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576 items found for "GPCRs"

  • GPCR Weekly Whirlwind: Top Receptor Highlights from Sep 30 - Oct 6, 2024!

    Hey there, GPCR Enthusiasts! Are you geared up for your GPCR fix of the day? GPCR Event Spotlight 11th Adhesion GPCR Workshop    📍  Mexico City 📅 October 23 - 25, 2024 Hurry, there Classified GPCR News  Let’s dive into the   Classified GPCR News from September 30th to October 6th, Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and 25 - 27, 2024 | 1st Virtual GPCR Forum Conference November 26 - 28, 2024 | GPCRs-Targeted Drug Discovery

  • Dr. Juan José Fung - Dr. GPCR Podcast

    GPCR Podcast is back this week with a brand new episode. Our guest is none other than Dr. Juan Jose Fung, Principal Scientist, at GPCR Therapeutics. https://buff.ly/32fzGbO #gpcr #drgpcr #podcast

  • 🧠Do you want to share your #GPCR knowledge?

    🧠Do you want to share your #GPCR knowledge? Come to Dr. GPCR Ecosystem and create a course on your favorite #GPCR research, technique and more… Available for GPCR Ecosystem paid memberships ➡️https://bit.ly/3R8ZZbo #gpcr #drgpcr

  • Don't miss the chance to be part of the Dr. GPCR Summit 2022!

    GPCR Summit 2022 held between Oct. 10 - 16, it's FREE! Join the #GPCR movement by signing up now! ➡️ https://bit.ly/3cKMXlw #gpcr #drgpcr

  • Unlock the Future of GPCR Science: Breakthroughs and Courses Await | Sep 2 - Sep 8, 2024

    Hello GPCR Enthusiasts, Dive into this week's exciting updates on cutting-edge GPCR research, new learning GPCR Event Spotlight Discovery on Target’s 19th Annual GPCR-Based Drug Discovery Targeting G Protein-Coupled Classified GPCR News  Let’s dive into the   Classified GPCR News from September 2nd to 8th, 2024 Industry Engaging multiple sclerosis by drugging a “simple” GPCR. Papers Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings

  • 📰 GPCR Weekly News, March 27 to April 4, 2023

    GPCR Symposium on GPCR Activation and Signaling held on May 19th, 2023. Adhesion GPCRs Optimized genetic code expansion technology for time-dependent induction of adhesion GPCR-ligand GPCRs in Neuroscience Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced Reviews, GPCRs, and more NMR applications to GPCR recognition by peptide ligands. GPCR Ecosystem

  • Join Dr. GPCR Summit 2022 in 3 simple steps!

    GPCR event of the year is the 3rd edition of the Summit. Come join us from October 10 to 16 to hear about exciting #GPCR research from amazing speakers. GPCR Ecosystem site member to attend the Summit, it’s free! ➡️ https://bit.ly/3SUkB8D #gpcr #drgpcr

  • GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...

    September 2022 GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization We investigated the influence of specific inhibitors of G protein-coupled receptors (GPCR), endocytosis The inhibitors of GPCR, ERK1/2, phagocytosis, and clathrin-mediated endocytosis (CME) as well as siRNA Overall, phagocytosis, CME, GPCR, ERK signaling, and S2R/TMEM97 are involved in the internalization of Read more at the source #DrGPCR #GPCR #IndustryNews

  • Verily links up with Sosei Heptares for GPCR drug discovery

    has been on the rise in biotech in recent years as researchers have discovered the vast potential for GPCR-targeting to that star are Verily and Sosei Heptares , which have struck a research agreement to discover new GPCR details of the strategic collaboration weren’t released, but Sosei Heptares ’ past two team-ups in GPCR-based Read more at the source #DrGPCR #GPCR #IndustryNews

  • Dr. GPCR Virtual Cafe with Matthew Eddy - New date!

    GPCR Virtual Cafe session with Dr. Matthew E. on Friday, October 7th at 1 PM ET.

  • 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!

    Dear GPCR Enthusiasts! Get ready to save the dates! Dr. behaviors for innovative drug profiles GPCR Event Highlight  11th Adhesion GPCR Workshop    Location for their work on GPCR pharmacogenomics  Let’s dive into the   Classified GPCR News  from August 5th GPCRs and mRNA antigens enable drug discovery and development Mapping GPCR-RAMP complexes with MolBoolean using Spectral Shift for GPCRs October 23 - 25, 2024 | 11th Adhesion GPCR Workshop November 5 - 7, 2024

  • 📰 GPCR Weekly News, February 27 to March 5, 2023

    Hello Readers👋, GPCR weekly newsletter is here! GPCR Symposium event held on March 24th. GPCRs in Neuroscience Physiological Condition Dependent Changes in Ciliary GPCR Localization in the Brain Papers GPCRs: Signal Transduction. GPCR Ecosystem

  • Dr. Josephine (Pina) Cardarelli - Dr. GPCR Podcast

    GPCR Podcast, we have Dr. Pina Cardarelli, CSO of GPCR Therapeutics. ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr#drgpcr #podcast

  • Dr. Nicola J. Smith - Dr. GPCR Podcast

    GPCR Podcast, we have Dr. https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr #podcast

  • 📰 GPCR Weekly News, January 30 to February 5, 2023

    GPCR News, please subscribe to your monthly newsletter. Below is your Classified GPCR News at a glance for January 30th to February 5th, 2023. Papers GPCRs: Signal Transduction. Deadline extended to March 31st, 2023 GPCR Events, Meetings, and Webinars 2nd GPCR-Targeted Drug Discovery GPCR Ecosystem

  • Transmembrane domains of GPCR dimers – a novel hot spot for drug discovery

    But what are the conformation changes that drive GPCR dimerization? How dynamic are GPCRs dimer interfaces? GPCRs constantly bind to form dimers and dissociate to form monomers. But how can we target GPCR dimers? via%3Dihub #GPCR #DrGPCR#Ecosystem

  • Dr. Peter Robert Banks - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. Listen where you get your podcasts. https://www.ecosystem.drgpcr.com/dr-gpcr-podcast/ #gpcr #drgpcr #

  • Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1

    Read more at the source #DrGPCR #GPCR #IndustryNews

  • GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for...

    October 2022 GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches Read more at the source #DrGPCR #GPCR #IndustryNews

  • Mechanistic basis of GPCR activation explored by ensemble refinement of crystallographic structures

    October 2022 "G protein-coupled receptors (GPCRs) are important drug targets characterized by a canonical Recent advances in X-ray crystallography and cryo-EM have resulted in a wealth of GPCR structures that adrenergic receptor (β2 AR) and A2A adenosine receptor (A2A AR). " Read more at the source #DrGPCR #GPCR

  • Dr. Tim De Groof - Dr. GPCR Podcast

    GPCR podcast is now available! Our guest is Dr. Tim De Groof! It’s not often when you get the best of both worlds - nano-bodies and #GPCRs. Listen where you get your podcasts https://www.ecosystem.drgpcr.com/dr-gpcr-podcast #gpcr #drgpcr #podcast

  • Cholesterol occupies the lipid translocation pathway to block phospholipid scrambling by a GPCR

    September 2022 "Class A (rhodopsin-like) G protein-coupled receptors (GPCRs) are constitutive phospholipid scrambling is not detectable in the resting plasma membrane of mammalian cells that is replete with GPCRs considered whether cholesterol, a prominent component of the plasma membrane, limits the ability of GPCRs This mechanism may explain the inability of GPCRs to scramble lipids at the plasma membrane." Read more at the source #DrGPCR #GPCR #IndustryNews

  • GPCR voltage dependence controls neuronal plasticity and behavior

    G-protein coupled receptors (GPCRs) play a paramount role in diverse brain functions. Almost 20 years ago, GPCR activity was shown to be regulated by membrane potential in vitro, but whether the voltage dependence of GPCRs contributes to neuronal coding and behavioral output under physiological Here we show that muscarinic GPCR mediated neuronal potentiation in vivo is voltage dependent. crucial involvement of GPCR voltage dependence in neuronal plasticity and behavior.

  • Allosteric modulation of GPCRs: From structural insights to in silico drug discovery

    October 2022 "G protein-coupled receptors (GPCRs) play critical roles in human physiology and are one endogenous ligands (orthosteric site), allosteric modulators offer new avenues for the regulation of GPCR Recent advances in the structure determination of GPCRs bound to different types of allosteric modulators In this review, we provide a systematic analysis of the currently available GPCR structures in complex Read more at the source #DrGPCR #GPCR #IndustryNews

  • GPCRS: AN ODYSSEY FROM STRUCTURE, SIGNALING AND REGULATION TO THERAPEUTICS

    09, 2022 | | SNOWBIRD RESORT, UTAH, UNITED STATES The superfamily of G protein-coupled receptors (GPCRs mechanisms of GPCR function has revealed new paradigms with increasingly complex models of receptor Spatial-temporal signaling of GPCRs and physiological functions; 2. GPCRs as environmental sensors; 3. New approaches to GPCR drug discovery.

  • 📅 Dr. GPCR Summit 2022 is less than a month away!

    GPCR Summit 2022 is less than a month away! Come live and breathe GPCRs with us and don’t forget to submit your abstract. ➡️https://bit.ly/3Q7hlnT #gpcr #drgpcr

  • Statin-induced increase in actin polymerization modulates GPCR dynamics and compartmentalization

    regulating the dynamics of the serotonin1A receptor, a crucial neurotransmitter G protein-coupled receptor (GPCR in understanding the modulatory role of the membrane environment on the organization and dynamics of GPCRs Read more at the source #DrGPCR #GPCR #IndustryNews

  • Residency time of agonists does not affect the stability of GPCR-arrestin complexes

    September 2022 " Background and purpose: The interaction of arrestins with G-protein coupled receptors (GPCRs GPCRs that internalize without arrestin have been classified as "class A" GPCRs whereas "class B" GPCRs The interaction of arrestins with GPCRs requires both agonist activation and receptor phosphorylation Read more at the source #DrGPCR #GPCR #IndustryNews

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