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Development DKK 25 million to development of databases supporting medical research ‘Define your own success’: Duke

selectivity and allosteric probe dependence at Hydroxycarboxylic acid receptor HCAR2 Antipsychotic displays dual Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting

in Cardiology, Endocrinology, and Taste Structural and functional analysis of salivary intercalated duct Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting

., Dukkipati, A., Feinberg, E. N., Angelini, A., Waghray, D., Dror, R. O., Ploegh, H.

Robert Lefkowitz on his 50 years at Duke. Congratulations. Dr. basis of GPR84 signaling Structural diversity of leukotriene G-protein coupled receptors Industry News Duke Lefkowitz's Career at Duke October 3, 2023, | FREE Seminar: Changing paradigm on Therapeutics targeting

Emerging Cannabinoid Analogs GPCRs in Neuroscience Serotonin signaling regulates actomyosin contractility during

Immunology Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant Neuroimmune interplay during

Randy Hall's study: GPR37L1's role in shaping cortical astrocytes during development Dr. activating GHS-R1a/D2R heterodimers GPR37L1 controls maturation and organization of cortical astrocytes during

Adhesion GPCRs Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion

Structural and Molecular Insights into GPCR Function Dual mechanisms of cholesterol-GPCR interactions

Differential Responses of the GLP-1 and GLP-2 Receptors to N-Terminal Modification of a Dual Agonist.

Pharmaceuticals Announces Positive Phase 3 Results Showing Mavorixafor Reduced the Rate, Severity, and Duration

Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with Biotechnology will be participating in a panel discussion at the LSX World Congress Novel living yeast-based dual

GPR37L1 controls maturation and organization of cortical astrocytes during development.

hypomineralization in mice by alteration of the expression of kallikrein-related peptidase 4 (Klk4) during

The immunometabolite itaconate stimulates OXGR1 to promote mucociliary clearance during the pulmonary

GPCR Activation and Signaling The dual-function chemokine receptor CCR2 drives migration and chemokine Comparative evaluation of biased agonists Sarcosine1 , d-Alanine8 -Angiotensin (Ang) II (SD Ang II) and Sarcosine1 , Isoleucine8 -Ang II (SI Ang II) and their radioiodinated congeners binding to rat liver

Due to the diversity of the OR family it will be critical to select potential targets to modulate in

Interestingly, the amplitude of the conformational changes due to ligand binding is limited at these

proteins and to regulate various cellular processes, including glycogenolysis.[33–39] In their work, the duo

Therefore, we wondered: Do opsins exists that have lost this lysine during evolution?

The cleavage appears to occur at an atypical GPCR proteolysis site within the GAIN domain during an early Consistent with the multilumen phenotype, mitotic spindles are incorrectly oriented during cystogenesis

cannabis use among pregnant women has presented an urgent need to investigate its physiological effects during During pregnancy, the mammary gland (MG) undergoes remodeling, which involves alveolar differentiation

Using array-based comparative genomic hybridization (array-CGH), we identified two CNVs, both triplex duplications

The careful structural modifications during the lead optimization phase led to a compound with high biological

phosphorylated glycogen phosphorylase under hypoglycemia and that of phosphorylated glycogen synthase during

protein-coupled receptors (GPCRs) is of paramount importance to the field of cardiovascular medicine due Nanobodies have gained traction rapidly due to their biochemical tractability and their ability to recognize

of heterotrimeric G protein signaling upon ligand binding occurs solely at the cell surface and that duration