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309 items found for "Molecular biology"

  • 📢 GPCR Update: August 19-25, 2024 | Thrilling Announcement: New Pharmacology Course Dates & Exclusive Discounts Inside!

    Mexico City Dates:  October 23-25, 2024 Connect with peers and delve into cutting-edge adhesion GPCR biology for Partnered Schizophrenia Candidate NBI-1117568 Call for GPCR Papers NEW Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Webinars September 5 - 6, 2024 assays in drug discovery NEW September 30 - October 3, 2024 | 22nd Discovery on Target October 2024 | Biologics

  • 📰 GPCR Weekly News, May 1 to 7, 2023

    Cholesterol Biases the Conformational Landscape of the Chemokine Receptor CCR3: A MAS SSNMR-Filtered Molecular Structural and Molecular Insights into GPCR Function Structural insight into an anti-BRIL Fab as a G-protein-coupled Molecular architecture of the Gαi-bound TRPC5 ion channel. (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, September 11 to 17, 2023

    Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster Structural and Molecular 2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10 Technician Senior Research Associate, In Vitro Pharmacology - Crinetics Pharmaceuticals Postdoc In Cell Biology Of Protein Trafficking Postdoctoral Fellow Researcher / Senior Researcher in Structural Biology Research

  • 📰 GPCR Weekly News, February 13 to 19, 2023

    Octopamine and tyramine signalling in Aedes aegypti: Molecular characterization and insight into potential Structural and Molecular Insights into GPCR Function Quantitative analysis of sterol-modulated monomer-dimer SLAS 2023 B Building Biology in 3D Symposium. (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, April 8 to 14, 2024

    Marina Casiraghi, Robert J Lefkowitz, Peter Gmeiner, Brian K Kobilka et al. for their investigation on Molecular GPCR Symposia Join us on June 7th for our next symposium on Structural and Molecular Insights into GPCR structures, mechanisms, and drug discovery Frizzleds act as dynamic pharmacological entities Structural and Molecular Insights into GPCR Function Molecular insights into G protein coupling specificity at a class A GPCR Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 October 2024 | Biologics

  • 📰 GPCR Weekly News, April 10 to 16, 2023

    GPCR Binders, Drugs, and more Discovery of SYD5115, a novel orally active small molecule TSH-R antagonist Structural and Molecular Insights into GPCR Function Function and dynamics of the intrinsically disordered Events, Meetings, and Webinars NEW FREE 7th ERNEST GPCR zoominar (April 20, 2023) SLAS 2023 Building Biology (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, August 7 to 13, 2023

    convergent therapeutic potential of GPCRs in autism spectrum disorders GPCRs in Oncology and Immunology Molecular GPCRs, and more Tri-part NanoLuc as a new split technology with potential applications in chemical biology : a mini-review YAP/TAZ: Molecular pathway and disease therapy Primary cilia in skeletal development NEW Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular

  • 📰 GPCR Weekly News, March 6 to 12, 2023

    Structural and Molecular Insights into GPCR Function Endogenous l- to d-amino acid residue isomerization Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. SLAS 2023 Building Biology in 3D Symposium. (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024

    City Dates:  October 23-25, 2024 Join us  to connect with peers and explore cutting-edge adhesion GPCR biology Sexton , Denise Wootten , et al., for their work on Isoquinoline small molecule ligands are agonists Photo-BQCA: Positive Allosteric Modulators Enabling Optical Control of the M1 Receptor Isoquinoline small molecule protein activation by spectrally resolved imaging fluorescence fluctuation spectroscopy Structural and Molecular September 18, 2024 | FREE Webinar - The value of GPCR cell-based assays in drug discovery October 2024 | Biologics

  • On-cell nuclear magnetic resonance spectroscopy to probe cell surface interactions

    ) spectroscopy allows the determination of atomic-level information on intermolecular interactions, molecular structure, and molecular dynamics in the cellular environment. This may be broadly divided into studies focused on obtaining detailed molecular information in the intracellular context ("in-cell") or those focused on characterizing molecules or events at the cell surface ("on-cell provide a brief survey of the applicability of on-cell NMR approaches to other classes of cell surface molecules

  • 📰 GPCR Weekly News, February 27 to March 5, 2023

    FSHR activation through small molecule modulators: Mechanistic insights from MD simulations. Structural and Molecular Insights into GPCR Function The activation mechanism and antibody binding mode SLAS 2023 Building Biology in 3D Symposium. (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface

    Intermolecular Interactions in G Protein-Coupled Receptor Allosteric Sites at the Membrane Interface from Molecular interactions and stability, the binding site structure, and how all of these are affected by lipid molecules interactions in the allosteric sites of the PAR2, C5aR1, and GCGR receptors in three lipid compositions using molecular The availability of polar atoms for interactions in such cavities can be assessed by water molecules

  • Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to...

    Our model not only shows the function of dimeric β2-AR but also provides a molecular insight into the

  • 🤯Mind-blowing GPCR Scoops! Discover the Latest Breakthroughs! ⦿ Nov 18 - 24, 2024

    Georgios Skiniotis as Director of the New Center of Excellence for Structural Cell Biology Monash Scholars July 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology GPCR Jobs NEW Scientist - Biology Scientist I Cell Biology - Tectonic Therapeutic Senior Principal Scientist, Medicinal Chemistry PhD mechanosensing Senior Scientist, GPCR Pharmacology Research Associate - Professor Graeme Milligan Postdoc in Molecular Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist

  • 📰 GPCR Weekly News

    GPCR Activation and Signaling Molecular Mechanisms of PTH/PTHrP class B GPCR Signaling and Pharmacological Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, June 3 to June 9, 2024

    This significant event in adhesion GPCR Biology will be held in vibrant Mexico City from October 23 to exciting event, which brings together scientists worldwide to explore all aspects of adhesion GPCR biology adenosine receptor signaling and regulation Novel medications for problematic alcohol use Structural and Molecular Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 October 2024 | Biologics Senior Research Associate/Associate Scientist, Protein Science Post-Doctoral Fellow—Pharmacology/Cell Biology

  • 📰 GPCR Weekly News, January 22 to 28, 2024

    cyclic nucleotide phosphodiesterases in aortic aneurysm and dissection GPCRs in Oncology and Immunology Molecular Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design Structural and Molecular Discovery March 13 - 15 | 9th German Pharm-Tox Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 1 - 4, Clinical Pharmacology 2026 GPCR Jobs Post-Doc position Lead Researcher Senior Researcher in Structural Biology

  • 📰 GPCR Weekly News, October 9 to 15, 2023

    2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10 vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist /Molecular Pharmacologist Senior Vice President, Oncology Clinical Research Scientist (level I or II)

  • 📰 GPCR Weekly News, April 24 to 30, 2023

    Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with small molecules Small-molecule targeting of GPCR-independent noncanonical G-protein signaling in cancer. Structural and Molecular Insights into GPCR Function Cryo-EM structure of the endothelin-1-ETB-Gi complex (June 4 - 8, 2023). 2023 Molecular Pharmacology (GRS) Seminar GRC. (June 10 - 11, 2023). Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • 📰 GPCR Weekly News, June 19 to 25, 2023

    GPCR Symposium on Structural and Molecular Insights on GPCR Activation. Serotonin 5-HT7 receptor slows down the Gs protein: a single molecule perspective. GPCR Binders, Drugs, and more Molecular Characterization of Two Wamide Neuropeptide Signaling Systems Discovery and in vitro Characterization of BAY 2686013, an Allosteric Small Molecule Antagonist of the Structural and Molecular Insights into GPCR Function Structure-Activity Relationship Study of the High-Affinity

  • Unlocking the Future of Medicine: Advancements in GPCR Research

    Principles of Pharmacology in Drug Discovery I - Techniques for Effective Lead Optimization of Candidate Molecules scientists and researchers and gain valuable insights into the latest developments in adhesion GPCR biology approach for combating multi-drug resistant Staphylococcus aureus Isolation, Structure Elucidation, and Biological Structural and Molecular Insights into GPCR Function Entropy drives the ligand recognition in G-protein-coupled September 18, 2024 | FREE Webinar - The value of GPCR cell-based assays in drug discovery October 2024 | Biologics

  • 📰 GPCR Weekly News, August 14 to 20, 2023

    by targeting adhesion G protein-coupled receptor F1 ( Adgrf1) GPCR Activation and Signaling Single-molecule ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens Understanding the Molecular manipulation of Gq- and Gi/o-coupled receptor signaling in neurons and heart muscle cells Structural and Molecular structure determination of GPCRs in various states Apelin receptor dimerization and oligomerization Molecular Associate Postdoc Research Associate Director, Regulatory Affairs Research Scientist/Senior Scientist I - Molecular

  • 📰 GPCR Weekly News, November 13 to 19, 2023

    Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biology β-arrestin1 is an E3 Application (ANDA) Litigation PostEra Announces a Research Collaboration with Amgen to Discover Small Molecule - 7, 2024 | 3rd GPCRs - Targeted Drug Discovery Summit March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 1 - 4,

  • 📰 GPCR Weekly News, April 1 to 7, 2024

    GPCR Symposia Join us on June 7th for our next symposium on Structural and Molecular Insights into GPCR to Nxera Domain Therapeutics to participate at premier investor and healthcare conferences Montana Molecular Phosphorylation and G-Protein Mediated Signaling Networks June 25 - 29, 2024 | FENS Forum 2024 October 2024 | Biologics physiology, optical imaging, substance use disorder, pharmacology Research Fellow Postdoctoral Fellow – Molecular

  • 📰 GPCR Weekly News, July 31 to August 6, 2023

    mechanism of the Delta opioid receptor by an agonist ADL5859 started from inactive conformation using molecular transmission Nanowire Biosensors with Olfactory Proteins: Towards a genuine electronic nose with single molecule Bispecific Monoclonal Antibodies in Multiple Myeloma: Data from ASH 2022: A Podcast Structural and Molecular Quarter and First Half of 2023 Septerna: $150 Million Raised To Discover And Advance Novel Oral Small Molecule - 29, 2024) GPCR Jobs NEW Director, Regulatory Affairs NEW Research Scientist/Senior Scientist I - Molecular

  • 📰 GPCR Weekly News, October 30 to November 4, 2023

    ligand from the tick Ixodes scapularis Evidence that pyrophosphate acts as an extracellular signalling molecule Structural and Molecular Insights into GPCR Function Hydrophobic interaction between the TM1 and H8 Function - Consequences of subcellular cAMP signaling revealed AI Predicts How GPCRs Respond to Drug-Like Molecules 2024 | SLAS2024 International Conference and Exhibition March 23 - 24, 2024 | Ligand Recognition and Molecular Gating Seminar March 24 - 29, 2024 | Ligand Recognition and Molecular Gating Conference April 5 - 10

  • 📰 GPCR Weekly News

    Structural and Molecular Insights into GPCR Function Global insights into the fine tuning of human A2AAR GPCR drug for interstitial cystitis/bladder pain syndrome: in silico protein structure analysis and molecular Deadline February 12, 2023 Current Technologies To Understand G-Protein-Coupled Receptor Molecular Pharmacology June 4-8,2023. 2023 Molecular Pharmacology (GRS) Seminar GRC. June 10 - 11. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.

  • VAMP2: a crucial player in the delivery of MOR to the synapse

    Several molecules from the SNARE complex, including vesicle-associated membrane protein 2 (VAMP2), regulate the context of GPCR recycling, this process is complex and highly regulated that involves multiple molecular This study supports the idea that proteins from the fusion machinery are specific about the cargo molecules element in its recycling), which can interact with different fusion proteins and also this different molecular You can consult the article at the following link: https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function

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