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452 items found for "Stefano Moro"
- Arginine 125 Is an Essential Residue for the Function of MRAP2
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- 📰 GPCR Weekly News, March 25 to March 31, 2024
Stay tuned for more updates. for exploration of GLP-1R ligand effects in pancreatic β-cells and neurons GPCR Binders, Drugs, and more Monitoring norepinephrine release in vivo using next-generation GRABNE sensors Reviews, GPCRs, and more
- Trevena Adds Seasoned Biopharma Commercial Executive to Senior Leadership Team
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- Exscientia is 10 years old this July!
#artificialintelligence #drugdesign #drugdiscovery" Read more at the source #DrGPCR #GPCR #IndustryNews
- High hedgehog signaling is transduced by a multikinase-dependent switch controlling the...
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- Reversible Photocontrol of Dopaminergic Transmission in Wild-Type Animals
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- Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex
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- Viral G Protein-Coupled Receptors Encoded by β- and γ-Herpesviruses
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- Adenosine receptor signalling in Alzheimer's disease
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- Search for safer pain relief advances with new engineered compounds
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- 📰 GPCR Weekly News
Hello Readers👋, We are working on bringing your the latest GPCR News more frequently directly in your GPCR Binders, Drugs, and more Persistent challenges in the development of an mGlu7 PAM in vivo tool compound
- Community guidelines for GPCR ligand bias: IUPHAR review 32
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- AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors
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- Adenosine receptor signalling in Alzheimer's disease
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- Exploring pharmacological inhibition of G q/11 as an analgesic strategy
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- GPR110, a receptor for synaptamide, expressed in osteoclasts negatively regulates osteoclastogenesis
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- TAS2R supports odontoblastic differentiation of human dental pulp stem cells in the inflammatory...
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- Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
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- Therapeutic validation of an orphan G protein-coupled receptor: The case of GPR84
developments and use of GPR84 pharmacological tool compounds to study its broader role and biology. " Read more
- Addex Reports 2022 Half Year and Second Quarter Financial Results and Provides Corporate Update
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- Structural insights into adhesion GPCR ADGRL3 activation and Gq, Gs, Gi, and G12 coupling
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- Dimerization of β2-adrenergic receptor is responsible for the constitutive activity subjected to inv
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- Targeting Intracellular Allosteric Sites in GPCRs
This allows for the fine-tuning of receptor activity, leading to more specific and safer drugs. Allosteric modulators targeting GPCRs can display one or more of the following pharmacological characteristics Advantages of targeting GPCRs allosteric sites Allosteric sites offer a more nuanced approach to modulating
- Crinetics Pharmaceuticals Announces Pricing Of Underwritten Common Stock Offering
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- Addex Therapeutics Completes Patient Enrollment For Dipraglurant Blepharospasm Phase 2 Clinical ...
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- Unveiling GPCR Priming: The Hidden Synergy in Cellular Signalling
priming is attributed to the formation of temporal non-cognate-GPCR conformational states, which enable more It challenges the traditional view of strict cognate G protein coupling and suggests a more dynamic interaction
- Orion Announces The Rapid Lead Optimization Of Ob-004 - A Ccr2 Antagonist
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- Domain Therapeutics and Explicyte enter partnership agreement in immuno-oncology
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