neurotransmitters and how they might underlie brain and behavior disorders such as schizophrenia, Parkinson's disease

This may help to develop more potent ligands for the treatment of inflammatory related diseases."

, molecular and cellular pharmacology, medicinal chemistry, and preclinical models of behaviour and disease work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular disease Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with

, molecular and cellular pharmacology, medicinal chemistry, and preclinical models of behaviour and disease work has been applied to studies encompassing neurological and psychiatric disorders, cardiovascular disease Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with

expressed NPFF, these findings could have broad implications in various infectious and inflammatory diseases

laboratory has gained valuable insights into the genetic basis and pathophysiology of lymphatic vascular disease , preeclampsia and sex-dependent cardiovascular disease.

Our laboratory is working to help patients by developing genetically-modified mice that have disease-causing

small molecules can selectively disable noncanonical mechanisms of G-protein activation dysregulated in disease

were shown to be very effective to rescue the cell death observed in a mouse model of Huntington’s disease

Despite advances in the treatment, many patients experience disease relapse or become refractory to treatment

essential in regulating GPCR signaling, and most members are implicated as critical nodes in human diseases

Exosomes transport a variety of macromolecules and modulate intercellular communication in physiology and disease

Conclusions: Antagonizing the NPYRs has been implicated as a treatment for a wide variety of diseases

where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease

where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease

cancer Published date June 24, 2024 Abstract "Pancreatic ductal adenocarcinoma (PDAC) remains a dreadful disease

the C5aR1, which has received enormous attention for its role in both acute and chronic inflammatory diseases

where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease

Randy’s lab has a special interest in studying disease-associated mutations to human GPCRs that perturb

where he remained until 2018 studying GPCRs and their signaling pathways in the liver and in liver disease

Initial impairment of synaptic functions, which occurs early in Alzheimer’s disease, and subsequent massive My research focus is the mechanisms of neural circuit development, function and disease."

prenylation contributes to multiple disorders, including cancers and vascular and neurodegenerative diseases

Published date November 3, 2023 Abstract " Purpose: Peripheral T-cell lymphoma (PTCL) is an aggressive disease

Published date November 1, 2022 Abstract Pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease

primarily due to the lack of early diagnostic tools, effective targeted therapy, and clear understanding of disease

indicated that beclomethasone dipropionate (BDP), an agonist of GPR97, attenuated the psoriasis-like skin disease

there was not much known other than that they are huge and somehow play important roles in health and disease

Patients with ERα-positive/PR-negative tumors have shorter disease-free and overall survival than patients