In turn, due to overexpression of GPCRs on the surface of various types of cells, GPCR ligands can endow nanoparticles with active targeting capacity for specific cells via ligand-receptor binding and mediate transduction Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

receptors in the central nervous system and one of the key proteins for signal transduction between cells J Lawrence Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity Alejandra Tomas is a molecular cell biologist and Senior Lecturer at the Department of Metabolism, Digestion several years in Switzerland working on the study of membrane trafficking processes in pancreatic beta cells

the orphan atypical cannabinoid receptor, GPR55 and its crosstalk with CB1R and CB2R in endothelial cells which I characterized the impact of a fungal allergenic source on the function of airway smooth muscle cells

FRET and single-molecule microscopy, which allow them to directly observe signalling events in living cells Davide’s work has been published in prestigious scientific journals such as Nature, Cell, New England

These might serve as allosteric agonists of PAR1 on endothelial cells and platelets, and thus might contribute Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

co-founder of InterAx Biotech, where he specializes in the development of a technology platform deciphering cell explored the potential of merging mathematical models with biology, the complexities of GPCRs within cells Cell Signaling and Cancer Metastasis Discussion Aurelien Rizk and Yamina Berchiche had a detailed conversation about the intricacies of cell signaling and chemokine receptors. Yamina shared her research experience, emphasizing the fascination of understanding how cells respond

emphasizing the structural and evolutionary significance of TACR3 and provided an in-depth analysis of cell Chao Zhang Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Our laboratory is interested in the role of NMDA receptors not only on neurons, but also on other cells of the brain such as astrocytes, oligodendrocytes, and endothelial cells.

P2Y12R activation can promote platelet aggregation and adhesion to cancer cells, promote tumor angiogenesis microenvironment Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive

Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the After a well needed break from the grind, I am now a scientific/business consultant for clients both Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells

, 2023 Abstract "Macrophages release soluble mediators following efferocytic clearance of apoptotic cells macrophage Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

interactions are highly relevant for its different physiological effects, e. g. the migration of immune cells Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic endothelial cells

She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience

Simone Prömel Simone Prömel is currently a professor of cell biology at the Heinrich Heine University of action of Adhesion GPCRs and found that they do not only mediate classical G protein signals into cells

Group 2 innate lymphoid cells (ILC2s) play a critical role in maintaining adipose homeostasis via the resistance Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

The precise mechanisms by which ACs contribute to cancer cell proliferation and invasion are not well Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico.

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University

moved to Mexico City to establish himself as an independent investigator integrating the department of Cell as various alternatively spliced isoforms thus potentially resulting in differential modulation of cell

for a randomised controlled trial (RCT), including sham apheresis, and for an RCT combining IA with B-cell post-COVID syndrome Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

Among the five somatostatin receptors, SST2 and SST3 are associated with apoptosis and cell cycle arrest Michel Afargan Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

transcriptomic, proteomic, and phosphoproteomic differential expression data of GPR56 knockdown U373-GBM cells Signaling , TG2 Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

His studies led to new concepts in the GPCR field, such as the activation of cell surface receptors by

Protein-Coupled Receptors Cheng-Chih Hsiao ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells compact multidomain module of fourteen domains which regulates signaling Vasiliki Karagiannakou A single cell Axons Monserrat Avila Zozaya The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell GPR116 Willem Berend Post The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Role Of CELSR1 (ADGRC1) In Breast Cancer Emmanouil Kyrloglou GPR124 Mediates Adhesion Of Leukemic Stem Cells