activates PI3K/Akt/mTOR signal transduction pathways to mediate epithelial-mesenchymal transition (EMT), thereby Therefore, our findings demonstrated that GPR37 may represent a viable therapeutic target for NSCLC."

neuropeptide G protein-coupled receptors (GPCRs) regulate motivated behavior and how these receptors can be targeted

regulator of immune responses by controlling the functions of monocytes and dendritic cells and that targeting

Coffee Break 4 Read More Friday, November 3rd / 3:30 PM G Proteins and GPCRs in Cancer: Novel Precision Targeted Melanoma Poster Talk Victoria Rasmussen Rockefeller University Read More Friday, November 3rd / 4:35 PM Targeting

pathway of the ADGRA homolog Remoulade in Drosophila Dimitris Placantonakis Antibody-drug conjugates targeting point mutant knock-in mouse, H381S Jesse Stillwell Next Generation MBD2 inhibitors for Brain Cancer Therapy

Showcase your products, services, and research initiatives to a targeted audience.

ligand synaptamide ameliorated this effect of ethanol by counteracting on the cAMP system, the common target

Early applications included “targeted photo-crosslinking,” and more recently, the parallel development

Postdoctoral Position, Scientific Dynamics, and New Drug Targets Arthur shared his decision to undertake Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with

Postdoctoral Position, Scientific Dynamics, and New Drug Targets Arthur shared his decision to undertake Lastly, they discussed the progress of new drugs targeting specific receptors for various diseases, with

chemokine physiology across discrete cancer immune phenotypes are contrasted to existing chemokine-centered therapies

Essential information is needed to characterize a drug's profile aimed at therapy.

Usage of Lorazepam, which has off target agonism of GPR68, is linked to worse clinical outcomes for a

These mice can then be used to test dietary regimens, drugs, and adenoviral gene therapies for their

PLK1 inhibition with ONV in combination with DAC could be a potential therapy in R/R AML patients, particularly

Predicted rescue therapies were assessed in cell systems and mouse injury-dependent pneumonia models.

discussed the importance of the extracellular region of these receptors and its potential as a drug target

GPR97/ADGRG3 In Neutrophil Biology Tyler Bernadyn Next Generation MBD2 inhibitors for Brain Cancer Therapy Tyler Bernadyn on the web LinkedIn Next Generation MBD2 inhibitors for Brain Cancer Therapy Jesse Stillwell His project is drug discovery focused, with particular interest in use of a novel epigenetic therapy

collaborating with other postdocs in the lab to develop assays and improve the biochemistry of certain targets

GAIN-targeted antibodies, and cancer-associated mutations at the GAIN-7TM interface, alter holoreceptor