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282 items found for "IJzerman AP"

  • 📰 GPCR Weekly News, September 11 to 17, 2023

    and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April

  • 📰 GPCR Weekly News, September 4 to 10, 2023

    November 2 - 4: The GPCR Retreat is approaching and we are thrilled to be sponsors! forces to revolutionize transmembrane proteins characterization in drug discovery Confo Therapeutics Appoints and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April

  • 📰 GPCR Weekly News, August 28 to September 3, 2023

    Team as the Company Advances its Multi-Product Pipeline Toward Clinical Studies Confo Therapeutics Appoints and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April

  • 📰 GPCR Weekly News, August 21 to 27, 2023

    November 2 - 4: The GPCR Retreat is approaching, and we're proud sponsors! Molecular Gating Seminar NEW March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference NEW April

  • 📰 GPCR Weekly News, August 14 to 20, 2023

    receptor is dynamic Ligand recognition and G protein coupling of the human itch receptor MRGPRX1 Improved approaches Molecular Insights into GPCR Function A method for structure determination of GPCRs in various states Apelin

  • 📰 GPCR Weekly News, August 7 to 13, 2023

    based on RNA-seq Reviews, GPCRs, and more Tri-part NanoLuc as a new split technology with potential applications

  • 📰 GPCR Weekly News, July 24 to July 30, 2023

    GPCRs in Cardiology, Endocrinology, and Taste Insights on discovery, efficacy, safety and clinical applications

  • 📰 GPCR Weekly News, July 17 to July 23, 2023

    GPCRome-wide analysis of G-protein-coupling diversity using a computational biology approach. Sosei Heptares Acquires Idorsia’s Pharmaceuticals Business in Japan and APAC (ex-China), Accelerating

  • 📰 GPCR Weekly News, July 10 to 16, 2023

    Reviews, GPCRs, and more Optical approaches for investigating neuromodulation and G Protein-Coupled Receptor Sosei Heptares Webinar Presentation for Q2 FY2023 Financial Results Neurocrine Biosciences Announces Appointment Grants Under Nasdaq Listing Rule 5635(c)(4) Confo Therapeutics CEO, Cedric Ververken, will join WuXi AppTec's

  • 📰 GPCR Weekly News, July 3 to 9, 2023

    GPCR Symposium on Structural and Molecular Insights on GPCR Activation is quickly approaching!

  • 📰 GPCR Weekly News, June 26 to July 2, 2023

    GPCR Symposium on Structural and Molecular Insights on GPCR Activation is fast approaching!

  • 📰 GPCR Weekly News, June 19 to 25, 2023

    As we approach the event, we have some news to share: We’ve decided to make this event a trainee day Drugs, and more Molecular Characterization of Two Wamide Neuropeptide Signaling Systems in Mollusk Aplysia

  • 📰 GPCR Weekly News, June 12 to 18, 2023

    Neuroscience Orphan receptor GPR88 as a potential therapeutic target for CNS disorders - an in silico approach

  • 📰 GPCR Weekly News, May 29 to June 4, 2023

    CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation. NMR applications to GPCR recognition by peptide ligands. Application of computational methods for class A GPCR Ligand discovery.

  • 📰 GPCR Weekly News, May 22 to 28, 2023

    Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation

    activation, then regulate trigger receptor internalization via interaction with the adaptor protein 2 (AP2 Based on an ingenious combination of multicolor single-molecule microscopy approach with molecular dynamics diffusing on the plasma membrane leads to their recruitment and accumulation in CCPs via interaction with AP2

  • 📰 GPCR Weekly News, May 15 to 21, 2023

    Methods & Updates in GPCR Research Computational design of dynamic receptor-peptide signaling complexes applied Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, May 8 to 14, 2023

    The application of artificial intelligence to accelerate GPCR drug discovery. Industry News InterAx Biotech to Apply its Leading AI and Cell Signalling Technology to Support Target Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • Artificial intelligence – faster, smarter, cheaper GPCR drug discovery

    High-throughput approaches used in drug discovery create large datasets regarding ligand synthesis and , ligand binding assays, signaling assays, cell imaging, protein structure determination, and omics applications the form of assumptions or hypotheses places similarity-based scoring functions at the core of any AI approach , 2021) ); 3) the same limitation holds when searching for novel receptor ligands, as “ligand-based approaches Greater application of unsupervised machine learning: most applications of ML in GPCR drug discovery

  • 📰 GPCR Weekly News, May 1 to 7, 2023

    Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • VAMP2: a crucial player in the delivery of MOR to the synapse

    general overview, after GPCRs synthesis in the endoplasmic reticulum, GPCRs are transported to the Golgi apparatus

  • 📰 GPCR Weekly News, March 20 to 26, 2023

    Methods & Updates in GPCR Research The application of targeted protein degradation technologies to G (April 20 - 21, 2023) Swiss Biotech Day (April 24 - 25, 2023) SLAS Europe 2023 Conference and Exhibition Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, March 13 to 19, 2023

    (April 20 - 21, 2023) NEW Swiss Biotech Day (April 24 - 25, 2023) SLAS Europe 2023 Conference and Exhibition Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, March 6 to 12, 2023

    the Trophée de l'Innovation Technologique (Technological Innovation Award) Sosei Heptares Receives Approval (April 20 - 21, 2023) SLAS Europe 2023 Conference and Exhibition. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential. PhD Studentship - Integrated Approaches In Pharmacology, Computer Simulations And Machine Learning To

  • 📰 GPCR Weekly News, February 27 to March 5, 2023

    & Updates in GPCR Research Time- and cost-efficient bacterial expression and purification of potato apyrase Antiverse identifies therapeutic antibodies targeting GPCRs CEO Andrew Hopkins on Exscientias AI-Driven Approach (April 20 - 21, 2023) SLAS Europe 2023 Conference and Exhibition. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential. PhD Studentship - Integrated Approaches In Pharmacology, Computer Simulations And Machine Learning To

  • 📰 GPCR Weekly News, February 20 to 26, 2023

    Application of computational methods for class A GPCR Ligand discovery. WEBINAR Using integrative biophysical approaches to understand GPCR regulation by β-arrestins. (April 20 - 21, 2023) SLAS Europe 2023 Conference and Exhibition. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential. (Protein Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry

  • 📰 GPCR Weekly News, February 13 to 19, 2023

    WEBINAR Using integrative biophysical approaches to understand GPCR regulation by β-arrestins. (April 20 - 21, 2023) SLAS Europe 2023 Conference and Exhibition. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential. Senior Scientist (Research Software Engineer) Senior Scientist – Native Mass Spectrometry Speculative Applications (Protein Biochemistry) Speculative Applications (Mass Spectrometry) Speculative Applications (Chemistry

  • Glyco-sulfo hotspots in the chemokine receptor system

    sulfation on CCR5 and CCR1 function In this study engineered cell lines, inhibitors and mutagenesis approaches Removal of the terminal sialic acid was also shown to negatively impact signaling as previously appreciated There are few examples of the applicability of the sulfo-glyco barcode in drug discovery.

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