GPRASP1 loss-of-function links to arteriovenous malformations by endothelial activating GPR4 signals Mechano-sensitivity

This paper thoroughly investigated the role of single amino acid changes to clarify the molecular mechanisms

extravasated to the salivary glands via a pertussis toxin-sensitive, Gi/o-dependent and CREB-independent mechanism

autophagy in health and disease GPCR Binders, Drugs, and more Elucidation of active components and target mechanism

selectivity of the G-protein lies in intrinsic features of the receptor rather than in a serotonin-induced mechanism

Structure, Mechanism, and Drug Interactions of GPCRs, Ion Channels, and Transport Proteins (March 24

The diversity in GPCR signaling regulation suggests an individualized control mechanism. Nonetheless, there is an ongoing need to delve deeper into the intricate mechanisms governing GPCR activation

in GPCR mechanosensing   GPCR Activation and Signaling Opioid receptors reveal a discrete cellular mechanism

Anionic phospholipids control mechanisms of GPCR-G protein recognition.

Annual Meeting IRN I-GPCRNet (October 25 - 27, 2023) GPCR Retreat (November 2 - 4, 2023) NEW Structure, Mechanism

Dates:  October 3 to 24, 2024 (four sessions) Topics:  Measuring pharmacologic activity, mechanisms of

is a potent neutrophil chemoattractant Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms

Certificate Explore: Key metrics for assessing ligand pharmacology (affinity, efficacy, co-operativity) Mechanisms

polycystic ovarian syndrome by modulating GPCR41/43 and PROKR1 GPCRs in Neuroscience Diverse signaling mechanisms

GPCR Activation and Signaling Targeting biased signaling by PAR1: Function and molecular mechanism of

great importance in order to better understanding human physiology as well as to dissect the molecular mechanism

ERK signaling, tightly regulated through feedback mechanisms and spatial localisation within the cell

B GPCR agonist binding Structural and Molecular Insights into GPCR Function Structure and Molecular Mechanism

function of the SNARE protein complex in neurotransmitter release has been well characterized, the mechanisms

Cardiology, Endocrinology, and Taste RGS4 controls airway hyperresponsiveness through GAP-independent mechanisms

Classified GPCR News from February 5th to 11th, 2024 GPCR Activation and Signaling Constitutive activation mechanism

Structural and Molecular Insights into GPCR Function The activation mechanism and antibody binding mode

Dissecting the molecular basis for the modulation of neurotransmitter GPCR signaling by GINIP Molecular mechanism

adenosine receptor activation by a G protein and constitutively activating mutations Distinct activation mechanisms

Dynamics Simulations Indicated the Involvement of a Conserved Polar Signaling Channel in the Activation Mechanism

co-regulated by the noncoding RNA NEAT1 in Alzheimer's disease Parenting behaviors in mice: Olfactory mechanisms

Endocrinology, and Taste Rap1A Modulates Store-Operated Calcium Entry in the Lung Endothelium: A Novel Mechanism

searching Heterotrimeric G protein signaling without GPCRs: the Gα-binding-and-activating (GBA) motif Mechanisms