Search Results
251 items found for "drug repurposing"
- A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice
studying what aspects of GPCR signaling are regulated in a sex-selective manner and how this can influence drug
- GPR37 promotes colorectal cancer against ferroptosis by reprogramming lipid metabolism via p38-SCD1 axis
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 89 with Dr. Patrick Sexton
of the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug
- Chemokine Cxcl1-Cxcl2 heterodimer is a potent neutrophil chemoattractant
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 84 with Rosie Dawaliby
Rosie Dawaliby "I’m an expert in early-stage drug discovery, targeting membrane proteins, especially
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 140 with Dr Alix A J Rouault
Karine Pichavant , I contributed to the development of a drug to treat hypovolemic shock after severe In-vivo techniques, I adapted my arrestin recruitment assay to a high throughput screening format for drug
- The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Chemoattractant receptor signaling in humoral immunity
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Ep 104 with Dr. Raul Gainetdinov
of the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug
- Chemokine Physiology in Cancer
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Expanding role of CXCR2 and therapeutic potential of CXCR2 antagonists in inflammatory diseases and cancers
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Aberrant hormone receptors regulate a wide spectrum of endocrine tumors
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Targeting adenosine signaling for immuno-oncology
Dr Stagg has served as an expert consultant in the development of adenosine-targeting drugs, several
- GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Stable Binding of Full-Length Chemerin is Driven by Negative Charges in the CMKLR1 N-terminus
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Intermediate-state-trapped mutants pinpoint G protein-coupled receptor conformational allostery
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma cells in vitro
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs