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228 items found for "Cancer Research UK"
- Differences across sexes on head-twitch behavior and 5-HT2A receptor signaling in C57BL/6J mice
understanding of psychedelic pharmacology is derived from rodent models, but most of this preclinical research mice, and support the importance of studying sex as a biological variable in preclinical psychedelic research
- Use of CRISPR/Cas9-edited HEK293 cells reveals that both conventional and novel protein kinase C...
Our PKC KO cell lines expand the repertoire of KO HEK293A cell lines available to research GPCR pharmacology isozymes generally lack specificity and/or potency, we present the PKC KO cell lines as more specific research
- 📰 GPCR Weekly News, November 6 to November 12, 2023
migration of human T cells by directing GPCR and lipid second messenger signaling Methods & Updates in GPCR Research 12 - 17, 2026 | 20th World Congress of Basic and Clinical Pharmacology 2026 GPCR Jobs NEW Post-Doc Research Associate NEW Postdoctoral Fellow Research Scientist/Postdoctoral Associate in Computational Chemistry
- 📰 GPCR Weekly News, July 24 to July 30, 2023
Lukas Grätz, David Gloriam, and Gunnar Schulte’s research on Unveiling pathway selectivity in Frizzleds Methods & Updates in GPCR Research Strategies for acquisition of resonance assignment spectra of highly Robert Lefkowitz Lab Senior Research Specialist - Natural Sciences - Surgery Senior Scientist- Membrane
- Novo Nordisk moves to strengthen obesity efforts
Under the joint research plan, the Danish giant will work with EraCal to identify novel drug targets
- A cryptic mode of GPCR regulation revealed
October 2022 "Over three decades of research have provided thorough insights into G protein-coupled receptor
- X4 slashes pipeline, lays off staff just three weeks after netting a $55M PIPE
The Boston biotech revealed Wednesday afternoon that it would downsize its research to focus on its lead
- 📰 GPCR Weekly News
impairs growth of patient-derived xenografts of colorectal carcinoma in mice Methods & Updates in GPCR Research Interactions in the Serotonin 1A Receptor Microenvironment Industry News Addex and Indivior Extend Research
- Tectonic Therapeutic Strengthens Leadership Team
therapies (G-Protein Coupled Receptors), today announced the promotion of Senior Vice President, Head of Research
- Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca 2+ Sensing but...
Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR)."
- 📰 GPCR Weekly News, December 18 to 31, 2023
mediated neuroprotective mechanism through autophagy-mediated NLRP3 degradation Methods & Updates in GPCR Research Principal Investigator, In Vitro Biology NEW Associate Scientist Postdoctoral Scholar - O’Neill Lab Junior Research Scientist Postdoctoral Fellow Post-Doc Research Associate Assistant/Associate Professor Explore Dr.
- 4GPCRnet, September 26-29, 2022. Leipzig, Germany
Four of the biggest European networks on GPCR research (COST Actions Adher’n Rise and ERNEST plus DFG-funded
- Dr. Adriano Marchese - Dr. GPCR Podcast
Learn about his remarkable career and research in #GPCR signaling and trafficking.
- Neurotransmitters: Potential Targets in Glioblastoma
neurotransmitter receptors have shown great potential for inhibiting GBM growth and development, requiring further research
- Molecular insights into psychedelic drug action
desire for additional approaches to mental health care, incremental progress in basic and clinical research
- Molecular targets of psychedelic-induced plasticity
August 2022 "Psychedelic research across different disciplines and biological levels is growing at a
- Septerna emerges with $100M to spark 'second golden age' of prolific drug target GPCR with ...
Better known as GPCR, the fruitful research space has led to more than 700 approved drugs over previous Nobel laureate Robert Lefkowitz , M.D., has 50 years of experience with the target and analogizes the search
- Unlocking the Therapeutic Potential of Previously Undruggable GPCRs
Significant resources have been invested into the search for small molecule modulators of small protein for a number of inflammatory diseases including atherosclerosis, scleroderma, multiple sclerosis and cancer The Future of GPCR Research GPCRs are a very important class of drug targets, but despite historical Orion has entered a strategic research collaboration with Peptilogics, a US-based AI drug discovery company and efficiently advance a diversified portfolio of GPCR-targeted drug candidates for the treatment of cancer
- Michel Bouvier appointed Knight of the Ordre national du Québec
Michel Bouvier , Chief Executive Officer of IRIC, Principal Investigator of the Molecular Pharmacology Research
- Domain Therapeutics Raises $42m Series A Financing
STRASBOURG, France & MONTREAL- Domain Therapeutics , a biopharmaceutical company specializing in the research
- GPCR Therapeutics Expands Scientific Advisory Board
Jon Wigginton will provide scientific expertise to support the company’s research and clinical development
- 📰 GPCR Weekly News, October 23 to 29, 2023
Genes in Glioblastoma through Transcriptomics and Single-Cell Technologies Methods & Updates in GPCR Research Pharmaceuticals Senior Director, In vitro pharmacology - Crinetics Pharmaceuticals In vivo Antibody Discovery Research
- Community guidelines for GPCR ligand bias: IUPHAR review 32
The guidelines will aid consistency and clarity, as the basic receptor research and drug discovery communities
- Exploring pharmacological inhibition of G q/11 as an analgesic strategy
Previous research showed that activation of Gq/11 proteins by G-protein coupled receptors has pro-nociceptive
- Adhesion GPCR Consortium Newsletter - May 2024
Investigación y de Estudios Avanzados del IPN (Cinvestav) How did you become involved in adhesion GPCR research What challenges will researchers overcome in the next 10 years? AB: The next workshop will likely bring together some of the hottest adhesion GPCR research going on
- Class B1 GPCR Dimerization: Unveiling Its Role in Receptor Function and Signaling
Research using techniques like bioluminescence resonance energy transfer (BRET) and fluorescence resonance In summary, dimerization in class B1 GPCRs is an emerging area of research that has far-reaching implications
- SLAS2022 International Conference and Exhibition
Don't miss the chance to present your innovative research at this year's conference.
- Hear the sounds: the role of G protein-coupled receptors in the cochlea
The research of GPCRs in the cochlea is essential for the understanding of the cochlea development, hearing