Search Results
154 items found for "Lauren T May"
- The power of many: Multilevel targeting of representative chemokine and metabolite GPCRs in personalized cancer therapy
Specifically, the review highlights five GPCRs able to orchestrate tumor immunobiology at three main
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
The alterations in macrophage phenotype observed in Gpr101 deficient macrophages were maintained following
- Interrogating Multiscale Receptors Functions in Space
In particular, D2R is the main pharmacological target of antipsychotic drugs prescribed for schizophrenia
- Ep 62 with Dr. Sai Prasad Pydi
The main target of Dr.
- GPR68-ATF4 signaling is a novel prosurvival pathway in glioblastoma activated by acidic extracellular microenvironment
glioblastoma cell lines tested, irrespective of genetic and phenotypic heterogeneity, or resistance to the mainstay Authors Charles H Williams , Leif R Neitzel , Jessica Cornell , Samantha Rea , Ian Mills , Maya S Silver
- Ep 58 with Dr. Juan José Fung
His current work is mainly focused on screening and assay development to bridge the gap between in vitro
- Interaction with the cell adhesion molecule NEGR1 affects mGluR5 cell signalling
Ribeiro main scientific contributions include the study of the mechanisms involved in neurodegeneration
- GPCR Retreat | Dr. GPCR Ecosystem
The main goal of the GPCR Retreat is to provide a venue for students, post-doctoral fellows, and principal
- Ep 133 with Dr. Richard Premont
For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling
- Ep 123 with Dr. Lukas Grätz
As a developer, and more recently the lead developer of GPCRdb my day-to-day work centers around the maintenance
- CB2 stimulation of adipose resident ILC2s orchestrates immune balance and ameliorates type 2 diabetes mellitus
Group 2 innate lymphoid cells (ILC2s) play a critical role in maintaining adipose homeostasis via the
- Ep 111 with Chloe Hicks
Atypical Chemokine Receptor 3 (ACKR3), a receptor which does not couple to G protein and has been shown to maintain
- Ep 131 with Dr. Richard Premont
For this, we have worked in three main areas: the regulation of G protein-coupled receptor signaling