compartments and signaling pathways associated with GPCRs holds promise for the development of novel therapeutic Insights into Nuclear G-Protein-Coupled Receptors as Therapeutic Targets in Non-Communicable Diseases GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic

; understanding the role of DNAJC13 in GPCR trafficking could profoundly affect the development of therapeutic

These therapeutic strategies could greatly impact the treatment of CVD with unprecedented benefits which

years to uncover the mechanisms of disease before they can even dare to contemplate the development of therapeutic

These findings indicate the potential of inhibiting MC4R homodimerization as a therapeutic target to

These insights will facilitate further development of therapeutic agents targeting the DOR.Communicated

Matt Barnes appointed President of Heptares Therapeutics Ltd., and Head of UK R&D Tokyo, Japan and

It is a therapeutic target because it plays a role in thermogenesis, lipolysis, and bladder relaxation

consequently activated signaling pathways, and also may shed light on the development of more effective new therapeutics

their appearance on the (illicit) drug market, e.g. as new psychoactive substances, their potential therapeutic

Industry News Design Pharmaceuticals has a new website Confo Therapeutics Announces Global Licensing Antiverse raises €2.8M for its computational antibody drug discovery platform Antiverse identifies therapeutic

September 2022 "G protein‐coupled receptors (GPCRs) are valuable therapeutic targets for many diseases

PTHR signaling that could be extended to GPCRs to expedite discoveries of small molecules as novel therapeutic

substantial participation in a wide variety of processes of human pathophysiology and are one of the main therapeutic

PTH-related protein (PTHrP) ligands and analogues for their pharmacologic activities and potential therapeutic

kinetic studies "G protein-coupled receptors (GPCRs) are an important receptor superfamily and common therapeutic

theoretically offer several advantages compared to orthosteric ligands when considered as potential therapeutic other GPCR-regulated systems such as free fatty acid receptors (FFARs), now regarded as targets for therapeutic

Bioscience Launches Revelar Biotherapeutics to Develop and Commercialize Novel COVID-19 and Other Antibody Therapeutics

stage pharmaceutical company focused on the discovery, development, and commercialization of novel therapeutics

2022 "The glucagon-like peptide-1 receptor (GLP-1R) plays a key role in metabolism and is an important therapeutic

Our results suggest that strategies to selectively target OGR1 expression may represent a novel therapeutic

Overall, our work reveals insight into PI3Kγ regulation and identifies sites that may be exploited for therapeutic

Biased pharmacological modulators provide potential therapeutic benefits, including greater pharmacodynamic

discrete and separable effects and provide proof of concept for the development of safer GPCR-targeting therapeutics

2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), is receiving renewed attention for their potential therapeutic

Pc(4-4) may become a promising candidate for future therapeutic cancer treatment."

Our results suggest that GPR15/GPR15L have a pathogenic role in RA and their antagonizing could be a therapeutic

regulating the PI3K/AKT/GSK-3β and MEK/ERK pathways in amygdalae of male mice, implicating a potential, therapeutic