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His expertise is in molecular pharmacology and his research program focuses on the molecular and cellular

Proost , Mette M Rosenkilde Tags GPCR , allosteric modulation , chemokine , chemokine truncation , pharmacology

As a young researcher fascinated by chemokine receptors, molecular pharmacology, drug discovery, and

Caron is also past Associate Editor at JCI and served as the inaugural Associate Editor at ACS-Pharmacology

Between 2009 and 2017, he was a Group Leader at the Institute of Pharmacology and Toxicology and Rudolf

Subsequent work has focused on understanding the molecular basis of GPCR pharmacology through structure

expression of atypical receptors and non-GPCR binding partners that cumulatively influence discrete pharmacological

signaling , fibroblast behavior , fibrotic diseases , functional heterogeneity , pathophysiology , pharmacological

They emphasized the significance of mathematical models in systems biology and pharmacology and the challenges Mathematical Models in Systems Biology and Pharmacology Aurelien Rizk and Yamina discussed the importance and relevance of mathematical models in systems biology and pharmacology.

heterotrimeric G-proteins can also be activated via GPCR-independent mechanisms that remain untapped as pharmacological

Notably, genetic or pharmacological activation of GPR132 triggered the differentiation of human primary

Chemistry at the California Institute of Technology in 1985, and M.Ph . and Ph.D. in Biomedical Sciences (Pharmacology

Chemistry at the California Institute of Technology in 1985, and M.Ph . and Ph.D. in Biomedical Sciences (Pharmacology

including the CNRS silver medal, the FRM "Young Researcher" prize, the ISI “Highly Cited” and F-1000 in Pharmacology

In particular, D2R is the main pharmacological target of antipsychotic drugs prescribed for schizophrenia

Chemistry at the California Institute of Technology in 1985, and M.Ph . and Ph.D. in Biomedical Sciences (Pharmacology

., is a Professor of Pharmacology and Chemical Biology in the Emory University School of Medicine.

Chemistry at the California Institute of Technology in 1985, and M.Ph . and Ph.D. in Biomedical Sciences (Pharmacology

Using genetic modification and pharmacological strategies we demonstrate mechanistically that this ATP-driven

Caron is also past Associate Editor at JCI and served as the inaugural Associate Editor at ACS-Pharmacology

the arrestin mediated GPCR functions (Nature communications, 2015, 2021, 2022; PNAS 2021, Molecular Pharmacology

to be enhanced by GBP, indicating that both cytokines are organized within a hierarchical regulatory network presence of GBP1, indicating that GBP2 is an upstream expressional regulator of a GBP1/GBP2 cytokine network GBP2 control immune responses as well as their own expression levels through a hierarchical cytokine network

Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Columbia University Vagelos College Tall Department of Pharmacology, University of Michigan "" About Frank Kwarcinski "I am research faculty within the department of Pharmacology at the University of Michigan.

He was the director of the French network of GPCRs (GDR-3545), currently directs the International Research Network (IRN) i-GPCRnet of the CNRS, is chair of IUPHAR « Melatonin receptor » sub-committee, Editor-in-Chief

To investigate the role of conformational dynamics in the distinct pharmacological behaviors of CXCR4

In particular, D2R is the main pharmacological target of antipsychotic drugs prescribed for schizophrenia

Pharmacological inhibition of the lipid synthesis pathway by statins is a therapeutic approach to control

Javitch1,2 1Departments of Psychiatry and Molecular Pharmacology and Therapeutics, Columbia University initially became interested in GPCR signal transduction during my graduate training in the Department of Pharmacology