FRET and single-molecule microscopy, which allow them to directly observe signalling events in living cells Davide’s work has been published in prestigious scientific journals such as Nature, Cell, New England panels and committees, including the ENDO Annual Meeting Steering Committee and the MRC Molecular & Cellular

co-founder of InterAx Biotech, where he specializes in the development of a technology platform deciphering cell explored the potential of merging mathematical models with biology, the complexities of GPCRs within cells Cell Signaling and Cancer Metastasis Discussion Aurelien Rizk and Yamina Berchiche had a detailed conversation about the intricacies of cell signaling and chemokine receptors. Yamina shared her research experience, emphasizing the fascination of understanding how cells respond

Our laboratory is interested in the role of NMDA receptors not only on neurons, but also on other cells of the brain such as astrocytes, oligodendrocytes, and endothelial cells.

Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive

Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell of PAR signaling is critical for proper temporal and spatial dynamics of signaling and appropriate cellular acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the Trejo’s research program is to gain a thorough and mechanistic understanding of processes that control cell of PAR signaling is critical for proper temporal and spatial dynamics of signaling and appropriate cellular acquired critical expertise, and rigorous approaches to examine PAR1 function using human cultured cells

Ecosystem and beyond About Monserrat Avila Zozaya "My doctoral research was focused on investigating the cellular focuses on understanding the molecular mechanisms of adhesion GPCRs (aGPCRs) in lymphatic endothelial cells (LECs), a cellular model with unique junction arrangements where aGPCRs are mainly unexplored. " Monserrat

She has expertise in cell biology, pharmacology, translational medicine, oncology, immuno-oncology, immunology Previously, she held the position of Vice President of Cell Biology & Pharmacology, at Bristol-Myers She has extensive experience working with Biologics, and Antibody Drug Conjugates as well as experience

Simone Prömel Simone Prömel is currently a professor of cell biology at the Heinrich Heine University of action of Adhesion GPCRs and found that they do not only mediate classical G protein signals into cells

developed expertise over the past two decades studying structure/function relationships of GPCRs using live-cell Her work focused on chemokine receptors, members of the GPCR family that control cell movement in the Monserrat Avila Zozaya I did a PhD in cell biology at CINVESTAV, Mexico. My long-term interest is focused on understanding the mechanisms mediated by GPCRs at the cellular communication

Fan is currently an associate professor of Pharmacology and Pathology and Cell Biology at Columbia University

moved to Mexico City to establish himself as an independent investigator integrating the department of Cell Boucard´s lab focuses on molecular and cellular mechanisms underlying the function of adhesion GPCRs as various alternatively spliced isoforms thus potentially resulting in differential modulation of cell

His studies led to new concepts in the GPCR field, such as the activation of cell surface receptors by

Protein-Coupled Receptors Cheng-Chih Hsiao ADGRG1/GPR56 regulates survival of terminally differentiated CD8+ T cells compact multidomain module of fourteen domains which regulates signaling Vasiliki Karagiannakou A single cell Axons Monserrat Avila Zozaya The ADGRF5/GPR116 receptor is a key regulator of lymphatic endothelial cell GPR116 Willem Berend Post The Adhesion GPCR Latrophilin Interacts With The Notch Pathway To Control Germ Cell Role Of CELSR1 (ADGRC1) In Breast Cancer Emmanouil Kyrloglou GPR124 Mediates Adhesion Of Leukemic Stem Cells

Investigation, Molecular Pharmacology, British Journal of Pharmacology, and American Journal of Physiology-Cell

of Anders Nordström (Umeå, Sweden), I broadened my methodical and scientific horizon and focused on cellular Our ultimate goal is to understand their role in immune cell function and cancer cell metabolism. " Dr acknowledged the difficulty of distinguishing between different compounds and the effect of media on the cellular Yamina suggested the possibility of using native cells with optimized media, but Claudia highlighted

extracellular regions (ECRs) with nine cadherin repeats and a variety of adhesion domains which couple cell CELSRs regulate planar cell polarity, including the closure of the neural tube. Despite numerous cell and animal studies, molecular details on CELSR proteins are sparsely available, We employ cellular assays with full-length CELSR1 and truncation constructs to assess the adhesive and We assign the N-terminal CADH1-8 module as necessary for cell adhesion and we show the C-terminal CAHD9

We have developed an array of fluorescent biosensors to map kinase activity in living cells and are exploring

Sudha Shenoy is currently an Associate Professor in Medicine & Cell Biology in the Division of Cardiovascular

research in his laboratory focuses on how organisms perceive and respond to environmental stress though cell

learned gene synthesis, cDNA cloning, site-directed mutagenesis, and heterologous expression in mammalian cells suppression method to genetically encode unnatural amino acids into membrane proteins expressed in mammalian cell

Amynah did her undergrad research measuring IP3 in airway smooth muscle cells and completed a Ph.D. at

Experiments were then conducted using these cells which were divided into four groups of negative control Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call

team has made advances in the understanding of how an orphan GPCR exerts its effects both in vitro (cell expertise to establish a research program that takes orphan GPCRs from ‘locked’, inaccessible receptors to well-characterized

University of California, San Francisco with Professor Mark von Zastrow where she identified novel core cellular Her research focuses on understanding the fundamental cell biological mechanisms regulating GPCR activity

to reveal the spatial and temporal requirements for GPCR activation of signaling pathways related to cell

Jawaharlal Nehru University in India and it was during a biochemistry class where he learned about cell

After switching to biotech, Murat has built cell imaging software and lab robots to accelerate cancer