Small-molecule targeting of GPCR-independent non-canonical G protein signaling inhibits cancer progression

Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration

receptor (RXFP3) activation in the rat retrosplenial cortex Unveiling the therapeutic prospects of EGFR inhibition

incidence of imperforate vagina in ADGRA3-deficient mice GPCR Activation and Signaling Local anesthetics inhibit

., agonists or partial agonists), inhibition of activation (e.g., antagonists), or produce an inversion

are localized in both pre- and postsynaptic compartments and their activation is generally related to inhibiting

GPCRs in Cardiology, Endocrinology, and Taste Metabolic depletion of sphingolipids inhibits agonist-induced

Allosteric antagonists are compounds that inhibit GPCR activity by binding to intracellular allosteric

Labeling of CC Chemokine Receptor 2 with a Versatile Intracellular Allosteric Probe Selective optogenetic inhibition

In non-small-cell lung cancer OR2J3 activation induced apoptosis and inhibited cell proliferation and

PMID: 38564333 CD97 expression is upregulated upon orthodontic compression and inhibits osteoclast differentiation

Paremeters such as ligand affinity for the receptor (pKi), the ability of a ligand to induce or inhibit

Originally recognized for inhibiting G protein signaling, they also influence specific pathways such