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281 items found for "Structure Therapeutics"
- G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Aberrant hormone receptors regulate a wide spectrum of endocrine tumors
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- GprC of the nematode-trapping fungus Arthrobotrys flagrans activates mitochondria and reprograms fungal cells for nematode hunting
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Comparative analysis of the occupancy of Histone H3 Lysine 4 methylation in the cells treated with TGFβ and Interferonγ
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Efferocytes release extracellular vesicles to resolve inflammation and tissue injury via prosaposin-GPR37 signaling
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- High Metabolite Concentrations in Portal Venous Blood as a Possible Mechanism for Microbiota Effects on the Immune System, and Western Diseases
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- GPR176 Promotes Cancer Progression by Interacting with G Protein GNAS to Restrain Cell Mitophagy in Colorectal Cancer
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Chemokine Physiology in Cancer
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Posters | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Current affiliation: Department of Structural Biology, Genentech, South San Francisco, CA, USA" About Kordon "I am a postdoctoral scholar in the Araç Lab at The University of Chicago, studying the structure Utilizing synthetic antibody fragments, I aim to understand better the structural basis of the aGPCRs University of Copenhagen, Copenhagen, Denmark. (2) Department of Psychiatry and Molecular Pharmacology and Therapeutics Columbia University Vagelos College of Physicians and Surgeons, New York, USA; Division of Molecular Therapeutics
- Ep 144 with Dr Aurélien Rizk
technology platform deciphering cell signaling pathways combined with AI-based approaches to elucidate structure the company's ability to predict the residence time of a ligand and its potential correlation with a therapeutic Therapeutic Effect and Receptor Interactions Aurelien Rizk and Yamina had a detailed discussion about the importance of gaining more information about the therapeutic effect in patients or animals and the They also shared their preference for small molecule therapies over protein therapeutics.
- Flash News / DrGPCR
👅🔬 Researchers have unveiled the cryo-EM structure of TAS2R14 , the most promiscuous bitter taste receptor subtype-selective precision by combining allosteric modulation with light control, paving the way for new therapeutic essential additional elements to GPCR discovery programs that extend the discovery process and increase therapeutic
- CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- A GPCR-neuropeptide axis dampens hyperactive neutrophils by promoting an alternative-like polarization during bacterial infection
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3-L1 preadipocytes
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- G protein-coupled receptors related to autoimmunity in postural orthostatic tachycardia syndrome
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Deciphering the genetic landscape of lumpy skin disease: Unraveling variable virulence through comprehensive genome sequence analysis in India
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- GPR4 in the pH-dependent migration of melanoma cells in the tumor microenvironment
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Biochemical Mechanisms Underlying Location Bias in GPCR Signaling
Keith Moffat, he studied the structural mechanisms of bacterial photoreceptors using time-resolved Laue
- High expression of GPR50 promotes the proliferation, migration and autophagy of hepatocellular carcinoma cells in vitro
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Ep 145 with Dr John Janetzko
Daniel Kahne and Suzanne Walker studying the structure and function of the essential human enzyme, O-GlcNAc Over the course of my graduate work, I gained experience with structural mass spectrometry and protein position after the recording stops. • John will prioritize getting feedback from people outside his lab to structure
- Ep 87 with Dr. Bianca Plouffe
She identified the structural determinant controlling biased signaling of melatonin type 2 receptors
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Presentations Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics, Receptor Structure The shorter BAI1 isoforms lack most of the N-terminus and are very close in structure to the truncated graduate student, he worked in the EuGEF Research Group to identify novel prognostic biomarkers and therapeutic significant tissue-specific mRNA processing that results in holoreceptors with unique and variable N-terminal structures Clearly, a new, less toxic therapeutic is needed.
- CCL5-producing migratory dendritic cells guide CCR5+ monocytes into the draining lymph nodes
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P1 signaling axis
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Observational Study of Repeat Immunoadsorption (RIA) in Post-COVID ME/CFS Patients with Elevated ß2-Adrenergic Receptor Autoantibodies-An Interim Report
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
- Phase 1/2 study of sorafenib added to cladribine, high-dose cytarabine, G-CSF, and mitoxantrone in untreated AML
GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs in Oncology and Immunology Structural
