GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in G protein-coupled Methods & Updates in GPCR Research 3,4-Bis(hydroxymethyl)hexane-1,6-diol-based Maltosides (HDMs) for

exceptional professors' ability to simplify the complexity of GPCR pharmacology and apply it to their research Regulating Hunger and Satiety OMass Therapeutics Expands Development Team with Key Appointments in US and UK Europe July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs HIGHLIGHT Research Scientist, Computational Chemistry Postdoc in GPCR mechanosensing   Postdoctoral Position Postdoctoral research protein coupled receptor transcripts in human immune cells and platelets Methods & Updates in GPCR Research

Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression Methods & Updates in GPCR Research GPCRLigNet: rapid screening for GPCR active ligands using machine Bioinformatics/Data Science at Department of Drug Design and Pharmacology Scientist/Senior Scientist (Research

focused on orally administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer

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targets and advance the development of new gastrointestinal therapeutics Tokyo, Japan, Cambridge, UK City-based Kallyope , pioneers in drug discovery involving the gut-brain axis, have entered a strategic research

Yamina Berchiche at the Endocrine Metabolic GPCRs event in Birmingham, UK, on April 22-23, 2024. migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Senior Scientist- Internal Medicine Research NEW Postdoctoral Scholar – Synaptic physiology, optical imaging, substance use disorder, pharmacology Research - Single-molecule Imaging Center Scientific Assistant Postdoctoral Fellowship- Mechanistic Biology Research

The research team, led by Brandon Novy and colleagues, utilized an innovative APEX2/AUR biosensor that By employing this biosensor, the research team identified 492 genes that significantly influence DOR After the labeling reaction, the researchers purified and biotinylated proteins (those that have been As the opioid crisis continues to challenge public health, insights gained from this research could inform The implications of this research extend beyond basic science ; understanding the role of DNAJC13 in

multiple roles in the pathological mechanisms of a wide range of diseases including heart failure, cancer

of Heydenreich et al. (2023) will be analysed to demonstrate how mutagenesis can be employed in GPCR research Through an in-depth mutational analysis of β2AR, the researchers identified specific residues that influence This case study underscores the critical importance of mutagenesis in GPCR research. Rational Drug Design One immediate application of this research lies in rational drug design . By identifying key β2AR residues that influence efficacy and potency, pharmaceutical researchers can

Check out our latest coverage of GPCRs this week, featuring 15 insightful research papers and industry Stay informed with the latest GPCR research and industry news. Nicola J Smith, Lauren T May, and Natasha L Grimsey for their work on Highlights and hot topics in GPCR research Join the global GPCR community and share your research—submit your abstract using this form. Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.

highlight: Congrats to our partner GPCR Therapeutics, on their expansion into fibrosis with their new research -like dopamine receptor in the promotion of feeding and related behaviors Methods & Updates in GPCR Research Scientist In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist (level I or II) Research Fellow Research Technician II - Surgery Post-Doc Research Associate Research Technician Explore Dr.

has been implicated in a range of diseases, including cardiovascular disease, pain, hypertension, and cancer While in cancer, RGS proteins are involved in regulating cell proliferation and survival[8]. al., Identification of a five-gene signature of the RGS gene family with prognostic value in ovarian cancer

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exclusivity on data related to GPCR implicated in immunoresistance, to develop first-in class innovative cancer

For instance, aberrant endosomal signaling by GPCRs has been linked to disorders such as cancer, neurodegenerative Neurochemical research, 42(1), 166–172. https://doi.org/10.1007/s11064-016-2026-6 Mendizabal-Zubiaga, GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic

Hébert and their colleagues research on 'G Protein-Biased Agonists for Intracellular Angiotensin Receptors work on 'Molecular insights into orphan GPCRs relevant to schizophrenia' Carole Daly and their team research / Senior Researcher in Structural Biology NEW Research Specialist NEW Science Research Writer Postdoctoral Fellow Research Laboratory Specialist Associate Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular Pharmacology Explore Dr.

Graeme Milligan and their colleagues research on Pro-phagocytic function and structural basis of GPR84 Years of Scientific Discovery Novo Nordisk Foundation Grants Fuel Exciting GPCR and Signaling Protein Research | SLAS Europe 2024 Conference and Exhibition June 2 - 4, 2024 | Chemotactic Cytokines GPCR Jobs NEW Research Technician II - Surgery NEW Post-Doc Research Associate NEW Research Technician Senior Research Associate / Senior Researcher in Structural Biology Research Specialist Explore Dr.

Since then, the National Human Genome Research Institute (NHGRI) has supported annual events across the country to celebrate, learn and discuss the latest advances in genomic research. This intersection of genomics and GPCR research sparked a new era of a comprehensive understanding of References National Human Genome Research Institute, U. S. (2002) National Human Genome Research Institute.

GPCRs in Oncology and Immunology GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer Methods & Updates in GPCR Research Time- and cost-efficient bacterial expression and purification of

have been developed, with a focus on small molecules and monoclonal antibodies for the treatment of cancer

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everyone, Take a moment to explore our latest coverage of GPCRs this week, which includes 7 insightful research Stay informed with the most recent developments in GPCR research and industry news. Present Your Research: Submit your abstract by June 24th for priority consideration or by July 22nd for receptor-mediated synaptic depression in dorsolateral striatum of adult male mice Methods & Updates in GPCR Research Scientist, In vitro pharmacology Senior Scientist - Receptor Pharmacology Postdoctoral Scientist Senior Research

receptor (A2AAR) have been considered promising agents to treat Parkinson's disease, inflammation, cancer

We've got 15 insightful GPCR research papers and updates from the industry. Stay informed and up to date with the latest GPCR research and industry news. is a key regulator of receptor signaling Jiankun Lyu, Brian Shoichet, Bryan Roth, et al. for their research Get ready to share your research with the global GPCR community! Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Join Dr.

Matthew Eddy and lab research on GPCR signaling mechanisms using NMR spectroscopy with labeled receptors metabolites and a mechanistic link to microbiome-immune-brain interactions Methods & Updates in GPCR Research Scientist NEW In Vitro Biologist/Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist (level I or II) Research Fellow Research Technician II - Surgery Post-Doc Research Associate Research Technician Explore Dr.

latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity Norton Cheng, JoAnn Trejo, et al. for their research Submit a few slides for a poster presentation to showcase your research and network with our community Fellow Postdoc Position Principal Scientist, In vitro pharmacology Senior Associate Scientist - Global Research Technologies Novo Nordisk Scientist I - Global Research Technologies Novo Nordisk Postdoctoral Associate Research Technologist I Senior Scientist- Internal Medicine Research Unit Postdoctoral Scholar – Synaptic

receptors (aGPCRs)-a major family of GPCRs-play critical roles in the regulation of tissue development and cancer