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207 items found for "cancer biology"
- 📰 GPCR Weekly News, January 1 to 7, 2024
receptor Methods & Updates in GPCR Research RediscMol: Benchmarking Molecular Generation Models in Biological NEW Research Laboratory Specialist Associate Postdoctoral Scientist Principal Investigator, In Vitro Biology
- 📰 GPCR Weekly News, June 12 to 18, 2023
GPCRs in Oncology and Immunology The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer
- 📰 GPCR Weekly News, October 23 to 29, 2023
extracellular calcium pathways Versatile lactate signaling via HCAR1: a multifaceted GPCR involved in many biological vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research Scientist In Vitro Biologist
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
Emerging Voices in GPCR Biology in Special Issue of Molecular Pharmacology GPCR Events, Meetings, and Postdoctoral Scholar – iPSC in cardiac and endothelial cell function Protein Biochemist/Structural Biologist
- Addex Therapeutics To Release Full-Year 2021 Financial Results And Host Conference Call On March 10
Tim Dyer , CEO, Roger Mills , CMO and Robert Lütjens , Head of Discovery Biology, will provide a business
- Glyco-sulfo hotspots in the chemokine receptor system
body of evidence proposes that O-glycosylation and sulfation are important PTMs in chemokine receptor biology Dissecting the biological relevance of these PTMs requires relevant cells expressing the chemokine receptor Further research will be needed to boost our understanding on the dynamics and biological relevance of
- 📰 GPCR Weekly News, December 18 to 31, 2023
via GPCR signaling cascade GPCR Binders, Drugs, and more Biased agonists of GPR84 and insights into biological Clinical Pharmacology 2026 GPCR Jobs NEW Postdoctoral Scientist NEW Principal Investigator, In Vitro Biology
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
This insight not only enhances our understanding of class B1 GPCR biology but also opens new avenues Current Opinion in Structural Biology, 2023. 80 : p. 102574. 2.
- Job Opportunity Spotlight #1: Principal Scientist, In Vitro Pharmacology
few years ago by some former colleagues and their description of the company was very intriguing: a biology
- Therapeutic validation of an orphan G protein-coupled receptor: The case of GPR84
, recent developments and use of GPR84 pharmacological tool compounds to study its broader role and biology
- Decoding GPCR Function: The Role of Mutagenesis in Rational Drug Discovery
Notably, innovations in structural biology, such as X-ray crystallography and cryo-electron microscopy While advancements in structural biology techniques like X-ray crystallography and cryo-electron microscopy
- 📰 GPCR Weekly News, February 13 to 19, 2023
SLAS 2023 B Building Biology in 3D Symposium. Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.
- 📰 GPCR Weekly News, September 11 to 17, 2023
Technician Senior Research Associate, In Vitro Pharmacology - Crinetics Pharmaceuticals Postdoc In Cell Biology Of Protein Trafficking Postdoctoral Fellow Researcher / Senior Researcher in Structural Biology Research
- Dynamic GPCR activation revealed through time-resolved Cryo-EM
This research not only deepens our understanding of a key biological process but also provides a valuable This highlights the power of advanced imaging techniques like cryo-EM in solving complex biological puzzles Beyond GPCRs, the methods and insights from this study can be applied to other fast, transient biological
- Novel Therapies for Cardiometabolic Disease: Recent Findings in Studies with Hormone...
The present review describes novel findings regarding the complex biology of the preproglucagon-derived
- Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR
will gain unique and valuable access to the Sosei Heptares compound library for its industry-leading biology
- Nuclear localization of histamine receptor 2 in primary human lymphatic endothelial cells
Therefore, it is imperative to understand the precise molecular mechanism of H2R biology.
- Therapeutic validation of an orphan G protein‐coupled receptor
In this study Marsango et al. address two key questions in GPR84 biology and pharmacology: 1. how GPR84 and 2. which ligands can be used as tool compounds to study the function and biology of this receptor
- 📰 GPCR Weekly News, July 31 to August 6, 2023
fibroblast heterogeneity in fibroblast-associated diseases Ultrasensitive dose-response for asbestos cancer
- 📰 GPCR Weekly News, January 15 to 21, 2024
Pharmacology 2026 GPCR Jobs NEW Post-Doc position NEW Lead Researcher Senior Researcher in Structural Biology Fellow Research Laboratory Specialist Associate Postdoctoral Scientist Principal Investigator, In Vitro Biology
- Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...
present the PKC KO cell lines as more specific research tools to investigate PKC-mediated aspects of cell biology
- Anosmin 1 N-terminal domains modulate prokineticin receptor 2 activation by prokineticin 2
Prokineticins (PKs) exert their biological functions through the activation of the G protein-coupled Our data support the idea of a modulatory role of anosmin 1 in the biological effects controlled by the
- Discovery On Target, October 17-20, 2022, Boston, USA
target validation strategies for the discovery and development of novel therapeutic agents ranging from biologics
- Targeting Intracellular Allosteric Sites in GPCRs
Recent advances in structural biology and pharmacology have revealed the existence of allosteric sites Recent advances in structural biology have allowed researchers to visualize the binding of allosteric
- 📰 GPCR Weekly News, December 11 to 17, 2023
macrophage migration during tissue inflammation From odor to oncology: non-canonical odorant receptors in cancer
- Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
focused on the potentially clinical effects of psychedelics on human subjects tend to exclude sex as a biological profiles of the 5-HT2AR agonist DOI in C57BL/6J mice, and support the importance of studying sex as a biological
- 📰 GPCR Weekly News, October 30 to November 4, 2023
and Immunology Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer
- 📰 GPCR Weekly News, March 27 to April 4, 2023
- leadXpro and InterAx part of Fujitsu CaaS GPCR Events, Meetings, and Webinars SLAS 2023 Building Biology Progressive Technologies and Approaches Revealing Novel GPCR Biology and Drug Development Potential.