Search Results
185 items found for "Shunda Du"
- Ep 23 with Dr. Qing Fan
Join us and learn more about Qing's work and how we powered through a technical issue during the interview
- Ep 114 with Dr. Robert F. Bruns
During a joint postdoc with John W Daly at NIH and Solomon Snyder at Johns Hopkins, he developed the
- Ep 134 with Dr. Neil Grimsey
Neil Grimsey " During my postdoctoral studies at USCD, I discovered a novel GPCR-dependent atypical kinase
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
Cancer Cells: Implications for Targeted Therapy Published date November 1, 2022 Abstract Pancreatic ductal PDAC) remains an aggressive disease that is expected to become the second cause of cancer fatalities during
- Ep 132 with Dr. Richard Premont
Whitney Foundation fellowship to support his post-doctoral work with Robert Lefkowitz and Marc Caron at Duke In 1999, obtained an independent faculty position at Duke in Gastroenterology, where he remained until heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
Abstract "Ovarian cancer ranks as a leading cause of mortality among gynecological malignancies, primarily due
- Ep 139 with Dr Silvia Sposini
I moved to London as a short experience (3 months) during my MSc but I ended up staying for a full year During my time in London I investigated regulatory mechanisms of GPCR action, namely dimerization and
- G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression
Abstract "G protein-coupled receptors (GPCRs) are essential contributors to tumor growth and metastasis due
- The β2-adrenergic receptor associates with CXCR4 multimers in human cancer cells
This lack of consensus is largely due to the inherent challenges of demonstrating the presence of multimeric
- Coronavirus Porcine Epidemic Diarrhea Virus Utilizes Chemokine Interleukin-8 to Facilitate Viral Replication by Regulating Ca2+ Flux
Chemokine production by epithelial cells is crucial for neutrophil recruitment to sites of inflammation during To our knowledge, this study is the first to uncover the function of chemokine IL-8 during coronavirus
- Signaling by Neutrophil G Protein-Coupled Receptors that Regulate the Release of Superoxide Anions
Danger-signaling molecular patterns such as the N-formylated peptides that are formed during bacterial
- Ep 113 with Dr. Prasenjit Saha
During my post-doctoral research, I was part of a study that identified the receptors of a novel human
- Ep 130 with Dr. Richard Premont
Whitney Foundation fellowship to support his post-doctoral work with Robert Lefkowitz and Marc Caron at Duke In 1999, obtained an independent faculty position at Duke in Gastroenterology, where he remained until heterotrimeric G protein, small GTP-binding protein and protein kinase pathways by GIT/PIX scaffolding complexes during
- Ep 109 with Dr. Katarina Nemec
During my PhD studies in Martin Lohse lab at the Max Delbrueck Center in Berlin, I consolidated my knowledge
- Ep 153 with Dr Jacek Mokrosiński
with Piketa and how he found a job in Seda's lab at Cambridge, where he could immediately contribute due
- Ep 100 with Dr Caron Tribute Part 1
Caron and his family moved to Durham, NC in 1977, following receipt of his BSc in Chemistry from Laval He joined the faculty of Laval University School of Medicine in 1975 and then returned to join Duke’s Duke Professor until his death.
- Ep 01 with Dr. Paul Insel
During dinner with colleagues and Alfred Gillman , co-recipient of the 1994 Nobel Prize in Physiology
- A disturbed metabolite-GPCR axis is associated with microbial dysbiosis in IBD patients: Potential role of GPR109A in macrophages
Authors Cristina Bauset, Miguel Carda-Diéguez, Andrea Cejudo-Garcés, Elena Buetas, Marta Seco-Cervera, Dulce
- Ep 19 with Dr. Fiona Marshall
after attending a lecture on how the beta-adrenergic receptor in the heart is activated by adrenaline, during
- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
The lung cancer cell line H1299-BRS3 was treated with MK-5046, an agonist of BRS3, for different durations
- Interplay between G protein-coupled receptors and nanotechnology
In turn, due to overexpression of GPCRs on the surface of various types of cells, GPCR ligands can endow
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
Such a dual role of CCR7 as a GPCR that both senses and consumes its ligand can thus provide a novel
- Ep 142 with Dr Claudia Stäubert
biochemistry from Leipzig University (Germany) being already fascinated by G protein-coupled receptors (GPCRs) due During my Ph.D. at the International Max Planck Research School “The Leipzig School of Human Origins” interest in attending a meeting about GPCRs and metabolism in the UK, but was unsure if she could make it due
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
most frequently diagnosed primary brain tumors, and are associated with multiple molecular aberrations during
- Ep 53 with Dr. Timo De Groof
During his master's studies, he specialized in Biomedical Biotechnology and Structural Biology/Biochemistry During his last year of studies, Timo performed research in the biopharmaceutical company Argen X and During his Ph.D., Timo, together with Dr. During his Ph.D., he used these nanobodies as research tools, to investigate different GPCR conformations
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
However, many cancers do not respond to ICB, prompting the search for additional strategies to achieve durable
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
Zhan, Dandan Guo, Haizhen Lin, Muhammad Asad Farooq, Chenxu Jin, Li Zhang, Ying Zhou, Jie Yao, Yixin Duan
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships presentation, I will walk you through my various career experiences and include the skills I learned during