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450 items found for "G protein-coupled receptor (GPCR)"
- Ep 46 with Dr Gunnar Schulte
GPCR Podcast << Back to podcast list Dr. Gunnar Schulte About Dr. section Receptor Biology and Signaling at the Department of Physiology and Pharmacology. Molecular Neurobiology; 2003-2005) and later with Roger J Summers (Monash University, Melbourne Australia, GPCR , the relevance of receptor dynamics, and receptor complex composition for signal initiation and specification GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 154 with Dr Badr Sokrat
Among other projects, I studied the role of β-arrestin in G protein trafficking, the impact of GPCR ubiquitination early tasks at Michelle’s lab, which involved creating stable cell lines and identifying potential protein the potential of multiplexing assays in expanding the scope of scientific exploration and finding new protein Yamina shared her experiences at Rockefeller, where she studied chemical receptors. GPCR to serve as a global hub for the GPCR community.
- Ep 59 with Dr. Nicola J. Smith
GPCR Podcast << Back to podcast list Dr. Nicola J. Smith About Dr. Nicola J. Smith Dr. Smith’s team has made advances in the understanding of how an orphan GPCR exerts its effects both in developing a powerful new computational tool for identifying ‘surrogate’ ligands (borrowed from other receptors ) for orphan GPCRs, named GPCR-CoINPocket. from ‘locked’, inaccessible receptors to well-characterized and understood ‘unlocked’ therapeutic targets
- Ep 19 with Dr. Fiona Marshall
GPCR Podcast << Back to podcast list Dr. Fiona Marshall About this episode Fiona Marshall got fascinated with GPCRs after attending a lecture on how the beta-adrenergic receptor in the heart is activated by adrenaline, during her undergraduate of the GABAB receptor. As a co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
Since only migratory DCs express this chemokine receptor, it is unclear how monocytes reach the LN. Migratory monocytes expressed Ccr5, a high-affinity receptor for Ccl5. News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Newsletter for Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Register AGPCR Newsletter Dr GPCR News Adhesion GPCR Consortium Newsletter - May 2024 Welcome to the 4th official Adhesion GPCR Consortium Register for the Adhesion GPCR 2024 Learn more about the Adhesion GPCR workshop 2024 Up About the event Learn more about the Adhesion GPCR workshop 2024 and its preliminary program.
- Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to About Joshua Gross "I am a neuropharmacologist interested in exploiting GPCR biased signaling to design GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
GPR143 interacts with HRS (an ESCRT-0 Subunit) and promotes its association to cargo proteins, such as EGFR, which subsequently enables selective protein sorting into intraluminal vesicles (ILVs) in multivesicular ESCRT pathway promotes secretion of exosomes that carry unique cargo, including integrins signaling proteins Taejoon Kwon , Pann-Ghill Suh , Young Chan Chae Tags GPR143 , HRS , MVB , breast cancer , exosomal protein papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more
- Ep 31 with Dr. Kevin Pfleger
GPCR Podcast << Back to podcast list Dr. Kevin Pfleger About this episode Dr. I sat down with Kevin to chat about GPCRs, pharmacology, and his contributions to the field in both the Professor Pfleger has developed extensive expertise in profiling receptor binding and function at the molecular and cellular levels over the last 20 years, particularly involving GPCRs. Investigation Technology (Receptor-HIT) for studying heteromers.
- Ep 78 with Dr. Stuart Maudsley
GPCR Podcast << Back to podcast list Dr. Stuart Maudsley About Dr. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next
- Ep 88 with Dr. Hannes Schihada
GPCR Podcast << Back to podcast list Dr. Hannes Schihada About Dr. Hannes Schihada Following studies in Pharmacy in Regensburg, Germany, I joined the receptor pharmacology My project involved the development of FRET/BRET -based GPCR conformational biosensors, which can be I spent 2 1/2 years in his lab and developed novel conformational sensors for these intriguing receptors GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 64 with Dylan Eiger
GPCR Podcast << Back to podcast list Dylan Eiger About Dylan Eiger Dylan Eiger is currently an MD/Ph.D Dylan's graduate research focuses on the mechanisms underlying biased signaling at GPCRs, specifically , the role of differential receptor phosphorylation (phosphorylation barcodes) and subcellular GPCR signaling He primarily studies the chemokine receptor CXCR3 as it has three naturally occurring ligands and thus He hopes to continue his research on biased agonism at GPCRs with a particular focus on the treatment
- Ep 114 with Dr. Robert F. Bruns
GPCR Podcast << Back to podcast list Dr. Robert F. Bruns About Dr. Robert F. Bruns Fred Bruns discovered the first positive allosteric modulator (PAM) of a GPCR in the late 1980s He then joined WL/PD, where his lab demonstrated the existence of two subtypes of the adenosine A2 receptor In 1988, he joined Lilly as a receptor biologist in charge of a high-throughput screening lab. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs
- Ep 153 with Dr Jacek Mokrosiński
GPCR Podcast << Back to podcast list Exploring Career Paths in GPCR Research with Dr. and worked closely with Dr Birgitte Holst studying structural and mechanistic properties of ghrelin receptor and GPCRs involved in regulation of metabolism. understanding the dynamics of receptor signalling. Jacek shared his fascination with the growth hormone secretion receptor and the melanocortin 4 receptor
- Ep 43 with Dr. Stuart Maudsley
GPCR Podcast << Back to podcast list Dr. Stuart Maudsley About Dr. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 72 with Dr. Stuart Maudsley
GPCR Podcast << Back to podcast list Dr. Stuart Maudsley About Dr. Following this tremendous experience, he was recruited to be the Principal Investigator of the Receptor To broaden his biomedical skill-set Stuart next accepted the position of Head of the Receptor Pharmacology Stuart’s current research, in the Receptor Biology Lab, focuses on the development of novel GPCR-based GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 04 with Dr. Graciela Pineyro
GPCR Podcast << Back to podcast list Dr. Graciela Pineyro About this episode Dr. Graciela Pineyro’s love for GPCR pharmacology started in Uruguay where she first worked on the serotonin receptors. Graciela has done extensive work on the molecular pharmacology of opioid receptors, exploring their signaling GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 20 with Dr. Jennifer Pluznick
GPCR Podcast << Back to podcast list Dr. Jennifer Pluznick About this episode Dr. Pluznick discovered that olfactory receptors in mice are also expressed in their kidneys and blood vessels Her research is focused on the role of chemosensory GPCRs in regulating renal and cardiovascular function , and identifying renal/cardiovascular olfactory receptor ligands, and relating them to whole-animal GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 12 with Dr. Antonella Di Pizio
GPCR Podcast << Back to podcast list Dr. GPCR podcast , we meet with Dr. Antonella then moved to Israel, where she first started working on bitter taste GPCRs in Dr. Today, Antonella has expanded her research to olfactory GPCRs and trace amine receptors. GPCR Ecosystem Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next
- GPCR Retreat | Dr. GPCR Ecosystem
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat The GPCR Retreat focuses on advances in our understanding of how GPCRs operate in cell communication. The main goal of the GPCR Retreat is to provide a venue for students, post-doctoral fellows, and principal Registration to the GPCR Retreat is capped at 200 participants to promote an intimate environment. in the Ottawa 2017 edition, to showcase the breadth of diversity in GPCR trainee communities.
- Ep 54 with Dr. JoAnn Trejo
GPCR Podcast << Back to podcast list Dr. JoAnn Trejo About Dr. JoAnn Trejo Dr. GPCRs. receptors (PARs) and the impact on vascular inflammation and cancer progression. PARs are GPCRs that are activated through an atypical irreversible proteolytic mechanism. Her laboratory is the recognized expert on protease-activated receptors, particularly PAR1, and over
- Ep 22 with Dr. Kari Johnson
GPCR Podcast << Back to podcast list Dr. Kari Johnson About this episode Dr. All through her career, the recurring theme in Kari’s work has been GPCRs and more specifically Metabotropic Glutamate Receptors. Join me and learn more about how Kari studies GPCRs in basal ganglia circuits following chronic alcohol GPCR Ecosystem Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next
- Ep 128 with Dr. Ilana Kotliar
GPCR Podcast << Back to podcast list Dr. Ilana Kotliar About Dr. Ilana uses chemical biology-based methods to study the regulation and protein-protein interactions of GPCRs and a small family of accessory proteins called RAMPs. Ilana’s research is multi-disciplinary and involves a close collaboration with proteomics experts at GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs
- Ep 40 with Dr. Brian Bender
GPCR Podcast << Back to podcast list Dr. Brian Bender About Dr. Brian Bender Dr. Brain’s work there primarily focused on structure prediction of GPCRs from sparse experimental data. large compound libraries with the goal of finding new chemical matter to probe understudied and orphan receptors Brian is one of the organizers of the upcoming Transatlantic ECI GPCR Symposium . Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Ep 24 with Dr. Masha Niv
GPCR Podcast << Back to podcast list Dr. Masha Niv About this episode Dr. Her work focuses on both sweet and bitter taste receptor GPCRs and her lab established the BitterDB . GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- Cannabinoid compounds to augment L-DOPA treatment in Parkinson's Disease
Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to Michel Bouvier working on the topic of GPCR dimerization/oligomerization. the Vesicular Monoamine Transporter 2 (VMAT2), Tyrosine Hydroxylase (TH) and Trace Amine Associate Receptor GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by
- Context-dependent ciliary regulation of hedgehog pathway repression in tissue morphogenesis
We studied hedgehog pathway repression by the GPCR GPR161, and the ankyrin repeat protein ANKMY2 that direct cAMP/protein kinase-A signaling by cilia in GLI-R generation. News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
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