Search Results
146 items found for "Kallikrein-related peptidases"
- Profiling Immune Cell and Platelet Transcriptomes
gained from this research will be instrumental in shaping therapeutic strategies for a range of immune-related
- Gαs and Gαq/11 protein coupling bias of two AVPR2 mutants (R68W and V162A) that cause nephrogenic di
into the relationship between the conformational change of the receptor because of the mutation and related
- APEX2/AUR Biosensor: A Powerful Tool for Protein Interaction and Trafficking
in GPCR trafficking could profoundly affect the development of therapeutic strategies for conditions related
- G protein-coupled receptors that influence lifespan of human and animal models
mechanisms most involved in the role of GPCRs in lifespan are those that mimic dietary restriction, those related
- Crinetics Pharmaceuticals announced the formation of an independently operated new company...
development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related
- Regulator of G Protein Signaling 20 Correlates with Long Intergenic Non-Coding RNA (lincRNAs)...
cystadenocarcinoma: p = 0.048); (d) RGS20 was found to be significantly associated with some tumor-related
- GPR125 (ADGRA3) is an autocleavable adhesion GPCR that traffics with Dlg1 to the basolateral...
receptors (GPCRs) is defined by an N-terminal large extracellular region that contains various adhesion-related
- Regulators of G-protein signaling: essential players in GPCR signaling
Another signaling pathway related to RGS4 involves the regulation of the immune response. Relating to pain, RGS4 in pain regulation is a topic of increasing interest because it has been identified
- Structural dynamics of Smoothened (SMO) in ciliary membrane and its interaction with membrane lipids
to identify the interaction of membrane cholesterols with definite sites and domains within SMO and relate
- 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!
Signaling GPCRs in Neuroscience Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related
- Do You Believe AI Could Accelerate Drug Discovery?
This effort will help resolve issues related to data accuracy and bias, leading to more dependable predictions
- Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage...
applied H1152, a ROCK inhibitor, and siRNA-induced ROCK2 knockdown both depressed AMPAergic, inspiratory-related
- Embark on a GPCR Adventure: Your Weekly Research Expedition! | Oct 21-27, 2024
receptors GPCRs in Neuroscience Astrocyte Gi-GPCR signaling corrects compulsive-like grooming and anxiety-related
- Artificial intelligence – faster, smarter, cheaper GPCR drug discovery
Drug repurposing: AI algorithms can screen existing drugs and repurpose them for GPCR-related diseases By integrating this data with GPCR-related knowledge, AI can help identify patient-specific GPCR targets
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
Spurred on by new scientific and technological advances related to the understanding of structure and .0404802101 · Initial work on precision engineering of a small protein GPCR ligand using new peptide
- 📰 GPCR Weekly News, June 24 to 30, 2024
We have gathered 24 new research papers on GPCRs and updates on industry news related to GPCRs.
- Extracellular signal-regulated kinases – a potential pathway for GPCR-targeted drug discovery
unique advantages for detecting ERK activation, contributing to the broader toolkit available for GPCR-related
- 📰 GPCR Weekly News, January 1 to 7, 2024
development and diseases GPCR Activation and Signaling Proinflammatory chemokine CXCL14 activates MAS-related
- 📰 GPCR Weekly News, July 1 to 7, 2024
latest collection of 25 cutting-edge research papers on GPCRs and exciting updates on industry news related
- Structural landscape of the Chemokine Receptor system
shorter truncation variant, CCL15L, exhibits bias toward G-protein signaling, which has been structurally related However, comparing CCR6 with closely related receptors, CCR7 and CCR9, in their inactive states offers
- 📰 GPCR Weekly News, May 13 to 19, 2024
and Immunology Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related
- GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!
mechanisms and heterogeneity of astrocyte reactivity in Alzheimer's disease Identification of immune-related
- Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024
and phosphorylated receptor interaction Early Events in β2AR Dimer Dynamics Mediated by Activation-Related
- Exciting GPCR Events for Next Year! + GPCR Weekly Rocket Launch ⦿ Oct 28 - Nov 3, 2024
CXCR4 in mouse neutrophils Mechanistic exploration of bioactive constituents in Gnetum gnemon for GPCR-related
- Targeting Intracellular Allosteric Sites in GPCRs
for the administration of substantial doses of allosteric modulators with a diminished risk of target-related
- 📰 GPCR Weekly News, March 25 to March 31, 2024
Crinetics Pharmaceuticals gets grant for patent granted for somatostatin modulators for treating hormone-related
- An overview of the compartmentalized GPCR Signaling: Relevance and Implications
tagging GPCRs expressed in cellular compartments require innovative approaches to overcome barriers related
- Molecular insights into psychedelic drug action
mental health care, incremental progress in basic and clinical research, and the reconsideration and relaxation