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180 items found for "pediatric tumors"
- Co-activation of GPCRs facilitate GIRK-dependent current
One potent form of inhibition is mediated by the activation of two inhibitory G protein-coupled receptors
- GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization...
The inhibitors of GPCR, ERK1/2, phagocytosis, and clathrin-mediated endocytosis (CME) as well as siRNA
- GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between ...
This communication involves the ligand-mediated control of cell surface receptors that then direct their
- Targeting Intracellular Allosteric Sites in GPCRs
hand, positive allosteric modulators that target intracellular allosteric sites can enhance β-arrestin-mediated NTSR1, provides valuable insights into how allosteric modulation can selectively enhance β-arrestin-mediated
- Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors
"The effects of the neurohormone melatonin are mediated by the activation of the GPCRs MT1 and MT2 in
- Unlocking Cell's Secrets: Spontaneous β-Arrestin-Membrane Preassociation Drives Receptor-Activation
receptor internalization via interaction with the adaptor protein 2 (AP2) and clathrin heavy chain mediating Molecular mechanism of GPCR-mediated arrestin activation.
- Canonical chemokine receptors as scavenging “decoys”
G. et al. 2000), becoming incapable of promoting cell migration, a phenomenon which is likely to be mediated
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
lifetime to optimise a prototypical animal opsin for optogenetic applications Imaging flow cytometry of tumoroids June 2 - 7, 2024 | Chemotactic Cytokines NEW June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- Melatonin MT 2 receptor is expressed and potentiates contraction in human airway smooth muscle
Numerous physiological effects of melatonin are mediated via its specific G protein-coupled receptors
- Involvement of various chemokine/chemokine receptor axes in trafficking and oriented locomotion ...
cells in multiple sclerosis patients Multiple sclerosis (MS) is a specific type of chronic immune-mediated
- 📰 GPCR Weekly News, June 12 to 18, 2023
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA.
- 📰 GPCR Weekly News, October 9 to 15, 2023
Adhesion GPCRs Piconewton Forces Mediate GAIN Domain Dissociation of the Latrophilin-3 Adhesion GPCR
- Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered
GPCRs, known for their involvement in a myriad of physiological processes, mediate mostly signaling through
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
nanoparticles in the range of μg/L in C. elegans The aim of this study was to identify Gα proteins mediating
- 📰 GPCR Weekly Buzz: Exciting Schedule Shifts for Principles of Pharmacology I & II | August 12-18, 2024
neuroprotective and neurogenic properties GPCRs in Oncology and Immunology Chemoattractant receptor signaling in humoral
- 📰 GPCR Weekly News, January 16 to 22, 2023
Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation.
- 📰 GPCR Weekly News - January 9 to 15, 2023
The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream
- 📰 GPCR Buzz: August 5-11, 2024 | Top Highlights from DrGPCR University!
subcellular signaling Striatal serotonin release signals reward value Ciliary length variations impact cilia-mediated
- 📰 GPCR Weekly News, August 14 to 20, 2023
diverse cancer cells GPCRs in Neuroscience Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated
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diabetes treatment GPCRs in Neuroscience Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated
- 📰 GPCR Weekly News, July 24 to July 30, 2023
G protein-coupled receptor-mediated membrane targeting of PLCγ2 is essential for neutrophil chemotaxis
- 📰 GPCR Weekly News, November 6 to November 12, 2023
antagonists Larixol is not an inhibitor of Gαi containing G proteins and lacks effect on signaling mediated
- 📰 GPCR Weekly News, May 20 to 26, 2024
Sciences as a Key to Success in Drug Discovery’ June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, March 11 to 17, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- Discover the Hottest GPCR News of the Week: Oct 7-13, 2024!
GPCR mechanosensing Postdoctoral Position GPCR Activation and Signaling Diverse pathways in GPCR-mediated
- 📰 GPCR Weekly News, February 26 to March 3, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- Transmembrane domains of GPCR dimers – a novel hot spot for drug discovery
efficacy usually depends on a pathway (G protein or β-arrestin), whereas side effects are normally mediated
- 📰 GPCR Weekly News, June 26 to July 2, 2023
GPCRs in Neuroscience Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different