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285 items found for "cAMP signaling"
- Systems Pharmacodynamic Model of Combination Gemcitabine and Trabectedin in Pancreatic Cancer Cells. Part II: Cell Cycle, DNA Damage Response, and Apoptosis Pathways
SPD model related to cell growth and migration, specifically the RTK-, integrin-, GPCR-, and calcium-signaling in Oncology and Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling
- Ep 47 with Dr Simone Promel Dr Ines Liebscher
different modes of action of Adhesion GPCRs and found that they do not only mediate classical G protein signals Today, she and her team are working on the questions of how Adhesion GPCRs integrate the different signals
- Ep 154 with Dr Badr Sokrat
projects, I studied the role of β-arrestin in G protein trafficking, the impact of GPCR ubiquitination on signaling My current research focuses on investigating GPCR signaling and trafficking in the context of inflammation I am particularly interested in spatial signaling bias or how GPCRs can redistribute to different subcellular compartments to trigger distinct signaling events. " Dr. Badr shared his passion for GPCR signalling and regulation, specifically in the context of pain and inflammation
- Ep 150 with Dr GPCR Team
communication, she is poised to make valuable contributions to the field and expand our understanding of GPCR signaling computational methods like molecular dynamics simulations and free energy landscape analysis to understand the signaling GPCR About Cam Sinh Lu Cam Sinh Lu is a PhD student at Monash Institute of Pharmaceutical Sciences, Monash molecular pharmacology, his research focuses on elucidating the molecular basis of membrane protein signalling Cam Sinh Lu on the web LinkedIn Dr.
- Ep 156 with Dr. Justin English
technologies to solve broad questions in pharmacology, with a specific focus on G-protein coupled receptor signaling
- Ep 23 with Dr. Qing Fan
structural biologist interested in the molecular mechanisms controlling how class C GPCRs transmit signals
- Ep 05 with Dr. Terry Hébert
Much of his work is based on GPCR signaling in the context to cardiovascular diseases.
- Neutrophils are itching to specialize
in Oncology and Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling
- Ep 06 with Dr. J. Silvio Gutkind
A large component of his work is centered around dysregulated signaling in cancer and the development
- Ep 03 with Dr. J. Silvio Gutkind
In this episode, Silvio discusses G protein signaling in the context of cancer, immunotherapies, and
- GPCR Retreat 2023 - Part I
These ligands stimulate receptor β-arrestin recruitment without activating canonical G protein signaling Because BAMs engage less well-conserved allosteric sites and exert pathway-specific effects on receptor signaling , they are exciting tools for linking distinct signaling pathways with their physiological effects and
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
immunofluorescence staining were used to further investigate the activation of nuclear factor-kappa B (NF-κB) signaling Moreover, GPRC5A played a role in inflammation regulation by interacting with NF-κB signaling pathway in Oncology and Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling
- Dr. GPCR Summit 2021 Live Talks
., September 13, 2021 at 5:00:00 PM Learn More >> Unconventional GPCR Signaling in the Hedgehog Pathway Velazhahan September 13, 2021 at 8:00:00 PM Learn More >> Heat Shock Protein 90 is a Novel Opioid Receptor Signaling Gloriam September 15, 2021 at 6:00:00 PM Learn More >> Hydroxycarboxylic acid receptor 3 and GPR84 signaling
- Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
G-protein coupled receptors (GPCRs) and phosphorylate their intracellular parts, which eventually blocks signal in Oncology and Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling
- Ep 134 with Dr. Neil Grimsey
To further define the role of atypical p38 signaling responses we are studying how atypical p38 controls
- Ep 01 with Dr. Paul Insel
the 1994 Nobel Prize in Physiology or Medicine for their discovery of G-proteins and their role in signal
- Ep 116 with Dr. Shivani Sachdev
communication, she is poised to make valuable contributions to the field and expand our understanding of GPCR signaling
- Ep 28 with Dr. Ross Cheloha
focused on developing new pharmacological tools via chemistry and protein engineering to interrogate GPCR signaling
- Exploration of prognostic and treatment markers in hepatocellular carcinoma via GPCR-related genes analysis
date May 15, 2024 Abstract " Background: G protein-coupled receptors (GPCRs), the biggest family of signaling in Oncology and Immunology Structural and molecular insights into GPCR function GPCR Activation and Signaling
- Trainee Symposium II
Mikel Garcia-Marcos which investigates GPCR and G protein signaling" Remi Janicot on the web Boston University pharmacology, and structural biology to study how different types of ligands modulate angiotensin receptor signaling
- Ep 108 with Dr. Kenneth A. Jacobson
approaches (synthesis, modeling, pharmacology) to study G protein-coupled receptors (GPCRs) and purinergic signaling
- Ep 139 with Dr Silvia Sposini
Hanyaloglu's lab at ICL + Dr Perrais' lab at IINS) focused on understanding the interplay between GPCR signalling
- Ep 67 with Dr. Graham Ladds
Graham studied Biochemistry at the University of Birmingham before completing a Ph.D. in yeast pheromone signaling
- G Proteins and GPCRs in Cancer: Novel Precision Targeted and Immunotherapies
He is exploiting the emerging information on dysregulated signaling circuitries and individual genomic
- Ep 38 with Dr. Alexander S. Hauser
Drug Design and Pharmacology in Copenhagen, he worked on novel analytical methods to identify human signaling
- Student Flash Presentations | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Health and Disease, Metabolism, Nervous System, Proteomics and Transcriptomics, Receptor Structure, Signaling of thermogenic fat Vasiliki Karagiannakou GAIN Domain Dynamics And Its Relevance For Adhesion GPCR Signaling However, the physiological relevance of flap flexibility on receptor activation and signaling remains We are investigating the relevance of GAIN domain dynamics for aGPCR signaling in Drosophila melanogaster Lphn3/Adgrl3) undergo physiologically relevant alternative splicing, which determined heterotrimeric signaling
- Abstract Submission Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
underlined Indicate abstract category on top left corner (up to 2 categories max) Abstract categories Signaling
- Ep 63 with Dr. Khaled Abdelrahman
He has been also studying what aspects of GPCR signaling are regulated in a sex-selective manner and