Here, we describe the most recent literature, with a primary focus on the past 5 years, on GPCR targets

analyzed in HCC patients (gene expression omnibus database (GEO) (GSE45436)) and detected in HCC cell line and the results showed that GPR50 was significantly up-regulated in HCC patients and CBRH-7919 cell line Gpr50 cDNA was transfected into HCC cell line CBRH-7919, and we found that Gpr50 promoted the proliferation Authors Weiming Zhao , Lingling Xi , Guoying Yu , Gaiping Wang , Cuifang Chang Source Contribute to the

Authors Ze Wu , Qiongqiong Jia , Boqun Liu , Lanlan Fang , Peter C K Leung , Jung-Chien Cheng Tags Invasion

Cell lines expressing EBI2 were established by transduction with HIV vectors. As the natural ligand for EBI2 is present in blood and lymphoid tissues, the constant EBI2 activation

form multimeric complexes with other GPCRs and characterized the relative size of the complexes in a live-cell PIE-FCCS can resolve membrane protein density, diffusion, and multimerization state in live cells at We probed CXCR4 and β2AR homo- and heteromultimerization in model cell lines and found that CXCR4 assembles CXCR4 multimers in MDA-MB-231 and HCC4006 cells to a higher degree than in COS-7 and CHO cells and in a ligand-dependent Authors Junyi Liang , Mohamed Seghiri , Pradeep Kumar Singh , Hyeon Gyu Seo , Ji Yeong Lee , Yoonjung

GPCR Podcast << Back to podcast list Dr. Tobi Langenhan About Dr. Tobi Langenhan "I studied medicine at the University of Würzburg, where I obtained my license to practice Tobi Langenhan on the web Langenhan Lab ORCID LinkedIn University of Leipzig Dr. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Prasenjit Saha About Dr. Specifically, I am interested in understanding dysregulated G-protein coupled receptor (GPCR) signaling linked Prasenjit Saha on the web Google Scholar Pubmed LinkedIn Dr. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Paul Insel About this episode Dr. at UCSD and has served as Editor or Senior Editor of numerous scientific journals, including but not limited GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

This expanded understanding of the role of GPCRs may shed light on the mechanisms underlying tumor progression

GPCR Podcast << Back to podcast list Gáspár Pándy-Szekeres About Gáspár Pándy-Szekeres " After a BSc I lived in Denmark, Poland, now I live in Hungary. I am married, I have two daughters. In my free time I like to play the guitar, sing and play board games. " Gáspár Pándy-Szekeres on the web LinkedIn University of Copenhagen ResearchGate Twitter Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

Authors Peter J P Croucher , Maya Ridinger , Pamela S Becker , Tara L Lin , Sandra L Silberman , Eunice

receptor (EGFR) belongs to the receptor tyrosine kinases family and overexpression of EGFR has been linked Conclusion: Our study is the first to shed light on the intricate relationship between SSTR2 and EGFR

GPCR Podcast << Back to podcast list Dr. Richard Premont About Dr. Richard Premont "Dr. University of New York) in 1990 and 1992, working with Ravi Iyengar on regulation/desensitization of the liver and in liver disease. Richard Premont on the web Google Scholar LinkedIn Dr. Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Nariman Balenga About Dr. Nariman Balenga on the web Researchgate Linkedin.com Google Scholar Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Adriano Marchese About Dr. Adriano Marchese on the web Twitter LinkedIn Google Scholar Website Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Stephane Angers About Dr. Stephane Angers Dr. His thesis work led to the development and application of light energy transfer methodology to study identified and characterized novel components of the Wnt signaling pathway and a new class of E3 ubiquitin ligases GPCR Ecosystem LinkedIn Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Exploring Career Paths in GPCR Research with Dr. Jacek Mokrosiński on the web ORCID ResearchGate LinkedIn Twitter Dr. They also highlighted the need for a work-life balance and the joy of a well-done job. They also highlighted the advantages of using LinkedIn as a tool for networking and the significance Thanks for listening to this podcast episode This short survey will help us understand your needs to

GPCR Podcast << Back to podcast list Dr. Graham Ladds About Dr. Graham Ladds on the web Twitter ResearchGate LinkedIn Google Scholar PubMed Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Katarina Nemec About Dr. Katarina Nemec on the web Babu Lab ResearchGate Google Scholar ORCID LinkedIn Twitter Dr. GPCR Thanks for listening to this podcast episode This short survey will help us understand your needs Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Jacob Lee & Jin Choe About this episode In this special episode Genemode on the web Website Jacob Lee on LinkedIn Jacob Lee on Dr. GPCR Ecosystem Jin Choe on LinkedIn Jin Choe on Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

developmental delays, intellectual impairment, visual impairments, and difficulties with daily tasks like Many children experience seizures that can be life-threatening. The Ramsey Lab Amy Ramsey on the web University of Toronto Pubmed Google Scholar LinkedIn Twitter Dr.

heat-shock activation pathway) that triggers expression of a suite of target genes while efficiently limiting In contrast, a linear no-threshold (LNT) dose-response relationship is expected for damage that accumulates

, BP , Beta chain , Bovine adrenal medulla peptide 8-22 , Bullous pemphigoid , C-C motif chemokine ligand volume in 1 second from baseline , Prurigo nodularis , SP , STAT , Sialic-acid-binding immunoglobulin-like

Registrants will learn: Essentials of measuring pharmacologic activity of ligands (affinity, efficacy Application of this knowledge to determine the mechanism of action of new GPCR ligands. Classes will be live from Zoom on Thursdays from 10 am to 11:30 am EST. Sessions will include a 1-hour live lecture plus 30 minutes of Q&A. What would you like to learn today?

express two to four members of the GRK family (GRK2, GRK3, GRK5, GRK6) simultaneously, but we have very limited all four GRK family members show increased chemotactic migration responses to a wide range of GPCR ligands

GPCR Podcast << Back to podcast list Nicole Perry-Hauser About Nicole (Nicki) Perry-Hauser I am a postdoctoral Mutations in aGPCRs have been linked to various neuropsychiatric phenotypes, and my work will provide Nicole (Nicki) Perry-Hauser on the web LinkedIn Research Gate Pubmed Dr. GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Caron Tribute Part 1 About Marc Caron Dr. Lee Limbird (1973) Dr. David Sibley (1988) Memories our panelists shared with us Thanks for listening to this podcast episode Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode

GPCR Podcast << Back to podcast list Dr. Paul Insel About this episode In 1975, Dr. used radioligand binding methods to dissect receptor function from the adenylyl cyclase activated by ligands GPCR Ecosystem Thanks for listening to this podcast episode This short survey will help us understand Listen and subscribe to where you get your podcasts. << Previous Podcast Episode Next Podcast Episode