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204 items found for "Specialized pro-resolving mediators"
- Navigating the Signaling Network: RTK and GPCR Crosstalk Uncovered
GPCRs, known for their involvement in a myriad of physiological processes, mediate mostly signaling through The primary research question addressed in this study was: How do growth factors, specifically through The researchers focused on the phosphorylation of the G protein subunit Gαi at specific residues within The study revealed that the epidermal growth factor-induced phosphorylation of Gαi at specific residues The ability of growth factors to modulate G protein signaling through specific phosphorylation events
- GPCRs Are Optimal Regulators of Complex Biological Systems and Orchestrate the Interface between ...
This communication involves the ligand-mediated control of cell surface receptors that then direct their
- 📰 GPCR Weekly News, October 9 to 15, 2023
Adhesion GPCRs Piconewton Forces Mediate GAIN Domain Dissociation of the Latrophilin-3 Adhesion GPCR Receptor Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Parallel evolution of the G protein-coupled receptor GrlG and the loss of fruiting body formation in the social
- Free-Energy Simulations Support a Lipophilic Binding Route for Melatonin Receptors
"The effects of the neurohormone melatonin are mediated by the activation of the GPCRs MT1 and MT2 in
- 📰 GPCR Weekly News, June 12 to 18, 2023
CLIC4 Regulates Endothelial Barrier Control by Mediating PAR1 Signaling via RhoA.
- Involvement of various chemokine/chemokine receptor axes in trafficking and oriented locomotion ...
oriented locomotion of mesenchymal stem cells in multiple sclerosis patients Multiple sclerosis (MS) is a specific type of chronic immune-mediated disease in which the immune responses are almost run against the central
- Melatonin MT 2 receptor is expressed and potentiates contraction in human airway smooth muscle
Numerous physiological effects of melatonin are mediated via its specific G protein-coupled receptors which was reversed by the Gαi protein inhibitor pertussis toxin or knockdown of the MT2 receptor by its specific
- 📰 GPCR Weekly News, April 1 to 7, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
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regulators András D Tóth, Gábor Turu, and László Hunyady for their research on Functional consequences of spatial : dialing up and down neurotransmitter responses by G-protein regulators Functional consequences of spatial diabetes treatment GPCRs in Neuroscience Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated
- 📰 GPCR Weekly News, June 24 to 30, 2024
Promoter in Intron 17 The adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated
- 📰 GPCR Weekly News, May 20 to 26, 2024
Sciences as a Key to Success in Drug Discovery’ June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- Decoding β-Arrestins: from Structure to function
While some receptors selectively activate specific G protein families, others are more versatile, yielding diverse responses based on cell-specific G protein expression. Originally recognized for inhibiting G protein signaling, they also influence specific pathways such equally and arrestins can undergo different conformational changes for the binding to the same GPCR to mediate The observed variations in β-arrestin expression likely impact the composition and function of GPCR-mediated
- 📰 GPCR Weekly News, November 6 to November 12, 2023
apoptosis through binding to ADGRL1 and activating cAMP/PKA/CREB/BCL2 signaling pathway Deciphering specificity antagonists Larixol is not an inhibitor of Gαi containing G proteins and lacks effect on signaling mediated
- 📰 GPCR Weekly News, January 16 to 22, 2023
Soluble cyclase-mediated nuclear cAMP synthesis is sufficient for cell proliferation.
- 📰 GPCR Weekly News, August 14 to 20, 2023
diverse cancer cells GPCRs in Neuroscience Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated
- 📰 GPCR Weekly News - January 9 to 15, 2023
The molecular associations in clathrin-coated pit regulate β-arrestin-mediated MAPK signaling downstream
- Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the ...
nanoparticles in the range of μg/L in C. elegans The aim of this study was to identify Gα proteins mediating
- 📰 GPCR Weekly News, July 24 to July 30, 2023
GPCR Activation and Signaling Endosome positioning coordinates spatially selective GPCR signaling. G protein-coupled receptor-mediated membrane targeting of PLCγ2 is essential for neutrophil chemotaxis
- 📰 GPCR Weekly News, January 1 to 7, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, April 22 to 28, 2024
chimeric peptide ligand for NanoBiT complementation binding assays Generation of a deep mouse brain spectral Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, April 15 to 21, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 Breaking Down the Latest GPCR Discoveries: a Weekly Update (Nov 27-Dec 3, 2023)
June 2 - 7, 2024 | Chemotactic Cytokines NEW June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, July 1 to 7, 2024
., for their work on GRK specificity and Gβγ dependency determines the potential of a GPCR for arrestin-biased Specifically, the ideas discussed cover the complex pleiotropic behaviors of GPCRs and how these may protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets GRK specificity and signalling of the CB1, CB2, GPR18 and GPR55 cannabinoid receptors GPCRs in Neuroscience Neuron specific in the rat retrosplenial cortex Unveiling the therapeutic prospects of EGFR inhibition in rotenone-mediated
- 📰 GPCR Weekly News, June 26 to July 2, 2023
GPCRs in Neuroscience Fine-tuning GPCR-mediated neuromodulation by biasing signaling through different
- 📰 GPCR Weekly News, January 22 to 28, 2024
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, May 13 to 19, 2024
Sciences as a Key to Success in Drug Discovery’ June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated
- 📰 GPCR Weekly News, April 24 to 30, 2023
in Oncology and Immunology Stretch regulates alveologenesis and homeostasis via mesenchymal Gαq/11-mediated
- 📰 GPCR Weekly News, December 11 to 17, 2023
Exhibition June 2 - 7, 2024 | Chemotactic Cytokines June 9 - 14, 2024 | 2024 Phosphorylation and G-Protein Mediated