Treatments include surgical resection, radiotherapy, and chemotherapy. Despite this, the prognosis remains poor, with an impacted quality of life during treatment coupled with brain tumour recurrence; thus, new treatments are desperately needed.

Alzheimer's disease (AD) is the most common dementia in the elderly and its increasing prevalence presents treatment Despite a better understanding of the disease, the current mainstay of treatment cannot modify pathogenesis

Alzheimer's disease (AD) is the most common dementia in the elderly and its increasing prevalence presents treatment Despite a better understanding of the disease, the current mainstay of treatment cannot modify pathogenesis

This review discusses the specific tissue expression of the components of the chemerin system, and the

with the β-arrestin1 N-lobe, in agreement with structural data obtained with chimeric or synthetic systems

October 2022 "Understanding the dopaminergic system is a priority in neurobiology and neuropharmacology

focused on the development and commercialization of novel medicines for patients with central nervous system

adenylyl cyclase (AC) Rv1625c/Cya is an evolutionary ancestor of the mammalian membrane ACs and a model system

Herein, we identified GPR108, a GPCR protein described in innate immune system, is a potential therapeutic

October 2022 "The role of different G protein-coupled receptors (GPCRs) in the cardiovascular system

class C G protein-coupled receptor (GPCR) heterodimer, plays a crucial role in the central nervous system

the G-protein interface "Galanin is a neuropeptide expressed in the central and peripheral nervous systems

antibody fragments from camelids, have become indispensable tools for interrogating GPCRs both in purified systems

considered promising agents to treat Parkinson's disease, inflammation, cancer, and central nervous system

dysbiosis and bacterial infection "Healthy skin maintains a diverse microbiome and a potent immune system

The molecular mechanisms N. meningitidis employ to manipulate the immune system, translocate the mucosal

conditions such as Alzheimer's disease and multiple sclerosis, in the recovery from central nervous system

Despite major advances in the field of pharmacological CVD treatments, particularly in the field of heart Currently-approved treatments have improved patient outcomes, but therapies to stop or reverse HF are

S1P5 is predominantly expressed in nervous and immune systems, regulating the egress of natural killer

December 2021 "Early-stage studies of COVID-19 treatments from the likes of Vir Biotechnology Inc. and omicron strain of the virus was first identified in South Africa in early November, and an existing treatment

using live-imaging modalities, and displayed high efficiency when used to label complex 3D cellular systems

Radionetics aims to develop a deep pipeline of novel, targeted, nonpeptide radiopharmaceuticals for the treatment Radionetics aims to develop a deep pipeline of novel, targeted, nonpeptide radiopharmaceuticals for the treatment

support the idea of a modulatory role of anosmin 1 in the biological effects controlled by the PK2/PKR2 system

This personalised approach could optimise drug efficacy while minimising adverse effects, improving treatment These insights have the potential to advance the treatment of various diseases involving GPCR signalling

proinflammatory glycoproteins liberated by the activation of the biochemical cascade of the complement system

United States Food and Drug Administration's designation of psilocybin as a "Breakthrough Therapy" for treatment-resistant

In the prospect of a psychedelic drug becoming again an approved treatment, much of these efforts have

Proliferation, migration and apoptosis assays were performed in ovarian cancer cells after fentanyl treatment