Taste FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic

Inversago Pharma to develop new therapies for people living with obesity, diabetes and other serious metabolic

significant advantages in drug discovery, no single method can fully capture the impact of residue alterations Mutagenesis involves deliberately altering the DNA sequence of a gene to study the resulting changes

From a general overview, after GPCRs synthesis in the endoplasmic reticulum, GPCRs are transported to Phosphorylation state of muopioid receptor determines the alternative recycling of receptor via Rab4

September 2022 "RNA editing is a process by which post-transcriptional changes of mRNA nucleotides alter

GPCR Activation and Signaling Altered Signaling and Desensitization Responses in PTH1R Mutants Associated with Eiken Syndrome Antagonistic interactions between odorants alter human odor perception.

modulators of G protein-coupled-receptors (GPCRs), mechanistic understanding of how these modulators alter

Inversago Pharma Presents Data from Phase 1b Trial of INV-202, a Peripheral CB1r Blocker for Metabolic

GPCR Podcast features a recap of the Endocrine Metabolic GPCRs 2024 with the organizers, Drs.

This review focuses on the role of neuropeptides in maintaining the homeostasis of the ocular surface, alterations

The absence of VLGR1 in tissues and cells derived from VLGR1-deficient mouse models resulted in alterations

in GPCR Research High-throughput G protein-coupled receptor-based autocrine screening for secondary metabolite

outcomes in various primary and clonal cell systems, with even small changes in amino acid sequence altering

Olanzapine manipulates neuroactive signals and may onset metabolic disturbances.

substances at the serotonin receptor 5-HT2A R "Serotonergic psychedelics are substances that induce alterations

A key role for Gβγ subunit instead of cAMP Olanzapine manipulates neuroactive signals and may onset metabolic

that peptides derived from the transmembrane region of GPCRs can block the formation of dimers and alter example is a peptide derived from TM5/TM6 of the cannabinoid CB1 receptor (CB1R) which has been shown to alter

American Physiology Summit April 5 - 10, 2024 | AACR Annual Meeting April 22 - 23, 2024 | Endocrine Metabolic

autism spectrum disorders Systematic characterization of multi-omics landscape between gut microbial metabolites

In conclusion, 10μM THC and CBD altered the differentiation of HC11 cells, in part via the CB2 receptor

SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression

Drug Discovery Chemistry April 5 - 10, 2024 | AACR Annual Meeting NEW April 22 - 23, 2024 | Endocrine Metabolic

Circulating catecholamines (norepinephrine and epinephrine) and aldosterone elevations are among the salient alterations

However, GnIH peptides did not alter NFAT-RE-luc activity and ERK phosphorylation levels.

dietary restriction, those related to insulin signaling and the AMPK and TOR pathways, and those that alter

Nonetheless, we determined that mGlu5a internalization was not altered upon the loss of cPKCs or nPKCs

GPCR Binders, Drugs, and more Altered signaling at the PTH receptor via modified agonist contacts with Alterations in mouse visceral adipose tissue mRNA expression of islet G-protein-coupled receptor ligands

Endocrinology, and Taste G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic