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189 items found for "Gene expression"
- Illuminating Functional Selectivity and Allosterism at GPCRs.
He has contributed to the generation of many intellectual property agreements and patents, and published
- Chemokine N-terminal-derived peptides differentially regulate signaling by the receptors CCR1 and CCR5
In contrast, none of the peptides generated a signal on CCR5, but a CCL3-derived tetrapeptide was a positive
- Metallo-protease Peptidase M84 from Bacillusaltitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
1 overexpression along with activating its downstream signaling effectors NF-κB and MAPK to promote excessive reactive oxygen species (ROS) generation.
- Ep 53 with Dr. Timo De Groof
Moreover, he is closely involved in multiple projects where he focuses on the generation of nanobodies
- GPCRs and fibroblast heterogeneity in fibroblast-associated diseases
This review highlights the importance of designing and adaptation of next-generation strategies such
- Ep 95 with Chris Langmead
Phrenix Therapeutics, a biotech spin-out from the Neuromedicines Discovery Centre that is developing next-generation
- About Us | Dr. GPCR Ecosystem
programs including the: Summit Virtual Cafe Listening to podcast episodes before these are released to the general
- Principles of Pharmacology in Drug Discovery I
In general, registrants will receive a comprehensive understanding of the unique science of pharmacology
- Principles of Pharmacology in Drug Discovery I
In general, registrants will receive a comprehensive understanding of the unique science of pharmacology
- Metabolic crosstalk: Extracellular ATP and the tumor microenvironment in cancer progression and therapy
extracellular ATP degradation contributes to immunosuppression by diminishing ATP-dependent activation and generating
- C5aR2 receptor: The genomic twin of the flamboyant C5aR1
function of the C5aR2 is actively debated in the context of C5aR1, even though both C5aR1 and C5aR2 are coexpressed The current study has attempted to close the gap by generating highly refined model structures of C5aR2
- Esophageal and gastric cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004 to 2018
The marked declines in EC incidence rates in Golestan relate to generational changes in its underlying
- Colorectal cancer incidence trends in Golestan, Iran: An age-period-cohort analysis 2004-2018
Conclusion: The increasing trends in CRC rates in Golestan are largely driven by generational changes
- GPCR Retreat Schedule 2023
Disease Ali Salahpour University of Toronto Read More Friday, November 3rd / 9:45 AM Pharmacological and Genetic Mice Khaled Abdelrahman The University of British Columbia Read More Friday, November 3rd / 2:10 PM Genetic
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
Database-driven data mining and networking were utilized to establish a general correlation between Jinqiancao
- GPCR Retreat 2023 | Dr. GPCR Ecosystem
We would like to thank all our Sponsors for their ongoing generous support of the meeting.
- Session V | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
University, Härtelstr. 16-18, D-04107 Leipzig 3 Rudolf-Schönheimer-Institute of Biochemistry, Division of General Medical Faculty, Leipzig University, Germany 2 Rudolf Schönheimer Institute of Biochemistry, Division of General
- Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity
was optimized through Fmoc-based solid phase peptide synthesis (SPPS) and a strategy to efficiently generate
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Demet was an undergraduate at Bilkent University in Turkey, where she majored in Molecular Biology and Genetics We utilize several genetically modified mouse models to investigate requirements for receptor activator
- Ep 140 with Dr Alix A J Rouault
We were pleasantly surprised by the interest generated by our scientific session, Dr.
- Ep 151 with Dr GPCR Board
served on the Steering Committee of the San Diego Supercomputer Center, and provided consultation for genetic