considering previous preclinical models studying phenomena related
- Role of G Protein-Coupled Receptors in Hepatic Stellate Cells and Approaches to Anti-Fibrotic ...
Gaining control over disease-related events in non-alcoholic steatohepatitis (NASH), an advanced form Therefore, a better understanding of the pathophysiology of hepatic fibrosis and the development of related
- 📰 GPCR Weekly News, October 2 to 8, 2023
in Neuroscience Involvement of a silkworm D2-like dopamine receptor in the promotion of feeding and related Depletion Using Statin Side-Chain Dynamics of the α1B -Adrenergic Receptor determined by NMR via Methyl Relaxation
- Illuminating GPCR Research: FRET and BRET-Based Sensors Shed Light on Cellular Signaling
., Activation of the GLP-1 receptor by a non-peptidic agonist.
- Posttranslational modifications in GPCR internalization
significance in GPCR internalization dynamics, internalization routes, postinternalization fates, and related
- Crinetics Pharmaceuticals Expands Executive Team With Appointment Of James Hassard As Chief ...
development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related
- Expression pattern and clinical significance of beta 2-adrenergic receptor in oral squamous cell...
The present study aimed at investigating the β2-AR gene expression and its significance in relation with
- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
The expression markers related to odontoblastic differentiation of hDPSCs were observed by qPCR and chemical
- Search for safer pain relief advances with new engineered compounds
opioid receptors, but without inducing many dangerous and unwanted side-effects that have driven opioid-related
- Interacting binding insights and conformational consequences of the differential activity of...
functional feature of CBD, that is, displaying antagonistic and (possible) agonistic ligand properties in related Here, using computational methods, we investigate the interacting determinants of CBD in two closely related
- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
, development and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related
- PLC-IP3-ORAI pathway participates in the activation of the MRGPRB2 receptor in mouse peritoneal...
mouse peritoneal mast cells "A novel mast cell-specific G-protein-coupled receptor (GPCR), known as Mas-related
- Domain Therapeutics and Explicyte enter partnership agreement in immuno-oncology
March 2022 "Explicyte grants Domain Therapeutics exclusivity on data related to GPCR implicated in immunoresistance
- Chronic itch: emerging treatments following new research concepts
However, many new targets, such as Mas-related GPCRs and unexpected new pathways need to be also explored
- Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand...
ligand specificity, and structural comparison between the activated GALR2 and inactive hβ2AR was used to relate
- Primary cilia and SHH signaling impairments in human and mouse models of Parkinson’s disease
Alterations in gene expression appear in pathways related to primary cilia (PC).
- The Gluopsins: Opsins without the Retinal Binding Lysine
The gluopsins are mainly dragonfly and butterfly opsins, closely related to the RGR-opsins and the retinochromes
- Rhodopsin as a Molecular Target to Mitigate Retinitis Pigmentosa
These disorders are mainly related to the abnormalities in the rod G protein-coupled receptor (GPCR),
- 📰 GPCR Weekly News, January 30 to February 5, 2023
Valorization of leftover green tea residues through conversion to bioactive peptides using probiotics-aided
- TRPM3 in the eye and in the nervous system - from new findings to novel mechanisms
Therefore, the newest data related to TRPM3 have to be discussed and to be put in context as soon as
- Although the cannabinoid type-2 receptor (CB2) is highly expressed in the immune system, emerging...
The development of new CB2-related pharmacological and genetic tools, including the first small molecule