With this high-resolution, dynamic view of GPCR activation, scientists can better tackle diseases by

Schizophrenia Sphingosine 1-phosphate receptor subtype 1 (S1P1) activity in the course of Alzheimer's disease

whether these CB1 receptors contribute to pathways underlying skeletal muscle biological function and disease

Nordisk stops Ozempic kidney trial after early signs of success Sosei and PharmEnable extend neurological disease

Immunology CCR6 as a Potential Target for Therapeutic Antibodies for the Treatment of Inflammatory Diseases

participates in inflammatory and immune responses that have been found to mediate apoptosis in autoimmune disease

unveil new dimensions of GPCR functionality and offer innovative approaches to treating a wide range of diseases

extracellular ATP/adenosine dynamics in zebrafish models of alcoholic and metabolic steatotic liver disease

Specialized Pro-resolving Lipid Mediators and Resolution of Viral Diseases.

wakefulness LPA3 agonist-producing Bacillus velezensis ADS024 is efficacious in multiple neuroinflammatory disease

tyrosine kinase IGF1R and its associated GPCRs are co-regulated by the noncoding RNA NEAT1 in Alzheimer's disease

G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders.

neuroscience drugmaker Cerevel Therapeutics for $8.7 billion FDA approves two gene therapies for sickle cell disease

Adhesion GPCRs Adhesion G Protein-Coupled Receptor Gpr126 (Adgrg6) Expression Profiling in Diseased Mouse

Neuroimmune interplay during type 2 inflammation: symptoms, mechanisms and therapeutic targets in atopic diseases

Classified GPCR News from August 14 to 20, 2023 Adhesion GPCRs Amelioration of non-alcoholic fatty liver disease

next-generation sequencing, have enabled the uncovering of associations between GPCR genetic variants and diseases

agonism at the GLP-1R represents a promising strategy for optimizing therapeutic outcomes in metabolic diseases

Endocrinology, and Taste Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

A case for (mutant) G protein-coupled receptors Reviews, GPCRs, and more RGS2 and female common diseases

GPCRs in Neuroscience Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson's disease

G-protein coupled receptor-mediated vasocontraction in rat coronary arteries GPCRs involved in metabolic diseases

more The multifaceted functions of β-arrestins and their therapeutic potential in neurodegenerative diseases

midgut development in Drosophila Structure, ligands, and roles of GPR126/ADGRG6 in the development and diseases

Adhesion GPCRs Downstream signaling of the disease associated mutations on GPR56/ADGRG1.

screening of potential inhibitors of GPR52 using docking and biased sampling method for Huntington's disease

and design of 5-HT6 antagonists through assessment of ANN-QSAR models in the context of Alzheimer's disease

Financial Results Novartis Automates New Radioligand Therapy Production Plant Novartis’ Lutathera reduces disease