Development and Characterization of a Highly Selective Turn-On Fluorescent Ligand for β3-Adrenergic Receptor

conformation with GFP-inspired dyes Structural basis for the ligand recognition and G protein subtype selectivity

Submit poster abstracts via this form; short talks will be selected.

Submit poster abstracts using this form; short talks will be selected from submissions.

Vesicle-associated membrane protein 2 is a cargo-selective v-SNARE for a subset of GPCRs.

Molecular Insights into GPCR Function Endogenous l- to d-amino acid residue isomerization modulates selectivity

ERK activation GPCR Binders, Drugs, and more Flipping the GPCR Switch: Structure-Based Development of Selective

GPCR signaling and utilising advanced assay technologies, researchers can identify novel drugs that selectively

If you have registered, please submit poster abstracts through this form and the short talk selections

Submit poster abstracts here; short talks will be selected from Abstracts.

GPCRs-Targeted Drug Discovery Summit, Boston MA Pathios Therapeutics Unveils PTT-4256, a Highly Potent and Selective

discovery referring to important conformational changes, allosteric properties, ligand and functional selectivity

and Signaling Constitutive activation mechanism of a class C GPCR Allosteric modulation and G-protein selectivity

Developing a novel framework for structure-based pharmacophore model generation and selection.

and biased sampling method for Huntington's disease therapy Rational design of highly stabilized and selective

alkaloid malbrancheamide reorients the lipid binding domain of GRK5 Molecular Determinant Underlying Selective

Identification of 1,3,8-triazaspiro[4.5]decane-2,4-dione Derivatives as a Novel Delta Opioid Receptor-Selective

involved in visual processing Reliability of AlphaFold2 Models in Virtual Drug Screening: A Focus on Selected

modulate biased signaling downstream of CXCR3 depending on their subcellular localization Investigating selectivity

Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity.

allosteric regulation of chemokines and antagonists using a nanoscale hCCR3 receptor sensor GPCR-G protein selectivity

The role of G protein conformation in receptor-G protein selectivity.

Nicole Perry-Hauser, on her selection as a 2024 Discovery Science Emerging Scholar at Vanderbilt University

October 3rd to 31st, 2024, to learn more about the Advanced Methods for the Optimization of Candidate Selection

degradation of membrane proteins by PROTACs and alternative targeted protein degradation techniques Ligand selectivity

signaling GPCR Binders, Drugs, and more Silicon-Rhodamine Functionalized Evocalcet Probes Potently and Selectively

Besides the differences in their structural complexity, some members of the RGS family are selective

Coordinated cellular behavior regulated by epinephrine neurotransmitters in the nerveless placozoa Selective