Search Results
117 items found for "Cam Sinh Lu"
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Either GRK2 or HDAC inhibition prevented loss of mouse lung bacterial clearance, but only the combination
- Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated TGFβ2 activation
Transforming growth factor-β (TGFβ) is essential for alveologenesis and lung repair, and the G protein To understand the role of mesenchymal Gαq/11 in lung development, we generated constitutive (Pdgfrb-Cre suppressed myofibroblast differentiation, altered mesenchymal cell synthetic function, and reduced lung TGFβ2 signalling in mesenchymal cells, which is imperative for normal alveologenesis and maintenance of lung Tags Alveologenesis , Cyclical mechanical stretch , GPCR , Gαq/11 , Lung development , TGFβ .
- Ep 60 with Dr. Josephine (Pina) Cardarelli
project, licensed to AstraZeneca (Saphnelo™ Anifrolumab) that has just received FDA approval for systemic lupus
- Ep 148 with Dr Arthur Christopoulos
Since 2014, Clarivate Analytics have annually named him a Highly Cited Researcher in ‘Pharmacology &
- Ep 149 with Dr Arthur Christopoulos
Since 2014, Clarivate Analytics have annually named him a Highly Cited Researcher in ‘Pharmacology &