Search Results
150 items found for "Y H Hu"
- GPR37 expression as a prognostic marker in gliomas: a bioinformatics-based analysis
, Zhichao Xu , Jingbai Zhang , Xiaorui Liu , Xiao Pang , Yunxiang Ji , Degui Liao , Miaoling Lai , Huaidong
- Pancreatic ductal adenocarcinoma, β-blockers and antihistamines: A clinical trial is needed
Numerous studies including molecular and mechanistic studies, cancer biology studies and retrospective human
- Interrogating Multiscale Receptors Functions in Space
genetic risk factors implicated in schizophrenia by large whole-genome association studies (GWAS) in humans
- Role and recent progress of P2Y12 receptor in cancer development
Authors Yanni Xi, Zhenya Min, Mianxue Liu, Xueqin Li, Zhao-Hua Yuan Tags P2Y12R , P2Y12R inhibitors ,
- Glucose and HODEs regulate Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway
Authors Jing Gao, Huiqing Liu, Yuxin Jin, Yunbo Luo, Kunlun Huang, Zhihong Liang Tags Cell communication
- GPR176 promotes fibroblast-to-myofibroblast transition in organ fibrosis progression
muscle actin (αSMA), the profibrotic factor transforming growth factor β1 (TGFβ1), and collagen in a human
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
Scordo, Gunjan L Shah, Hani Hassoun, Kylee Maclachlan, Neha Korde, Urvi A Shah, Carlyn Rose Tan, Malin Hultcrantz
- Identification of S1PR4 as an immune modulator for favorable prognosis in HNSCC through machine learning
Authors Chenshen Huang , Fengshuo Zhu , Hao Zhang , Ning Wang , Qi Huang Tags Cancer , Machine learning
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
His research team has pioneered the study of G proteins and G protein coupled receptors (GPCRs) in human
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
GPCRs regulate many functions in the human body and have earned the title of "most targeted receptors
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
Communications (12 (1):4540, 2021) with the title "Gαq controls autophagy via modulation of the mTORC1 signaling hub
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
"Establishing a nonproductive, quiescent infection within monocytes is essential for the spread of human
- Single cell G-protein coupled receptor profiling of Transcription factor 21 expressing activated kidney fibroblasts
Correlative histology was performed in human kidney tissue. TCF21, ADGRA2, S1PR3 and ADORA2A/2B were each detectable in α-SMA+ interstitial cells in human kidneys
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Results: We observed that CXCR4 forms heteromers with LPA1 in recombinant HEK293A cells and the human Authors Jong Min Hong , Jin-Woo Lee , Dong-Seung Seen , Jae-Yeon Jeong , Won-Ki Huh Tags Cancer , Chemokine
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
Authors Purbasha Bhattacharya , Umesh Kumar Dhawan , Mohammed Tayab Hussain , Praveen Singh , Karran
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
Authors Buze Chen , Xiaoyuan Lu , Qingmei Zhou , Qing Chen , Siyan Zhu , Guilin Li , Hui Liu Source Contribute
- Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
Sabrina Simoncelli , Peter J McCormick , Richard Philip Grose Tags cancer biology , cell biology , human
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
Notably, GPR132 activation by 8GL promoted differentiation and reduced colony formation in human AML Notably, genetic or pharmacological activation of GPR132 triggered the differentiation of human primary Authors Chunyang Yi, Jiacheng He, Dan Huang, Yumiao Zhao, Chan Zhang, Xiyun Ye, Ying Huang, Ruth Nussinov
- Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
Authors Chulo Park , Jin-Woo Lee , Kiheon Kim , Dong-Seung Seen , Jae-Yeon Jeong , Won-Ki Huh Source
- Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Methods: GPR81 was stably knocked down (KD) in MCF-7 human breast cancer cells which were subjected to Results: GPR81 was upregulated in multiple human cancer types and further upregulated by extracellular
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
My main topics were protein biochemistry, Drosophila husbandry, and genetics.
- Terms and Conditions | Dr. GPCR Ecosystem
liable, the company’s liability to Customer or to any third party is limited to a maximum of $100 (“One Hundred
- Session VI | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
profile, we have developed antibody-drug conjugates (ADCs) targeting CD97, by screening a synthetic human We initially tested the ADC using in vitro WST-8 viability assays in human GBM cell lines and cell types We also found significantly lower LD50 values when treating human GBM cells with the ADC (0.6788 nM), studies oncogenesis in glioblastoma, the most common brain malignancy, and chromatin organization in human
- Olfactory Receptors and Tumorigenesis: Implications for Diagnosis and Targeted Therapy
various non-olfactory tissues, serving significant physiological and pathological functions in the human the specific molecular actions and signaling pathways of olfactory receptors in the development of human
- Dynamic Phosphoproteomics of BRS3 Activation Reveals the Hippo Signaling Pathway for Cell Migration
Authors Miao Guo , Yan Zhang , Lehao Wu , Ye Sheng , Jiaqi Zhao , Zeyuan Wang , Huiyu Wang , Lu Zhang , Hua Xiao Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News
- Session II | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
His research interest lies in understanding the molecular basis for human tumor development and how to Stehlik et al. have reported that ADGRG6 expressed in lipopolysaccharide stimulated human umbilical vein
- Signaling by Neutrophil G Protein-Coupled Receptors that Regulate the Release of Superoxide Anions
Receptors that Regulate the Release of Superoxide Anions Published date July 26, 2024 Abstract "In human Authors Claes Dahlgren, Huamei Forsman, Martina Sundqvist, Lena Björkman, Jonas Mårtensson Tags GPCR
- Ultrasensitive dose-response for asbestos cancer risk implied by new inflammation-mutation model
., certain asbestos) fibers in humans and experimental animals are thought to involve modes of action