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101 items found for "SCI-induced immunodeficiency syndrome"
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
These data indicate that Gαs-GPCRs are druggable immune checkpoints that might be targeted to enhance
- Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
In lung cancer to date, evidence indicates that KLK5, KLK6, KLK8, KLK11, and KLK14 are the major peptidases
- Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer
receptor-specific agonist enhances expression of GAL2 receptor, not only in PDAC-PDX but also in healthy tissue indicating
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
results suggested that GNAS mutations impact endocrinological features in acromegaly through GPCR pathway induction
- GPR15 expressed in T lymphocytes from RA patients is involved in leukocyte chemotaxis to the synovium
Recent evidence indicates that GPR15 may be associated with modulation of the chronic inflammatory response
- G protein-coupled estrogen receptor (GPER)/GPR30 forms a complex with the β1-adrenergic receptor, a membrane-associated guanylate kinase (MAGUK) scaffold protein, and protein kinase A anchoring protein (AKAP) 5 in MCF7 breast cancer cells
Deleting the GPR30 C-terminal PDZ motif (-SSAV) does not interfere with the receptor complex, indicating
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
Given the cell and tissue-specific expression of different Gγ subtypes, our findings indicate a plausible
- Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
2024 Abstract "Studying primordial events in cancer is pivotal for identifying predictive molecular indicators
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
Conclusion: Our findings indicate that RGS20 drives NSCLC cell proliferation by triggering autophagy
- Receptor autoantibodies: Associations with cardiac markers, histology, and function in human non-ischaemic heart failure
for total IgG. β1 AR autoantibodies were related inversely to markers of left ventricular fibrosis indicated
- Session VII | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
through RNA interference, show a higher nocifensive response compared to wildtype remorescue controls indicating
- GPCR Retreat 2023 - Part I
interested in peptide/small protein receptors and the mechanisms that facilitate their role in various indications
- Ep 142 with Dr Claudia Stäubert
Yamina also pointed out that Claudia was their first guest of the year, indicating the start of a new
- Trademark Policy | Dr. GPCR Ecosystem
GPCR Brand Features must be accompanied by a notice that clearly indicates that the Dr. After clicking the button, the user indicates to follow that Publisher. - Dr.
- Ep 152 with Dr Arthur Christopoulos
Yamina appreciated Arthur's expertise and indicated she would be creating an outline for an episode on
- Ep 144 with Dr Aurélien Rizk
Aurelien Rizk shared that he had always focused on GPCRs but had also worked on other types of receptors, indicating
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