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250 items found for "cell death"
- DANGER Signals Activate G-Protein Receptor Kinases Suppressing Neutrophil Function and Predisposing to Infection After Tissue Trauma
Predicted rescue therapies were assessed in cell systems and mouse injury-dependent pneumonia models. Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR
- Ep 84 with Rosie Dawaliby
management of R&D projects and teams in the field of pharmacology, in prestigious academic laboratories as well and membrane protein biochemistry by studying membrane fusion and autophagy in yeast and mammalian cells
- Ep 109 with Dr. Katarina Nemec
Delbrueck Center in Berlin, I consolidated my knowledge of GPCRs pharmacology while performing various cell-based
- Elucidation of active components and target mechanism in Jinqiancao granules for the treatment of prostatitis and benign prostatic hyperplasia
Nitric acid (NO) inhibition was tested on the macrophage cell line RAW264.7. Prostatitis Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call
- Ep 48 with Dr Nyla Naim Dr Michael Lemieux Dr Jason Nasse from Addgene
I completed my Ph.D. in molecular and cell biology at UConn and then joined Addgene as a Quality Control
- Ep 103 with Dr Kathleen Caron
Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University
- GPCR Retreat | Dr. GPCR Ecosystem
Sponsors GPCR Retreat The GPCR Retreat focuses on advances in our understanding of how GPCRs operate in cell
- Exacerbating effects of single-dose acute ethanol exposure on neuroinflammation and amelioration by GPR110 (ADGRF1) activation
study demonstrated that pharmacological activation of GPR110 in both central and peripheral immune cells Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call for GPCR
- GPCR Retreat 2023 - Part I
Eldridge Distinguished Professor and Chair of the Department of Cell Biology & Physiology at The University Kathleen Caron on the web UNC-Chapel Hill Department of Cell Biology and Physiology UNC Lineberger Comprehensive Because BAMs engage less well-conserved allosteric sites and exert pathway-specific effects on receptor
- Pharmacological and Genetic Preclinical Models of Ghrelin Receptor Functional Selectivity to Investigate Metabolic Disease Pathophysiology
author, presenter) Kohlenbach LM -2 Zhou Y -1 Marugan JJ -3 Barak LS -1 (senior author) 1-Department of Cell
- Distinct sub-cellular signal propagation as a component of functional selectivity
He is a world-renowned expert in the field of cell signaling and GPCRs and made seminal contributions
- Ep 131 with Dr. Richard Premont
structural biology and proteomics, molecular biology and biochemical enzymology, primary and model cell
- Ep 71 with Dr. Jean Martin Beaulieu
The Beaulieu group is presently investigating how cell surface express proteins can act as allosteric
- Ep 132 with Dr. Richard Premont
structural biology and proteomics, molecular biology and biochemical enzymology, primary and model cell
- Ep 130 with Dr. Richard Premont
structural biology and proteomics, molecular biology and biochemical enzymology, primary and model cell
- Ep 133 with Dr. Richard Premont
structural biology and proteomics, molecular biology and biochemical enzymology, primary and model cell
- Plenary Lecture | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Advance 2021, PNAS 2023, Nature Metabolism 2023), recognition of amine containing hormones by GPCRs (Cell
- Ep 153 with Dr Jacek Mokrosiński
Mokrosiński "Jacek is a Senior Scientist at Novo Nordisk specializing in molecular pharmacology and cell-based He is passionate about cell-based in vitro technologies to study mechanistic properties of GPCRs and They also highlighted the need for a work-life balance and the joy of a well-done job.
- Ep 125 with Dr. Gregory Tall
Mechanical dissociation of the two fragments aided by protein binding ligands and cell movement serves
- Ep 36 with Dr. Michel Bouvier
He is a world-renowned expert in the field of cell signaling and GPCRs and made seminal contributions
- Interrogating Multiscale Receptors Functions in Space
The Beaulieu group is presently investigating how cell surface express proteins can act as allosteric
- Pancreatic ductal adenocarcinoma, β-blockers and antihistamines: A clinical trial is needed
It is predicted to become the second highest cause of cancer deaths worldwide this decade and unlike mechanistic studies, cancer biology studies and retrospective human epidemiological studies suggest that two well-known β-blocker Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call
- Ep 152 with Dr Arthur Christopoulos
long-term support from international and national competitive, charitable and commercial sources, as well Christopoulos has over 360 publications, including in leading international journals such as Nature,Science and Cell He also discussed the evolution of the field, from biochemical radioligand binding assays to cell-based a disease-specific approach, considering the clinical context and dialing in the desired effect, as well product profile (TPP) in drug development, with Arthur explaining its application in other contexts as well
- Removing the GPCR-mediated brake on exocytosis enhances insulin action, promotes adipocyte browning, and protects against diet-induced obesity
Vanderbilt University, Nashville, TN 37232, USA 4 Peking University, China 5 Department of Anatomy and Cell She oversaw an increase of the size of the Department, as well as a quintupling of its NIH funding, in
- [Inhibitory effect of downregulating G protein-coupled receptor class C group 5 member A expression on lipopolysaccharide-induced inflammatory response in human gingival fibroblasts]
Experiments were then conducted using these cells which were divided into four groups of negative control Shang , S H Ge Source Contribute to the GPCR News Coming soon Become a Contributor Classified GPCR News Call
- Ep 101 with Dr Caron Tribute Part 2
Duke Professor until his death.
- Session I | Adhesion GPCR Workshop 2024 | Dr. GPCR Ecosystem
Axel Brunger’s lab at Stanford University to study the structure and function of cell-adhesion proteins which, four papers were published in Nature (2022a, 2022b, 2021, 2020); one paper was published in Cell
- Ep 100 with Dr Caron Tribute Part 1
Duke Professor until his death.