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467 items found for "GPCR therapeutics"

  • GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment

    < GPCR News < GPCRs in Oncology and Immunology GPR68-ATF4 signaling is a novel prosurvival pathway in These findings provide a promising therapeutic approach to selectively induce ferroptosis in glioblastoma News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • miR-19a may function as a biomarker of oral squamous cell carcinoma (OSCC) by regulating the signaling pathway of miR-19a/GRK6/GPCRs/PKC in a Chinese population

    < GPCR News < GPCRs in Oncology and Immunology miR-19a may function as a biomarker of oral squamous cell GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience insights into GPCR function GPCR Activation and Signaling More from Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Registration & Coffee with light breakfast | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program

  • Coffee Break with lights snacks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program

  • NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling

    < GPCR News < GPCRs in Oncology and Immunology NPFF stimulates human ovarian cancer cell invasion by News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice

    < GPCR News < GPCRs in Oncology and Immunology Regulator of G protein signaling protein 6 alleviates Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • The binding mechanism of an anti-multiple myeloma antibody to the human GPRC5D homodimer

    Its high expression on the surface of multiple myeloma cells has rendered it an attractive target for therapeutic Despite its therapeutic potential, the insufficient understanding regarding of the receptor's structure and antibody recognition mechanism has impeded the progress of effective therapeutic development. GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Board meeting/General assembly | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program

  • Booklet for participants | Dr. GPCR Ecosystem

    OFFICIAL BOOKLET Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF

  • From odor to oncology: non-canonical odorant receptors in cancer

    These findings shed light on the potential of non-canonical odorant receptors as therapeutic targets these chemoreceptors and various types of cancer, potentially paving the way for innovative odor-based therapeutics Ultimately, this review discusses the potential development of novel therapeutic strategies targeting a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and

  • Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy

    The potential for precise tumor diagnosis and targeted therapy through therapeutic targeting of olfactory Tang, Ye Tian, Chun-Xia Zhang, Guo-Tai Wang Tags G Protein-coupled receptors , Olfactory receptors , Therapeutic Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology

  • Transcriptomic analysis of human cytomegalovirus to survey the indirect effects on renal transplant recipients

    < GPCR News < GPCRs in Oncology and Immunology Transcriptomic analysis of human cytomegalovirus to survey Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling

    cancer (CRC) remains a major global cause of cancer-related mortality, lacking effective biomarkers and therapeutic Revealing the critical pathogenic factors of CRC and the underlying mechanisms would offer potential therapeutic proteins in CRC, identifying Regulator of G protein signaling 16 (RGS16) as a prospective diagnostic and therapeutic GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus

    Moreover, we utilize a combination of ex vivo and in vivo approaches to explore the functional and therapeutic Our mechanistic studies reveal that the therapeutic effects of CB2 are mediated through activation of News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Be Our Guest | Dr. GPCR Ecosystem

    career trajectory, discoveries, and how their research contributed to the shared pool of knowledge about GPCR

  • Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy

    This review explores e-ATP metabolism, its purinergic signaling, and therapeutic strategies targeting Tags Extracellular ATP (e-ATP) , Immunosuppression , Purinergic receptors , Purinergic signaling , Therapeutic Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Itaconate in host inflammation and defense

    < GPCR News < GPCRs in Oncology and Immunology Itaconate in host inflammation and defense Published date regulation, discuss its target proteins and mechanisms, and conjecture a rationale for developing ITA-based therapeutics News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy

    < GPCR News < GPCRs in Oncology and Immunology Opposite Effects of Src Family Kinases on YAP and ERK As therapeutic options are limited, novel targets, and agents for therapeutic intervention are urgently News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Chemoattractant receptor signaling in humoral immunity

    < GPCR News < GPCRs in Oncology and Immunology Chemoattractant receptor signaling in humoral immunity signaling in the context of humoral immunity and discuss the potential of the COMMD3/8 complex as a therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • Role and recent progress of P2Y12 receptor in cancer development

    Meanwhile, P2Y12R inhibitors can inhibit this effect, suggesting that P2Y12R may be a potential therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis

    < GPCR News < GPCRs in Oncology and Immunology GPR37 promotes colorectal cancer against ferroptosis by pro-carcinogenic effect of GPR37 in primary CRC and suggest that targeting GPR37 could be a potential therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

  • "Have a nice weekend, and I'll see you tomorrow!": RAMP-interacting GPCR Pathways

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to : RAMP-interacting GPCR Pathways Date & Time Thursday, November 2nd / 4:30 PM Keynote Talk Abstract Coming GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

  • Interplay between G protein-coupled receptors and nanotechnology

    nano-GPCRs) may enhance GPCR-related signalling and functions. of biomaterials with GPCRs in therapeutical application." soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in

  • The path of GPR87: from a P2Y-like receptor to its role in cancer progression

    < GPCR News < GPCRs in Oncology and Immunology The path of GPR87: from a P2Y-like receptor to its role oncogenic role of GPR87 in various human malignancies, presenting it as a potential novel target site for therapeutic GPCR News GPCR Jobs Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Biochemical pharmacology of adenylyl cyclases in cancer

    < GPCR News < GPCRs in Oncology and Immunology Biochemical pharmacology of adenylyl cyclases in cancer of different components in AC-related signaling could potentially lead to the development of novel therapeutic Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology

  • Coffee Break with pastries announcement of the aGEM award | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem

    Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program

  • GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression

    < GPCR News < GPCRs in Oncology and Immunology GPR176 promotes fibroblast-to-myofibroblast transition Developing a GPR176 inverse agonist or allosteric modulator is a promising therapeutic approach for fibrosis for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs , and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs into GPCR function GPCR Activation and Signaling More from Dr.

  • Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis

    < GPCR News < GPCRs in Oncology and Immunology Enterococcus-derived tyramine hijacks α2A-adrenergic receptor regulation of ISCs and colitis exacerbation and yielding a targeted therapeutic approach to restore News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs

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