Search Results
160 items found for "Targeted therapy"
- Ep 151 with Dr GPCR Board
in using G-Protein Coupled Receptors (GPCRs) that control virtually everything in the body as drug targets important for increasing the fundamental knowledge of GPCR biology and for the identification of drug targets has important functions in hemostasis, thrombosis, inflammation, and cancer and is an important drug target
- Ep 13 with Dr. Amynah Pradhan
Charles that who specialized in animal models of migraine and delta-opioid receptors as a therapeutic target
- Ep 79 with Dr. Graeme Milligan
His experience also includes translating knowledge generated into the selection of targets, screening
- Ep 157 with Dr. Nagarajan Vaidehi
advanced the use of computational methods to meet the challenges of designing therapeutics with lower off target
- Developing a PROTAC to Degrade the Constitutively Active Onco-GPCR in Uveal Melanoma
signaling and degradation of GPCRs in disease states to help test the feasibility of using protein-targeted
- Ep 63 with Dr. Khaled Abdelrahman
as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can be targeted
- Ep 16 with Dr. Aaron Sato
scale, the team saw an opportunity to tackle the challenge of identifying novel functional antibodies targeting
- Ep 59 with Dr. Nicola J. Smith
GPCRs from ‘locked’, inaccessible receptors to well-characterized and understood ‘unlocked’ therapeutic targets
- Ep 34 with Dr. Brian Arey
He continues to pioneer in drug discovery studying GPCRs and other target classes.
- Ep 35 with Dr. Brian Arey
He continues to pioneer in drug discovery studying GPCRs and other target classes.
- Ep 51 with Dr. Mark Connor
pharmacology of phytocannabinoids and novel synthetic cannabinoids, with a focus on efficacy and novel targets
- Ep 61 with About Dr. Marta Filizola
the structure, dynamics, and function of important classes of membrane proteins and prominent drug targets
- Itaconate in host inflammation and defense
In this article, we review ITA metabolism and its regulation, discuss its target proteins and mechanisms
- Ep 37 with Dr. Samuel Hoare
Sam about his love for GPCRs, kinetics, and decorticate the complexities of GPCR function to better target
- Ep 56 with Dr. Adriano Marchese
The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic
- Ep 62 with Dr. Sai Prasad Pydi
The main target of Dr.
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
TACR3), a homolog of the G protein-coupled receptor TkR99D in fruit flies, as a potential therapeutic target
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
as a Postdoctoral Fellow to explore novel G protein-coupled receptor (GPCR) candidates that can be targeted
- Ep 18 with Dr. Yamina Berchiche
opportunities, weaknesses, and advantages of these new technologies, which may contribute to probe our favorite targets
- Ep 109 with Dr. Katarina Nemec
I aim to discover new therapeutic approaches, and druggable molecules or refine canonical drug targets
- Role and recent progress of P2Y12 receptor in cancer development
Meanwhile, P2Y12R inhibitors can inhibit this effect, suggesting that P2Y12R may be a potential therapeutic target
- Ep 90 with Dr. Nariman Balenga
fungal serine protease allergen with GPCR-modulating features was discovered as a new biomarker and target
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
of CXCR2 small molecule antagonists, we speculated that CXCR2 can be used as a biomarker and a new target
- Ep 98 with Dr. GPCR Team
in using G-Protein Coupled Receptors (GPCRs), that control virtually everything in the body, as drug targets
- Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
CRISPR/Cas9 targeting of PAR1 and PAR2 combined with microarray analysis revealed genes that are regulated
- High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma cells in vitro
CCT6A-induced proliferation and PGK1-induced migration and autophagy, and GPR50 could be an important target
- Ep 95 with Chris Langmead
Discovery Centre at the Monash Institute of Pharmaceutical Sciences (MIPS), a collaborative venture targeting
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