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132 items found for "chronic kidney disease"
- Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
Conclusions: Antagonizing the NPYRs has been implicated as a treatment for a wide variety of diseases
- Ep 47 with Dr Simone Promel Dr Ines Liebscher
there was not much known other than that they are huge and somehow play important roles in health and disease
- GPR97 depletion aggravates imiquimod-induced psoriasis pathogenesis via amplifying IL-23/IL-17 axis signal pathway
indicated that beclomethasone dipropionate (BDP), an agonist of GPR97, attenuated the psoriasis-like skin disease
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
Ram, Gauri Ganesh, Misun Kang, Sunita Ho, Edward C Hsiao Tags Wnt pathway inhibition , fibrotic bone disease
- The combination of brentuximab vedotin and chidamide synergistically suppresses the proliferation of T-cell lymphoma cells through the enhancement of apoptosis
Published date November 3, 2023 Abstract " Purpose: Peripheral T-cell lymphoma (PTCL) is an aggressive disease
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
Published date November 1, 2022 Abstract Pancreatic ductal adenocarcinoma (PDAC) remains an aggressive disease
- Deciphering a GPCR-lncRNA-miRNA Nexus: Identification of an Aberrant Therapeutic Target in Ovarian Cancer
primarily due to the lack of early diagnostic tools, effective targeted therapy, and clear understanding of disease
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
prenylation contributes to multiple disorders, including cancers and vascular and neurodegenerative diseases
- Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy
The median time to relapse after CAR T-cell therapy was 5 months, 53% had the extramedullary disease
- Ep 155 with Endocrine Metabolic GPCR Organizers
cellular mechanisms by which mutations in a chloride-proton antiporter cause the renal disorder Dent’s disease
- Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq
Patients with ERα-positive/PR-negative tumors have shorter disease-free and overall survival than patients
- Ep 154 with Dr Badr Sokrat
research focuses on investigating GPCR signaling and trafficking in the context of inflammation and chronic
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
0.55-0.92; P = 0.009), progression free interval (PFS) (HR: 1.776; 95% CI: 1.067-2.955; P = 0.001) and disease
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
"Background: Neuroinflammation is a widely studied phenomenon underlying various neurodegenerative diseases
- Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis
Genetic variants in RGS proteins are associated with many diseases, including cancers, although the impact
- Regulator of G protein signaling protein 6 alleviates acute lung injury by inhibiting inflammation and promoting cell self-renewal in mice
Published date December 8, 2023 Abstract " Background: Acute respiratory distress syndrome (ARDS) is a disease
- Session IV | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
then moved to King's College London, where my interest and passion for kinases in brain health and disease
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
which causes loss of sensory and motor function in the body below the level of injury, is a devastating disease
- Ep 153 with Dr Jacek Mokrosiński
novel human genetic variants identified in several GPCRs associated with obesity and other metabolic diseases
- Flash News / DrGPCR
➡️ buff.ly/4fgX4ZH #gpcr #drgpcr Oct 31, 2024 Do you know that dilated cardiomyopathy, a disease that
