To our knowledge, this is the first report of a CNV in the ADGRL3 gene and its first association with

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Our approach, described in detail here, uses adeno-associated viruses infused intracerebrally in order

Advances in genomic technologies, such as genome-wide association studies and next-generation sequencing , have enabled the uncovering of associations between GPCR genetic variants and diseases.

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conference will be held in Perth next year, in collaboration with the Australasian Pharmaceutical Science Association

physiological consequence of CB2 receptor activation could correct circuit-based deficits commonly associated

This article has an associated First Person interview with the first author of the paper."

receptor is a transmembrane non-GPCR protein expressed mainly in the endoplasmic reticulum membrane associated

Fzd-Dvl binding was enhanced by increased concentration of the lipid PI(4,5)P2, which is generated by Dvl-associated

Overall, these results demonstrate that stimulus salience encoding is critically associated with NPS

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Several molecules from the SNARE complex, including vesicle-associated membrane protein 2 (VAMP2), regulate link: https://www.ecosystem.drgpcr.com/structural-and-molecular-insights-into-gpcr-function/vesicle-associated-membrane-protein

proteinuria, with a worldwide incidence of 3–8% and high maternal mortality, is a risk factor highly associated

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focus lies on the mechanism behind the techniques, and the specific advantages and challenges that are associated

demonstrate with the application of ML methods that it is possible to identify the key interactions associated

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are highly conserved Adhesion GPCRs playing essential roles in the mammalian nervous system and are associated

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KEGG pathway analysis highlighted the most significant pathways associated with depression treatment,

Conformational changes that facilitate scrambling are distinct from those associated with GPCR signaling

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that Fgr interacts with arrestin-3 at multiple sites and is consistent with the locations of disease-associated

Recent evidence indicates that GPR15 may be associated with modulation of the chronic inflammatory response

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