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467 items found for "GPCR therapeutics"
- Mexico City Nocturnal Tour, Food and drinks | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Full Agenda Adhesion GPCR workshop 2024 CINVESTAV, Mexico City, Mexico October 23-25 Download PDF Program
- Ep 86 with Nicole (Nicki) Perry-Hauser
GPCR Podcast << Back to podcast list Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral build a productive, independent scientific research career in adhesion G protein-coupled receptor (aGPCR Mutations in aGPCRs have been linked to various neuropsychiatric phenotypes, and my work will provide a basis for understanding aGPCR biology in the nervous system. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand
- A2aR on lung adenocarcinoma cells: A novel target for cancer therapy via recruiting and regulating tumor-associated macrophages
< GPCR News < GPCRs in Oncology and Immunology A2aR on lung adenocarcinoma cells: A novel target for LUAD cells drives TAMs migration and polarization, and blockade of A2aR may support a novel and potent therapeutic Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- Activation of orphan receptor GPR132 induces cell differentiation in acute myeloid leukemia
To explore the therapeutic potential of GPR132 signaling, we screened and validated a natural product News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- GPR56 signaling pathway network and its dynamics in the mesenchymal transition of glioblastoma
< GPCR News < GPCRs in Oncology and Immunology GPR56 signaling pathway network and its dynamics in the heterogeneously in glioblastoma (GBM) and is involved in the mesenchymal transition, making it a promising therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines
< GPCR News < GPCRs in Oncology and Immunology [1,2,4]Triazolo[1,5-c]pyrimidines as Tools to Investigate interesting results pave the way to further investigations on both the mechanism involved and the possible therapeutic Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience insights into GPCR function GPCR Activation and Signaling More from Dr.
- Wnt pathway inhibition with the porcupine inhibitor LGK974 decreases trabecular bone but not fibrosis in a murine model with fibrotic bone
< GPCR News < GPCRs in Oncology and Immunology Wnt pathway inhibition with the porcupine inhibitor LGK974 serve as a promising therapeutic strategy for FD. Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- Applying Pharmacology to Drug Discovery | Dr. GPCR Ecosystem
Demand 4 modules - 4 hours total Get Started Premium Members benefits: - Subscribe and save 25% on every GPCR Course - Early-bird access - Recordings will be available < Back to GPCR courses The main objective What makes each drug type unique to therapeutic pharmacology? 3.
- Gallein, G protein βγ subunits inhibitor, suppresses the TGF-α-induced migration of hepatocellular carcinoma cells via inhibition of the c-Jun N-terminal kinase
< GPCR News < GPCRs in Oncology and Immunology Gallein, G protein βγ subunits inhibitor, suppresses the Small molecules targeting the subunits of Gα and Gβγ have been developed as cancer therapeutics. News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Leukotriene B4 receptor 2 governs macrophage migration during tissue inflammation
< GPCR News < GPCRs in Oncology and Immunology Leukotriene B4 receptor 2 governs macrophage migration demonstrate that BLT2 mediates macrophage migration during inflammation, which implicates it as a potential therapeutic soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in
- Minireview: functional roles of tissue kallikrein, kinins, and kallikrein-related peptidases in lung cancer
< GPCR News < GPCRs in Oncology and Immunology Minireview: functional roles of tissue kallikrein, kinins Furthermore, their modulation could be considered as a promising approach in lung cancer therapeutics News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer
< GPCR News < GPCRs in Oncology and Immunology Agonists of galanin subtype 2 receptor may prevent pancreatic agonist enhances expression of GAL2 receptor, not only in PDAC-PDX but also in healthy tissue indicating therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- S1P Signaling Genes as Prominent Drivers of BCR-ABL1-Independent Imatinib Resistance and Six Herbal Compounds as Potential Drugs for Chronic Myeloid Leukemia
Moreover, the S1P signaling genes are promising therapeutic targets and plausible new innovation avenues News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling
< GPCR News < GPCRs in Oncology and Immunology Pharmacological inhibition of neuropeptide Y receptors Therefore, these antagonists may aid in the development of novel cancer therapeutics and patient-based Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- G protein-coupled receptors: A target for microbial metabolites and a mechanistic link to microbiome-immune-brain interactions
an improved understanding of gut microbiota-immune-brain molecular interactions and their potential therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- PAXIP1-AS1 is associated with immune infiltration and predicts poor prognosis in ovarian cancer
< GPCR News < GPCRs in Oncology and Immunology PAXIP1-AS1 is associated with immune infiltration and News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
< GPCR News < GPCRs in Oncology and Immunology Exacerbating effects of single-dose acute ethanol exposure Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >
- Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration
< GPCR News < GPCRs in Oncology and Immunology Simultaneous activation of CXC chemokine receptor 4 and interplay between CXCR4 and HRH1, and suggest the possibility of the CXCR4-HRH1 heteromer as a potential therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
< GPCR News < GPCRs in Oncology and Immunology Systems Pharmacodynamic Model of Combination Gemcitabine pancreatic adenocarcinoma (PDAC) continues to present a formidable clinical challenge, demanding innovative therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Activation of PI3K/Akt pathway by G protein-coupled receptor 37 promotes resistance to cisplatin-induced apoptosis in non-small cell lung cancer
< GPCR News < GPCRs in Oncology and Immunology Activation of PI3K/Akt pathway by G protein-coupled receptor Therefore, our findings demonstrated that GPR37 may represent a viable therapeutic target for NSCLC." News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor
< GPCR News < GPCRs in Oncology and Immunology The orphan G protein-coupled receptor 141 expressed in controlling the functions of monocytes and dendritic cells and that targeting GPR141 may be a possible therapeutic Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions
< GPCR News < GPCRs in Oncology and Immunology CaaX-motif-adjacent residues influence G protein gamma Pharmacological inhibition of the lipid synthesis pathway by statins is a therapeutic approach to control News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Flash News / DrGPCR
#gpcr #drgpcr Dec 11, 2024 Ready to stand out in the GPCR world? GPCR. subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic discovery programs that extend the discovery process and increase therapeutic opportunity. ✳️ Register world of GPCRs.
- RGS20 promotes non-small cell lung carcinoma proliferation via autophagy activation and inhibition of the PKA-Hippo signaling pathway
< GPCR News < GPCRs in Oncology and Immunology RGS20 promotes non-small cell lung carcinoma proliferation inhibition of the PKA-Hippo signaling pathway Published date March 2, 2024 Abstract " Background: Novel therapeutic News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
< GPCR News < GPCRs in Oncology and Immunology Investigating isoform switching in RHBDF2 and its role In the past, studies predicting therapeutic drug targets for cancer therapy focused on the assumption Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases
< GPCR News < GPCRs in Oncology and Immunology Neuroimmune interplay during type 2 inflammation: symptoms , mechanisms and therapeutic targets in atopic diseases Published date August 25, 2023 Abstract "Type Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology
- LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Moreover, our findings propose a therapeutic potential in combined CXCR4 and LPA1 inhibitors for cancer to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs , and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology , and Taste GPCRs in Oncology and Immunology Structural and molecular insights into GPCR function GPCR
- Ep 37 with Dr. Samuel Hoare
company supporting pharmaceutical, life science, and academic scientists in the development of new therapeutics analysis of drug action and is known for applying binding kinetics to the development of effective therapeutics , particularly GPCR antagonists. of GPCR function to better target receptors. GPCR Member ResearchGate Dr.