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467 items found for "GPCR therapeutics"

  • Ep 59 with Dr. Nicola J. Smith

    GPCR Podcast << Back to podcast list Dr. Nicola J. Smith About Dr. Nicola J. Smith Dr. Nicola J Smith is an expert in molecular pharmacology with a track record in exploring GPCR structure-function Smith’s team has made advances in the understanding of how an orphan GPCR exerts its effects both in , named GPCR-CoINPocket. from ‘locked’, inaccessible receptors to well-characterized and understood ‘unlocked’ therapeutic targets

  • A positive Allosteric Modulator of M1 Acetylcholine Receptors Improves Cognitive Deficits in Male and Female Alzheimer’s Mice

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to He received the Canadian Society of Pharmacology and Therapeutics Postdoctoral and Publication awards along with many Young Scientist Awards from the American Society for Pharmacology and Experimental Therapeutics GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

  • Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte The Department’s strengths lie in GPCR signal transduction and neuroscience, and she has expanded it GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

  • Ep 81 with Dr. Christel Menet

    GPCR Podcast << Back to podcast list Dr. Christel Menet About Dr. I then started my career at Evotec before moving to Domain Therapeutics (called Faust pharmaceutical chemistry. 6 years ago I decided to take on a new challenge by taking the position of CSO at Confo Therapeutics Christel Menet on the web Hyphen Projects GPCRS Drug Discovery Confo Therapeutics LinkedIn Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

  • Ep 83 with Dr. Jean-Philippe Pin

    GPCR Podcast << Back to podcast list Dr. Jean-Philippe Pin About Dr. biosensors, cryo-EM, photoswitchable ligands, and nanobodies as pharmacological tools and potential therapeutic His studies led to new concepts in the GPCR field, such as the activation of cell surface receptors by intracellular proteins; the regulation of GPCRs by both negative and positive allosteric modulators, and the asymmetric functioning of GPCR dimers.

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  • Ep 19 with Dr. Fiona Marshall

    GPCR Podcast << Back to podcast list Dr. Fiona Marshall About this episode Fiona Marshall got fascinated with GPCRs after attending a lecture An expert in GPCR biology, Fiona published the first description of the cloning and structural requirements As a co-founder of Heptares Therapeutics , now called Sosei Heptares , a GPCR-focused drug discovery GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

  • Ep 109 with Dr. Katarina Nemec

    GPCR Podcast << Back to podcast list Dr. Katarina Nemec About Dr. I aim to discover new therapeutic approaches, and druggable molecules or refine canonical drug targets while performing various cell-based experiments to understand the binding, activation, and signaling of therapeutically relevant GPCRs. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs

  • Ep 84 with Rosie Dawaliby

    GPCR Podcast << Back to podcast list Dr. Rosie Dawaliby About Dr. Rosie Dawaliby "I’m an expert in early-stage drug discovery, targeting membrane proteins, especially GPCR I have developed my expertise in the field of pharmacology and biochemistry of GPCR and the crucial role In 2016, I joined a company that specialized in therapeutic candidate discovery targeting GPCR ( Confo Therapeutics ) as a team and project leader for antibody discovery for metabolic and inflammatory diseases

  • Ep 56 with Dr. Adriano Marchese

    GPCR Podcast << Back to podcast list Dr. Adriano Marchese About Dr. Adriano’s research has contributed to our understanding of the role that ubiquitin plays in GPCR signaling His lab has shown a role for -arrestins and PTMs in GPCR trafficking and signaling and has leveraged The ultimate goal of Adriano’s research is to target novel aspects of GPCR signaling for therapeutic GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

  • Ep 122 with Dr. Nicolas Gilles

    GPCR Podcast << Back to podcast list Dr. Nicolas Gilles About Dr. Nicolas Gilles "Dr. He is pioneering the investigation of animal toxins acting on GPCRs, the largest therapeutic target class His strongest expertise lies in therapeutic target identification and all the steps from venom manipulations pharmacological properties of these new ligands are deemed exceptional, a lead optimization is realized and its therapeutic GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs

  • Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to schedule Inhibition of Relaxin Autocrine Signaling Confers Therapeutic Vulnerability in Ovarian Cancer Several of these targets are being developed for potential new therapeutic strategies in ovarian and GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires 22nd GPCR Retreat Sponsored by

  • Ep 05 with Dr. Terry Hébert

    GPCR Podcast << Back to podcast list Dr. Terry Hébert About this episode Dr. Terry Hébert is a Professor within the Department of Pharmacology & Therapeutics at McGill University Much of his work is based on GPCR signaling in the context to cardiovascular diseases. on the web Terry Hébert | Institute of Health Sciences Education Hébert Lab LinkedIn Hébert Lab The GPCR GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand

  • Dopamine-Mediated Motor Recovery after Ischemic Stroke

    Retreat 2023 About Program Registration Logo Contest Committee Sponsors GPCR Retreat Program < Back to We hope our research will aid in the development of new therapeutic interventions for the alleviation GPCR Previous Event Next Event Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec Great Lakes GPCR Retreat and Club des Récepteurs à Sept Domaines Transmembranaires du Québec 22nd GPCR Retreat Sponsored by

  • Neutrophils are itching to specialize

    < GPCR News < GPCRs in Oncology and Immunology Neutrophils are itching to specialize Published date February Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs and molecular insights into GPCR function GPCR Activation and Signaling More from Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • G protein-coupled receptor-mediated signaling of immunomodulation in tumor progression

    < GPCR News < GPCRs in Oncology and Immunology G protein-coupled receptor-mediated signaling of immunomodulation Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Stable Binding of Full-Length Chemerin is Driven by Negative Charges in the CMKLR1 N-terminus

    < GPCR News < GPCRs in Oncology and Immunology Stable Binding of Full-Length Chemerin is Driven by Negative Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells

    < GPCR News < GPCRs in Oncology and Immunology The pyruvate-GPR31 axis promotes transepithelial dendrite Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Autocrine proteinase-activated receptor signaling in PC3 prostate cancer cells

    < GPCR News < GPCRs in Oncology and Immunology Autocrine proteinase-activated receptor signaling in PC3 Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Protease-Activated Receptor-1 IgG Autoantibodies in Patients with COVID-19

    < GPCR News < GPCRs in Oncology and Immunology Protease-Activated Receptor-1 IgG Autoantibodies in Patients News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Short-chain fatty acids and cancer

    < GPCR News < GPCRs in Oncology and Immunology Short-chain fatty acids and cancer Published date December News Coming soon Become a Contributor Classified GPCR News GPCR Jobs Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs , and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Ep 69 with Dr. Stephen Ferguson

    GPCR Podcast << Back to podcast list Dr. Stephen Ferguson The History of the Great Lakes GPCR Retreat with Dr. Stephen Ferguson About Dr. Brian Collier in the Department of Pharmacology and Therapeutics at McGill University (1994). GPCR Ecosystem Great Lakes GPCR Retreat on the web 21st Great Lakes GPCR Retreat More about previous GPCR Retreat meetings Dr.

  • G Protein-coupled Receptor-mediated Membrane Targeting of PLCγ2 is Essential for Neutrophil Chemotaxis

    < GPCR News < GPCRs in Oncology and Immunology G Protein-coupled Receptor-mediated Membrane Targeting Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Aberrant hormone receptors regulate a wide spectrum of endocrine tumors

    < GPCR News < GPCRs in Oncology and Immunology Aberrant hormone receptors regulate a wide spectrum of News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Unveiling G-protein coupled receptors as potential targets for ovarian cancer nanomedicines: from RNA sequencing data analysis to in vitro validation

    < GPCR News < GPCRs in Oncology and Immunology Unveiling G-protein coupled receptors as potential targets Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Pan-cancer functional analysis of somatic mutations in G protein-coupled receptors

    < GPCR News < GPCRs in Oncology and Immunology Pan-cancer functional analysis of somatic mutations in Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • G protein coupled receptor transcripts in human immune cells and platelets

    < GPCR News < GPCRs in Oncology and Immunology G protein coupled receptor transcripts in human immune GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience insights into GPCR function GPCR Activation and Signaling More from Dr. GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

  • Intermediate-state-trapped mutants pinpoint G protein-coupled receptor conformational allostery

    < GPCR News < GPCRs in Oncology and Immunology Intermediate-state-trapped mutants pinpoint G protein-coupled News Coming soon Become a Contributor Classified GPCR News Call for GPCR papers GPCR Industry News Adhesion GPCRs GPCR Events, Meetings, and Webinars Reviews, GPCRs, and more GPCR Binders, Drugs, and more Methods & Updates in GPCR Research GPCRs in Neuroscience GPCRs in Cardiology, Endocrinology, and Taste GPCRs GPCR News and get weekly notifications about the GPCR field Share < Previous Next >

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