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185 items found for "Shunda Du"
- Ep 16 with Dr. Aaron Sato
During our time together, Aaron and I discussed how using Twist Bioscience’s proprietary technology to
- Agonists of galanin subtype 2 receptor may prevent pancreatic cancer and agonists of angiotensin II type 2 receptor may prevent colorectal cancer
II type 2 receptor may prevent colorectal cancer Published date June 24, 2024 Abstract "Pancreatic ductal
- Ep 17 with Dr. Yamina Berchiche
During the past 2 decades, my research mainly focused on chemokine receptor structure/function relationships presentation, I will walk you through my various career experiences and include the skills I learned during
- Ep 101 with Dr Caron Tribute Part 2
Caron and his family moved to Durham, NC in 1977, following receipt of his BSc in Chemistry from Laval He joined the faculty of Laval University School of Medicine in 1975 and then returned to join Duke’s Duke Professor until his death.
- Ep 49 with Dr. Sudha Shenoy
currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular Medicine, Duke Lefkowitz (Nobel Laureate, 2012) at Duke University. Dr. Sudha Shenoy on the web Duke University Personal Reflections and Words of Wisdom: Story From Dr.
- Investigating isoform switching in RHBDF2 and its role in neoplastic growth in breast cancer
because the proteolysis mechanism is an irreversible process that aids in regulating cellular growth during Speculatively, previous studies on gene expression analysis of RHBDF2 showed heterogenous behaviour during Nevertheless, it was noteworthy that during CTCs, the cub isoform switches back to the canonical isoform Therefore, it could be inferred that cub isoform functions during cancer initiation in EGFR signalling In contrast, during metastasis, where invasion is the primary task, the isoform switches back to the
- Ep 82 with Dr. Lauren M. Slosky
Caron at Duke University. Dr. advocate for trainees at all levels, she served as Service Chairperson and Interim President of the Duke
- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
Data on incident cases of EC and GC during 2004 to 2018 were obtained from the Golestan Population-based 95% CI: -7.8 to -2.2) and less marked nonsignificant trends for GC (EAPC = -1.4; 95% CI: -4.0 to 1.4) during
- Comparison of infectious complications with BCMA-directed therapies in multiple myeloma
During periods of treatment-emergent hypogammaglobulinemia, BsAb recipients had higher infection rates During periods of non-neutropenia, CAR-T recipients had a lower risk (HR 0.44, 95%CI 0.21-0.93, P = 0.032 Our results also suggest a higher infection risk during periods of hypogammaglobulinemia with BsAb, and
- Glucose and HODEs regulate Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway
primary metabolism as well as secondary metabolism, and further affects the growth of A. ochraceus during
- Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation
personalised GPCR-targeted nanomedicines, for the delivery of lethal drugs to tumour tissue before, during
- Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation
Authors Magdalena B Flak , Duco S Koenis , Maria Gonzalez-Nunez , Ana Chopo-Pizarro , Jesmond Dalli Tags
- Ep 144 with Dr Aurélien Rizk
During four years of postdoctoral research at ETH Zurich and the Paul Scherrer Institute in Switzerland They highlighted that while there was a time when biology lagged due to the lack of appropriate tools consideration to work on targets other than GPCRs, to which Aurelien Rizk explained that they chose GPCRs due They highlighted the strategic importance of planning in the biotech sector due to limited funds and They also discussed plans to offer a course with Terry, due to high interest.
- Ep 146 with Dr Michael Feigin
The discussion also covered the challenges they face in studying GPCRs due to their low expression levels Mike also spoke about his initial struggles during his Ph.D., such as a difficult model system and a G-protein coupled receptors (GPCRs) in breast cancer, identifying GPR161 as a potential drug target due Mike expressed his initial reluctance due to a lack of confidence and fear of not being ready. They also discussed the challenges they face in studying GPCRs due to their low expression levels and
- Ep 27 with Dr. Robert J. Lefkowitz
Duke Professor of Medicine and Professor of Biochemistry, Chemistry, and Pathology at the Duke University Thing Happened on the Way to Stockholm: The Adrenaline-Fueled Adventures of an Accidental Scientist Duke
- Ep 12 with Dr. Antonella Di Pizio
trained as a medicinal chemist in Italy, followed by a Ph.D. in computational medicinal chemistry, during
- Ep 119 with Tanishka S. Saraf
During my PhD, I learnt radioligand binding assays, behavioral assays, autoradiography, stereotaxic surgeries
- Ep 38 with Dr. Alexander S. Hauser
During his Ph.D. with David Gloriam at the Department of Drug Design and Pharmacology in Copenhagen,
- Ep 138 with Dr. Daniel Isom
to earn a Ph.D. in Molecular Biophysics from Johns Hopkins University, followed by postdocs at both Duke
- Ep 72 with Dr. Stuart Maudsley
was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz at Duke
- Ep 78 with Dr. Stuart Maudsley
was awarded a Howard Hughes Medical Institute Fellowship to train with Professor Robert Lefkowitz at Duke
- Ep 84 with Rosie Dawaliby
biochemistry of GPCR and the crucial role of the lipidic environment on their structure and function during
- Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
interactions drive pancreatic cancer cell invasion Published date March 21, 2023 Abstract " Pancreatic ductal
- Ep 69 with Dr. Stephen Ferguson
Caron at Duke University (1994-1997), where he and his colleagues investigated the role of G protein-coupled
- Delivery of US28 by incoming HCMV particles rapidly attenuates Akt activity to suppress HCMV lytic replication in monocytes
Inhibiting the dual phosphorylation of Akt prevented the lytic replication of US28Δ, and ectopic expression was necessary and sufficient to attenuate epidermal growth factor receptor (EGFR) signaling induced during Thus, particle-delivered US28 fine-tunes Akt activity by limiting HCMV-induced EGFR activation during
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
Here we show in the nematode-trapping fungus, Arthrobotrys flagrans, that both are achieved through a dual-function This dual localization of GprC in A. flagrans resembles the localization of the cannabinoid receptor The C. elegans ascaroside-sensing GPCR, SRBC66 and GPCRs of many fungi are also predicted for dual localization
- Dr. GPCR Symposia | Dr. GPCR Ecosystem
Increase the number of events during the calendar year to meet more frequently. 2.
- Ep 64 with Dylan Eiger
Back to podcast list Dylan Eiger About Dylan Eiger Dylan Eiger is currently an MD/Ph.D. student at Duke He received his B.S. in Chemistry from Duke University in 2016 where he worked in the lab of Dr.