Search Results
131 items found for "immune response"
- Ep 38 with Dr. Alexander S. Hauser
Molecular Biology in Cambridge, UK, where he was working on the impact of genetic variations on drug response
- Ep 64 with Dylan Eiger
phosphorylation (phosphorylation barcodes) and subcellular GPCR signaling in directing functionally selective responses
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
develop new precision cancer treatments, and to identify novel multimodal strategies to enhance the response
- Ep 35 with Dr. Brian Arey
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility
- Ep 34 with Dr. Brian Arey
He then moved to work in the pharmaceutical industry where he has held positions of increasing responsibility
- Ep 16 with Dr. Aaron Sato
His path led him to work in an industry where he assumed various responsibilities and roles in the antibody
- Ep 150 with Dr GPCR Team
past two decades studying structure/function relationships of GPCRs using live-cell bioluminescence resonance As a young researcher fascinated by chemokine receptors, molecular pharmacology, drug discovery, and immuno-oncology
- Ep 31 with Dr. Kevin Pfleger
He also has globally-recognized expertise in bioluminescence resonance energy transfer (BRET) technology Join me and learn more about Kevin’s work and how he manages all his responsibilities. Dr.
- Ep 136 with Murat Tunaboylu & Ben Holland
Following this, he joined an early-stage medical device start-up and in 5 years was responsible for project
- Noval insights and therapeutic strategies for tumor-induced kidney pathologies
significance of TACR3 and provided an in-depth analysis of cell type specific expression of TACR3 in response
- Travel Tips for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Airfare and other travel arrangements are the full responsibility of aGPCR Workshop 2024 attendees. POSTER PRINTING Poster printing is the full responsibility of aGPCR Workshop 2024 attendees.
- Ep 95 with Chris Langmead
., a UK-based biotechnology company (2009-2012), where he was responsible all of the company’s discovery
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
favoring an alternative-like polarization, suggesting that it may act to balance overzealous neutrophilic responses
- Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology
underlying mechanisms of food reward and its downstream dysregulation of metabolic function, particularly in response
- Ep 113 with Dr. Prasenjit Saha
pursuit of allosteric modulators has gained attention as they have the potential to fine-tune cellular responses
- Ep 132 with Dr. Richard Premont
distinct cellular signaling pathways interact and are coordinated to produce integrated physiological responses
- Ep 130 with Dr. Richard Premont
distinct cellular signaling pathways interact and are coordinated to produce integrated physiological responses
- Ep 54 with Dr. JoAnn Trejo
signaling is critical for proper temporal and spatial dynamics of signaling and appropriate cellular responses
- Ep 133 with Dr. Richard Premont
distinct cellular signaling pathways interact and are coordinated to produce integrated physiological responses
- Ep 131 with Dr. Richard Premont
distinct cellular signaling pathways interact and are coordinated to produce integrated physiological responses
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
excessive deposition of extracellular matrix proteins, particularly collagen, caused by myofibroblasts in response
- Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
There were some discrepancies in the responses of each cell line to the isoform-specific antagonists
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
Our results also showed that ERK1/2 signaling was activated in SKOV3 cells in response to the NPFF treatment
- Trainee Symposium I
research project I use iPSC-derived cardiac fibroblasts to examine cellular signaling in the fibrotic response
- Advanced data analysis for GPCR pharmacology | Dr. GPCR Ecosystem
Modules: Module 1 - Concentration-response analysis: Become a CRC super-user.
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
UCA1 expression inversely correlates with survival outcomes and therapy response in ovarian cancer clinical
- Vasoactive intestinal peptide receptor 2 signaling promotes breast cancer cell proliferation by enhancing the ERK pathway
Additionally, phosphorylation of vasodilator-stimulated phosphoprotein (Ser157) and cAMP response element
- Ep 144 with Dr Aurélien Rizk
conversation concluded with Yamina asking if Aurelien Rizk had a favorite GPCR to work on, though his response Yamina shared her research experience, emphasizing the fascination of understanding how cells respond