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Authors Jing Gao, Huiqing Liu, Yuxin Jin, Yunbo Luo, Kunlun Huang, Zhihong Liang Tags Cell communication

In gene expression analysis of mouse lungs with induced fibrosis, eight GPCRs were identified, showing actin (αSMA), the profibrotic factor transforming growth factor β1 (TGFβ1), and collagen in a human lung Similar to the lung fibrosis model, increased Gpr176 expression was also observed in other organs affected expressed Gpr176 compared to alveolar epithelial cells, endothelial cells, and macrophages in the fibrotic lung

Authors Hsuan Lung, Kelly L Wentworth, Tania Moody, Ariane Zamarioli, Apsara Ram, Gauri Ganesh, Misun

Kussmaulallee 12, 91054 Erlangen, Germany 2 Developmental Genetics, Max-Planck-Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany 3 Department of Developmental Biology, Washington Immunoblots on wild-type and Adgrb1 exon 2-deleted mice, reverse transcription PCR and promoter-luciferase We previously demonstrated that kidney-specific Adgrf5/Gpr116 knockout causes luminal membrane accumulation James Bridges at National Jewish Health in Denver, CO researching molecular mechanisms of lung injury

Such pro-inflammatory immune cells may travel to tissues such as the brain, the lung, the kidney etc

Authors Kathrine Lundø , Oksana Dmytriyeva , Louise Spøhr , Eliana Goncalves-Alves , Jiayi Yao , Laia

Julia Tutzauer , D Stephen Serafin , Tobias Schmidt , Björn Olde , Kathleen M Caron , L M Fredrik Leeb-Lundberg

multimeric complexes larger than dimers in MDA-MB-231 human breast cancer cells and in HCC4006 human lung

Transforming growth factor-β (TGFβ) is essential for alveologenesis and lung repair, and the G protein To understand the role of mesenchymal Gαq/11 in lung development, we generated constitutive (Pdgfrb-Cre suppressed myofibroblast differentiation, altered mesenchymal cell synthetic function, and reduced lung TGFβ2 signalling in mesenchymal cells, which is imperative for normal alveologenesis and maintenance of lung Tags Alveologenesis , Cyclical mechanical stretch , GPCR , Gαq/11 , Lung development , TGFβ .

Mesothelioma and lung cancer induced by exposure to carcinogenic (e.g., certain asbestos) fibers in humans This theory is reviewed, implications of this theory are discussed in relation to mesothelioma and lung Author Kenneth T Bogen Tags Asbestos , Cytotoxicity , Inflammation , Lung cancer , Mesothelioma , Mutation

Authors Yue Xu, Zihan Quan, Yuting Zhan, Haihua Wang, Jiadi Luo, Weiyuan Wang, Songqing Fan Tags biomarkers

be used as a biomarker and a new target for diabetes and that CXCR2 antagonists may also attenuate lung