Search Results
173 items found for "A3 adenosine receptor"
- Ep 109 with Dr. Katarina Nemec
Ljubljana, Slovenia, and at the University of Bonn, Germany, working initially on the role of prostaglandin receptor
- Ep 89 with Dr. Patrick Sexton
, a corresponding member of the International Union of Basic and Clinical Pharmacology Committee on Receptor
- Unbiased multitissue transcriptomic analysis reveals complex neuroendocrine regulatory networks mediated by spinal cord injury-induced immunodeficiency
Zfhx2, Gpr83, and Chrm2) were enriched in pathways related to inhibitory Gi-mediated G protein-coupled receptor neuroinflammation spreads after injury, and neurotransmission through Gi-mediated G protein-coupled receptors
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
EVs express prosaposin, which binds to macrophage GPR37 to increase expression of the efferocytosis receptor
- Ep 48 with Dr Nyla Naim Dr Michael Lemieux Dr Jason Nasse from Addgene
his Ph.D. in Neuroscience from Ohio State University focusing on synaptic plasticity and adrenergic receptor
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
Here, we demonstrate that CB2, a G-protein-coupled receptor (GPCR) and member of the endocannabinoid
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
Membrane-bound receptors, such as the proton-sensitive GPCR (pH-GPCR) GPR4, are considered as potential
- Applying Pharmacology to Drug Discovery
My interests are in receptor theory, pharmacology applied to drug discovery and allosteric protein function
- Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
This established Peptidase M84 as a drug candidate for receptor mediated targeted-therapy of ovarian
- About Us | Dr. GPCR Ecosystem
GPCR Ecosystem We bring the GPCR community to fuel GPCR drug discovery one receptor at a time.
- AGPCR 24 Session VIII
Much of this work centered on elucidating novel mechanisms by which β-adrenergic receptors impact cardiac Characterization of Phenotypes Associated with GPR110 Deletion Hee-Yong Kim Abstract "G-protein coupled receptor GPR110 is also highly expressed in the kidney, however, little is known about the function of this receptor
- Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma
G-protein-coupled receptor class C group 5 member D (GPRC5D), an orphan GPCR predominantly expressed
- Unveiling Non-Canonical Functions for Gαq Signaling Pathways
Ribas has also described a new protective role of G protein-coupled receptor kinase 2 (GRK2), a known
- AGPCR 24 Leave for dinner reception
Mexico City, Mexico October 23-25 Download PDF Program HERE < Back to Full Agenda Leave for dinner reception
- Welcome Reception and Poster Session 1
GPCR Retreat Program < Back to schedule Welcome Reception and Poster Session 1 Date & Time Thursday,
- AGPCR 24 Session VI
associated Epilepsy Uwe Wolfrum Abstract "ADGRV1 is the largest member of adhesion G protein-coupled receptor localized in the developing and adult synapses and interact with synaptic scaffold proteins and glutamate receptors Several adhesion G protein-coupled receptors (aGPCRs) have recently been shown to play critical roles
- Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
Moreover, receptor-integrin interactions were required for effective downstream signalling, leading to
- NPFF stimulates human ovarian cancer cell invasion by upregulating MMP-9 via ERK1/2 signaling
NPFF regulates a variety of physiological functions by binding to a G protein-coupled receptor (GPCR)
- Regulator of G protein signaling 16 restrains apoptosis in colorectal cancer through disrupting TRAF6-TAB2-TAK1-JNK/p38 MAPK signaling
(RGS) protein family modulators play essential role within regulating downstream signaling of GPCR receptors
- Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
In the present study, we first develop a mechanistic mathematical model of a G-protein coupled receptor
- The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure
G-protein-coupled receptors (GPCRs) are the most intensively studied drug targets but are underexplored
- Exploiting frequent and specific expression of PRL3 in pediatric solid tumors for first-in-child use of PRL3-zumab humanized antibody
tumors in relation to survival outcomes, expression of angiogenesis markers, and G-protein-coupled receptor
- CircFKBP5 Suppresses Apoptosis and Inflammation and Promotes Osteogenic Differentiation
pull-down assays were used to confirm the binding between miR-708-5p and circFKBP5 or G-protein-coupled receptor
- Advanced data analysis for GPCR pharmacology
He completed his Ph.D. in biochemistry, studying allosteric modulation of dopamine receptors, from the
- Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
Previously, we identified potent positive crosstalk between insulin/IGF-1 receptors and G protein-coupled
- Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors
wild-type and mutant GNAS samples identified by nontargeted proteomics and involved in G protein-coupled receptor
- Respiratory infections predominate after day 100 following B-cell maturation antigen-directed CAR T-cell therapy
Infections are an important complication after B-cell maturation antigen (BCMA)-directed chimeric antigen receptor
- Ep 66 with Dr. Antony A. Boucard Jr
interest in the cardiovascular system by investigating the structure of the Angiotensin and Urotensin receptors